Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(2-(2,3-dihydrobenzo[b]-[1,4]dioxine-6-sulfonamido)3-methylbutyryl)-1,4-diazepan-1-yl)-pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | (R)-3-Phenyl-2-[4-(2-p-tolyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-propionic acid | Drug Info |
| MMP2 --- MMP9 | 2-(7-Benzyloxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide | Drug Info |
| MMP2 --- MMP9 | (R)-4-Amino-2-[(biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-butyramide | Drug Info |
| MMP2 --- MMP9 | 5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(4-fluoro-phenyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione | Drug Info |
| MMP2 --- MMP9 | 2-amino-N-(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl)acetamide | Drug Info |
| MMP2 --- MMP9 | (R)-N-hydroxy-3-(4-(4-methoxyphenoxy)phenylsulfonyl)thiazolidine-4-carboxamide | Drug Info |
| MMP2 --- MMP9 | (3R,4S)-3-Hydroxycarbamoyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-phenylcarbamoyl]-piperidine-1-carboxylic acid cyclopropyl ester | Drug Info |
| MMP2 --- MMP9 | N-(1-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-N-isopropyl-4-phenoxybenzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-(4-Cyanobenzoyl))piperazin-1-yl)-5-(4-phenoxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | 5-(4-Hydroxy-phenyl)-5-methyl-pyrimidine-2,4,6-trione | Drug Info |
| MMP2 --- MMP9 | (R)-3-Methyl-2-[4-(4-nitro-benzoylamino)-benzenesulfonylamino]-butyric acid | Drug Info |
| MMP2 --- MMP9 | (6S,7S)-5-acetyl-6-(4-phenyl-3,4-dihydro-2H-pyridine-1-carbonyl)-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(4-bromobenzoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(cyclobutanecarbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | methyl 4-(3-(N-hydroxyformamido)-4-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)butyl)benzoate | Drug Info |
| MMP2 --- MMP9 | (S)-N-hydroxy-2-(isopropylamino)-3-(N-(4-(4-(trifluoromethyl)phenoxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | 6-Benzyloxy-2-(2,5-dichloro-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide | Drug Info |
| MMP2 --- MMP9 | 5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione | Drug Info |
| MMP2 --- MMP9 | 5-[4-(2-Bromo-ethyl)-piperazin-1-yl]-5-[4-(4-bromo-phenoxy)-phenyl]-pyrimidine-2,4,6-trione | Drug Info |
| MMP2 --- MMP9 | 5-[4-(2-Hydroxy-ethyl)-piperazin-1-yl]-5-[4-(4-iodo-phenoxy)-phenyl]-pyrimidine-2,4,6-trione | Drug Info |
| MMP2 --- MMP9 | (6S,7S)-7-hydroxycarbamoyl-6-(3-phenyl-2,5-dihydro-pyrrole-1-carbonyl)-5-aza-spiro[2.5]octane-5-carboxylic acid methyl ester | Drug Info |
| MMP2 --- MMP9 | (3R,4S)-1-(1-Methyl-1H-imidazole-4-sulfonyl)-piperidine-3,4-dicarboxylic acid 3-hydroxyamide 4-{[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-amide} | Drug Info |
| MMP2 --- MMP9 | 5-[4-(4-Bromo-phenoxy)-phenyl]-5-[4-(4-nitro-phenyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione | Drug Info |
| MMP2 --- MMP9 | (-)-(R)-4-(4-chlorophenoxy)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)benzamide | Drug Info |
| MMP2 --- MMP9 | 4-(4-chlorophenoxy)-N-(1-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-N-(2-(4-methylpiperazin-1-yl)ethyl)benzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(morpholine-4-carbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | (6S,7S)-6-(4-m-tolyl-piperazine-1-carbonyl)-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide | Drug Info |
| MMP2 --- MMP9 | (6S,7S)-6-[4-(3,5-difluoro-phenyl)-3,6-dihydro-2H-pyridine-1-carbonyl]-5-aza-spiro[2.5]octane-7-carboxylic acid hydroxyamide | Drug Info |
| MMP2 --- MMP9 | (R)-3-Phenyl-2-[4-(2-phenyl-2H-tetrazol-5-yl)-benzenesulfonylamino]-propionic acid | Drug Info |
| MMP2 --- MMP9 | (S)-N,2-dihydroxy-3-(15-phenyl-N-(4-(p-tolyloxy)phenyl)methan-15-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | (S)-2-amino-N-hydroxy-3-(N-(4-(p-tolyloxy)phenyl)methan-2-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | N-(1-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)-N-methyl-4-(p-tolyloxy)benzenesulfonamide | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(6-(trifluoromethyl)nicotinoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | N-hydroxy-3-(2-oxo-2H-chromen-3-yl)propanamide | Drug Info |
| MMP2 --- MMP9 | (S)-3-(N-(4-(4-fluorophenylthio)phenyl)methan-15-ylsulfonamido)-N,2-dihydroxypropanamide | Drug Info |
| MMP2 --- MMP9 | N-Hydroxy-2-{3-methyl-3-[4-(2-nitro-benzyloxy)-phenyl]-2-oxo-pyrrolidin-1-yl}-propionamide | Drug Info |
| MMP2 --- MMP9 | (R)-2-[4-(4-Methoxy-benzoylamino)-benzenesulfonylamino]-3-methyl-butyric acid | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(cyclopropylcarbonyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | 5-(4-Phenoxyphenyl)-5-(4-(3-phenylpropanoyl)-1,4-diazepan-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione | Drug Info |
| MMP2 --- MMP9 | N-Hydroxy-2-{4-[5-(4-methoxy-phenyl)-thiazol-2-yl]-benzenesulfonylamino}-3-methyl-butyramide | Drug Info |
| MMP2 --- MMP9 | (R)-2-(Biphenyl-4-sulfonylamino)-N-hydroxy-3-(1H-indol-3-yl)-propionamide | Drug Info |
| MMP2 --- MMP9 | 2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide | Drug Info |
| MMP2 --- MMP9 | 3-Cyclopentylmethyl-4-oxo-4-((4-phenylethynyl)phenyl)butyric acid | Drug Info |
| MMP2 --- MMP9 | 4-Benzylsulfanyl-2-[[(dicyclohexylmethyl-carbamoyl)-methyl]-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-butyramide | Drug Info |
| MMP2 --- MMP9 | (S)-N,2-dihydroxy-3-(N-(4-(5-(trifluoromethyl)pyridin-2-yloxy)phenyl)methan-15-ylsulfonamido)propanamide | Drug Info |
| MMP2 --- MMP9 | N-hydroxy-N-(4-morpholino-1-(4-(4-(trifluoromethoxy)phenoxy)phenylsulfonyl)butan-2-yl)formamide | Drug Info |
| MMP2 --- MMP9 | 2-{4-[4-(4-cyano-phenyl)-piperazin-1-yl]-benzenesulfonyl}-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyric acid | Drug Info |
| MMP2 --- MMP9 | (R)-3-(1H-Indol-3-yl)-2-(4-p-tolylethynyl-benzenesulfonylamino)-propionic acid | Drug Info |
| MMP2 --- MMP9 | (R)-N-(1-hydroxy-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl)-N-(2-morpholinoethyl)-5-(p-tolylethynyl)thiophene-2-sulfonamide | Drug Info |
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