Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| PKCA --- NPKC delta | (R)-2-{2,6-Dihydroxy-4-[3-(4-hydroxy-benzoylamino)-azepan-4-ylcarbamoyl]-benzoyl}-3-hydroxy-benzoic acid | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid 4-(4-hydroxy-benzyl)-pyrrolidin-3-yl ester | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (R)-2-(4-hydroxy-benzoylamino)-indan-1-yl ester | Drug Info |
| PKCA --- NPKC delta | ENZASTAURIN | Drug Info |
| PKCA --- NPKC delta | 4-[2-(2,2-Dimethyl-propionyloxymethoxycarbonyl)-6-hydroxy-benzoyl]-3,5-dihydroxy-benzoic acid (3R,4R)-4-(4-hydroxy-benzoylamino)-pyrrolidin-3-yl ester | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid 3-(4-hydroxy-phenyl)-1-methyl-propyl ester | Drug Info |
| PKCA --- NPKC delta | 1-(3-Hydroxypropylamino-3-(2-methylaminopyridin-4-yl)[2,6]-naphthyridine | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid 4-(4-hydroxy-phenyl)-butyl ester | Drug Info |
| PKCA --- NPKC delta | 3-(1-Benzo[b]thiophen-2-yl-1H-indol-3-yl)-4-[1-(3-dimethylamino-propyl)-1H-indazol-3-yl]-pyrrole-2,5-dione | Drug Info |
| PKCA --- NPKC delta | 18-dimethylaminomethyl-(18S)-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione; methane sulphonic acid salt | Drug Info |
| PKCA --- NPKC delta | bis(3-(trifluoromethyl)benzyl)5-(hydroxymethyl)isophthalate | Drug Info |
| PKCA --- NPKC delta | [2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,3-dihydrofuryl]methyl 3-(4-[2-(4-Methylphenyl)ethynyl]phenoxy)propanoate | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (S)-2-benzenesulfonylamino-3-(4-hydroxy-phenyl)-propyl ester | Drug Info |
| PKCA --- NPKC delta | Dodecanoic acid (3S,3aR,8R,8aS)-3-hydroxymethyl-8-isopropyl-8-methyl-1-oxo-1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrrol-6-yl ester | Drug Info |
| PKCA --- NPKC delta | 3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione | Drug Info |
| PKCA --- NPKC delta | 3-[1-(1-Benzyl-pyrrolidin-3-yl)-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-isopropyl-cyclopentyl ester | Drug Info |
| PKCA --- NPKC delta | 23-ethyl-17,20-dioxa-4,14,23,26-tetraazahexacyclo[24.6.1.17,14.02,6.08,13.027,32]tetratriaconta-1(33),2(6),7(34),8(13),9,11,27(32),28,30-nonaene-3,5-dione | Drug Info |
| PKCA --- NPKC delta | 18-aminomethyl-(18S)-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione | Drug Info |
| PKCA --- NPKC delta | 18-(1,4-oxazinan-4-ylmethyl)-(18S)-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (3R,5R)-2-((S)-4-hydroxy-benzoylamino)-4-hydroxymethyl-cyclopentyl ester | Drug Info |
| PKCA --- NPKC delta | Benzolactam-V8 | Drug Info |
| PKCA --- NPKC delta | 2-{2,6-Dihydroxy-4-[(3R,4R)-2-(4-hydroxy-benzoylamino)-cyclopentyloxymethyl]-benzoyl}-3-hydroxy-benzoic acid | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (3R,4R)-3-(4-hydroxy-benzoylamino)-1-(toluene-4-sulfonyl)-azepan-4-yl ester | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-methanesulfonyl-cyclopentyl ester | Drug Info |
| PKCA --- NPKC delta | 18-hydroxymethyl-(18S)-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione | Drug Info |
| PKCA --- NPKC delta | N-cyclohexyl-4-(1-(piperazin-1-yl)-2,6-naphthyridin-3-yl)pyridin-2-amine | Drug Info |
| PKCA --- NPKC delta | 3-(2-Chloropyridin-4-yl)-1-piperazin-1-yl[2,6]naphthyridine | Drug Info |
| PKCA --- NPKC delta | Tetradecanedioic acid ((S)-5-hydroxymethyl-2-isopropyl-1-methyl-3-(S)-oxo-1,2,3,4,5,6-hexahydro-benzo[e][1,4]diazocin-8-yl)-amide ((S)-5-hydroxymethyl-2-isopropyl-1-(S)-methyl-3-oxo-1,2,3,4,5,6-hexahydro-benzo[e][1,4]diazocin-9-yl)-amide | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (3S,4R)-3-(4-hydroxy-benzoylamino)-thiepan-4-yl ester | Drug Info |
| PKCA --- NPKC delta | 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-[3-isobutyl-5-methyl-hex-(E)-ylidene]-tetrahydro-furan-2-ylmethyl ester | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (3S,5R)-4-aminomethyl-2-((S)-4-hydroxy-benzoylamino)-cyclopentyl ester | Drug Info |
| PKCA --- NPKC delta | 2,2-Dimethyl-thiopropionic acid O-{2-hydroxymethyl-4-[3-isobutyl-5-methyl-hex-(E)-ylidene]-5-oxo-tetrahydro-furan-2-ylmethyl} ester | Drug Info |
| PKCA --- NPKC delta | 18-tetrahydro-1H-1-pyrrolylmethyl-(18S)-17-oxa-4,14,21-triazahexacyclo[19.6.1.17,14.02,6.08,13.022,27]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R,4R)-4-hydroxy-2-(4-hydroxy-benzoylamino)-cyclopentyl ester | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid 3-(4-hydroxy-phenyl)-2-(naphthalene-2-sulfonylamino)-propyl ester | Drug Info |
| PKCA --- NPKC delta | [2-(Hydroxymethyl)-4-(methylethylidene)-5-oxo-2-2,3-dihydrofuryl]methyl 4-[2-(4-Methylphenyl)ethynyl]benzoate | Drug Info |
| PKCA --- NPKC delta | 1-(piperazin-1-yl)-3-(pyridin-4-yl)-2,6-naphthyridine | Drug Info |
| PKCA --- NPKC delta | 3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione | Drug Info |
| PKCA --- NPKC delta | (3S,3aR,8R,8aS)-6-Dec-1-ynyl-3-hydroxymethyl-8-isopropyl-8-methyl-3,3a,8,8a-tetrahydro-2H-indeno[1,2-c]pyrrol-1-one | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (3S,4R)-3-(4-hydroxy-benzoylamino)-oxepan-4-yl ester | Drug Info |
| PKCA --- NPKC delta | (R)-2-{2,6-Dihydroxy-4-[(3R,4R)-4-(4-hydroxy-benzoylamino)-pyrrolidin-3-ylcarbamoyl]-benzoyl}-3-hydroxy-benzoic acid | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (S)-4-(4-hydroxy-benzoylamino)-pyrrolidin-3-yl ester | Drug Info |
| PKCA --- NPKC delta | 5-(2,2-Dimethyl-propoxymethyl)-5-hydroxymethyl-3-[3-isobutyl-5-methyl-hex-(E)-ylidene]-dihydro-furan-2-one | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-cycloheptyl ester | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-2-(4-hydroxy-benzoylamino)-4-methylcarbamoyl-cyclopentyl ester | Drug Info |
| PKCA --- NPKC delta | 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid 2-(4-hydroxy-benzyl)-cyclopentyl ester | Drug Info |
| PKCA --- NPKC delta | 3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1H-indol-3-yl]-pyrrole-2,5-dione | Drug Info |
| PKCA --- NPKC delta | 2,2-Dimethyl-propionic acid 2-hydroxymethyl-4-[3-isobutyl-5-methyl-hex-(E)-ylidene]-5-thioxo-tetrahydro-furan-2-ylmethyl ester | Drug Info |
| PKCA --- NPKC delta | 3-(8-Amino-6,7,8,9-tetrahydro-pyrido[1,2-a]indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione | Drug Info |
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