Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Cathepsin K --- MEP | (S)-N-(cyanomethyl)-4-methyl-2-((S)-2,2,2-trifluoro-1-(4-phenoxyphenyl)ethylamino)pentanamide | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-3-methoxy-benzamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-((R)-2-(benzyloxy)-1-cyanoethyl)-2-(2-(4-chlorophenoxy)-2-methylpropanamido)-4-methylpentanamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl ester | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((S)-1-Benzyl-2-phenylamino-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 9-Cyclopentyl-6-[2-(3-imidazol-1-yl-propoxy)-phenylamino]-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((R)-2-(benzyloxy)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-yl)-1-methyl-1H-indole-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-indan-1-yl ester | Drug Info |
| Cathepsin K --- MEP | N-{(S)-1-[2-(4-Isobutoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-methoxy-benzamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((R)-2-tert-butoxy-1-cyanoethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | {1-[3-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-4-oxo-pyrrolidine-1-carbonyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 9-Cyclopentyl-6-(2-{4-[2-(4-methyl-piperazin-1-yl)-ethoxy]-benzyloxy}-phenylamino)-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | N-(benzyloxycarbonyl)-phenylalanyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((2S,3R)-2-Benzenesulfonyl-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | N-[(3R)-1-cyano-3-pyrrolidinyl]-2,5-bis(methyloxy)benzenesulfonamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-((S)-3-cyclohexyl-1-oxo-1-((S)-1-(4-(trifluoromethoxy)phenylamino)propan-2-ylamino)propan-2-yl)-tetrahydrofuran-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | {(S)-3-Methyl-1-[4-oxo-1-(4-phenoxy-benzoyl)-pyrrolidin-3-ylcarbamoyl]-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((3R,4S)-2-Oxo-4-phenylsulfanyl-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((4S,7R)-7-methyl-3-oxo-1-picolinoylazepan-4-ylamino)-3-(1-methylcyclohexyl)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-oxo-1-(2-(4-(trifluoromethoxy)phenylamino)ethylamino)propan-2-yl)-5-(3-(trifluoromethyl)phenyl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(5-chloroindolin-1-yl)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | N-{(S)-1-[2-(4-Cyclopentylmethoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-methoxy-benzamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(4-methyl-piperazin-1-yl)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-1,3-dimethyl-1H-pyrazole-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | CHEMBL450061 | Drug Info |
| Cathepsin K --- MEP | N-{(S)-3-Cyclohexyl-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-propyl}-3-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | 6-(cyclohexylamino)-9-(2-(4-methylpiperazin-1-yl)ethyl)-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid {2-[4-(4-methylpiperazin-1-yl)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((2S,3S)-2-Benzyloxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 5-Bromo-4-[2-(1-methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((S)-1-cyano-2-(4-methoxyphenyl)ethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-(1,3,4-thiadiazol-2-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)-3-tert-butyl-1-methyl-1H-pyrazole-5-carboxamide | Drug Info |
| Cathepsin K --- MEP | (S)-3-tert-butyl-N-(1-(cyanomethylamino)-3-(3-(5-(methoxymethyl)-1,3,4-oxadiazol-2-yl)phenyl)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-(toluene-2-sulfonylamino)-benzamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[3-(2-imidazol-1-yl-ethoxy)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | SID85147302 | Drug Info |
| Cathepsin K --- MEP | (S)-N-((R)-2-(benzyloxy)-1-cyanoethyl)-4-methyl-2-(2-(4-phenylpiperidin-1-yl)acetamido)pentanamide | Drug Info |
| Cathepsin K --- MEP | (S)-2-((S)-1-(4-benzoylphenyl)-2,2,2-trifluoroethylamino)-N-(cyanomethyl)-4-methylpentanamide | Drug Info |
| Cathepsin K --- MEP | (S)-4,4-dimethyl-2-oxo-tetrahydrofuran-3-yl (S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(4-chlorophenylamino)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-3-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | {(S)-1-[(S)-1-Benzyl-2-(4-morpholin-4-yl-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | 4-Isopropyl-N-{1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-benzamide | Drug Info |
| Cathepsin K --- MEP | 6-[4-(4-Acetyl-piperazin-1-yl)-phenoxymethyl]-7-(2-cyclohexyl-ethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | 6-(4-chlorobenzyl)-7-(2-cyclopentylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | N-{1-[2-(4-Methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-propyl-benzamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cyclohexyl-1-((S)-4-(methylsulfonyl)-1-(4-(trifluoromethoxy)phenylamino)butan-2-ylamino)-1-oxopropan-2-yl)morpholine-4-carboxamide | Drug Info |
| Cathepsin K --- MEP | 4-[2-(1-Methyl-piperidin-4-yl)-ethoxy]-6-[(spiro[2.5]oct-6-ylmethyl)-amino]-pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | (S)-ethyl 3-(4-cyclohexyl-2-(3-methoxybenzamido)butanamido)-4-(5-fluoroindolin-1-yl)butanoate | Drug Info |
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