Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| VEGFR2 --- CSrc | N-(4-methyl-3-(1-(6-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxyphenyl)-5-(cyclohexyloxy)-7-(3-morpholinopropoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 2-(4-(6-(6-(2-(2-chloro-6-methylphenylamino)-1H-benzo[d]imidazol-1-yl)pyrimidin-4-ylamino)-2-methylpyrimidin-4-yl)piperazin-1-yl)ethanol | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-cyclopropyl-1H-pyrazole-5-carboxamide | Drug Info |
| VEGFR2 --- CSrc | 2-((3,5-dimethoxy)-4-((2-(4-morpholinyl)ethyl)oxy)phenyl)amino)-6-(2,6-dimethylphenyl)-pyrimido-[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxyphenyl)-5-isopropoxy-7-(3-morpholinopropoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 4-methyl-3-(1-(6-(2-(4-methylpiperazin-1-yl)ethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 4-methyl-3-(1-(4-(3-(4-methylpiperazin-1-yl)propylamino)-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 2,6-dimethylphenyl-2,4-bis(methyloxy)phenyl(2-((3-fluoro-4-((2-(4-methyl-1-piperazinyl)ethyl)oxy)phenyl)amino)-4-pyrimidinyl)carbamate | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxypyridin-3-yl)-7-(3-morpholinopropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | N-(2-chloro-5-methoxypyridin-3-yl)-5-isopropoxy-7-(3-morpholinopropoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-bromophenyl)-4-methylbenzamide | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-(2-cyanoethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | CHEMBL426161 | Drug Info |
| VEGFR2 --- CSrc | (R,S)-N-(2-chloro-5-methoxyphenyl)-7-(3-morpholinopropoxy)-5-(tetrahydrofuran-3-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-methylbenzamide | Drug Info |
| VEGFR2 --- CSrc | N-(4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenyl)-3-cyclopentylpropanamide | Drug Info |
| VEGFR2 --- CSrc | Benzofuran-4-yl-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine | Drug Info |
| VEGFR2 --- CSrc | CHEMBL384260 | Drug Info |
| VEGFR2 --- CSrc | 7-phenyl-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin- | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-(2-hydroxyethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-N-(3-isopropylphenyl)-4-methylbenzamide | Drug Info |
| VEGFR2 --- CSrc | CHEMBL169186 | Drug Info |
| VEGFR2 --- CSrc | (5-Fluoro-benzo[1,3]dioxol-4-yl)-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine | Drug Info |
| VEGFR2 --- CSrc | (3-Chloro-1H-indol-7-yl)-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine | Drug Info |
| VEGFR2 --- CSrc | CHEMBL216105 | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-(2-methoxyethylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | N-(2,3-dihydro-1,4-benzodioxin-5-yl)-7-(2-pyrrolidin-1-ylethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 2-((4-((3-(dimethylamino)propyl)oxy)-phenyl)amino)-6-(2,6-dimethylphenyl)-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-1-tert-butyl-5-((4-methylpiperazin-1-yl)methyl)-1H-pyrazole-3-carboxamide | Drug Info |
| VEGFR2 --- CSrc | 2,6-dimethylphenyl-2,4-bis(methyloxy)phenyl(2-((4-((3-(1-piperidinyl)propyl)oxy)phenyl)amino)-4-pyrimidinyl)carbamate | Drug Info |
| VEGFR2 --- CSrc | 6-(2,6-dimethylphenyl)-2-((3-(methoxy)-4-((3-(4-methyl-1-piperazinyl)propyl)-oxy)phenyl)amino)pyrimido[5',4':5,6]-pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
| VEGFR2 --- CSrc | N-(benzo[d][1,3]dioxol-4-yl)-7-(2-(pyrrolidin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | 3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | phenyl4-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenylcarbamate | Drug Info |
| VEGFR2 --- CSrc | N-(4-methyl-3-(1-(6-(1-methylpiperidin-4-ylamino)pyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)phenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | CHEMBL199110 | Drug Info |
| VEGFR2 --- CSrc | (2-Chloro-5-ethoxy-phenyl)-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine | Drug Info |
| VEGFR2 --- CSrc | CHEMBL198752 | Drug Info |
| VEGFR2 --- CSrc | N-(3-chloro-6-methoxypyridin-2-yl)-5-isopropoxy-7-(2-(pyrrolidin-1-yl)ethoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | CHEMBL198701 | Drug Info |
| VEGFR2 --- CSrc | N-(3-(1-(6-aminopyrimidin-4-yl)-1H-benzo[d]imidazol-2-ylamino)-4-methylphenyl)-3-(trifluoromethyl)benzamide | Drug Info |
| VEGFR2 --- CSrc | CHEMBL383593 | Drug Info |
| VEGFR2 --- CSrc | isobutyl4-(7-amino-3-(3-(4-(2-aminoacetyl)piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenylcarbamate | Drug Info |
| VEGFR2 --- CSrc | 4-(7-amino-3-(3-(4-methylpiperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol | Drug Info |
| VEGFR2 --- CSrc | N-1,3-benzodioxol-4-yl-7-(3-pyrrolidin-1-ylpropoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | (3-Chloro-benzofuran-7-yl)-[6-methoxy-7-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine | Drug Info |
| VEGFR2 --- CSrc | N-(5-chloro-1,3-benzodioxol-4-yl)-5-morpholin-4-yl-7-(2-pyrrolidin-1-ylethoxy)quinazolin-4-amine | Drug Info |
| VEGFR2 --- CSrc | (2-Chloro-5-methoxy-phenyl)-[6-methoxy-7-(4-methyl-piperazin-1-ylmethoxy)-quinazolin-4-yl]-amine | Drug Info |
| VEGFR2 --- CSrc | 6-(2,6-dimethylphenyl)-2-((3-fluoro-4-((2-(4-methyl-1-piperazinyl)ethyl)oxy)-phenyl)amino)pyrimido[5',4':5,6]-pyrimido[1,2-a]benzimidazol-5(6H)-one | Drug Info |
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