Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| VEGFR2 --- FGFR1 | CHEMBL1762531 | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762527 | Drug Info |
| VEGFR2 --- FGFR1 | 1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[4-(morpholin-4-ylmethyl)-3-(trifluoromethyl)phenyl]urea | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762526 | Drug Info |
| VEGFR2 --- FGFR1 | 1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}urea | Drug Info |
| VEGFR2 --- FGFR1 | N-(4-Benzyloxy-butyl)-N-[2-(3-tert-butyl-ureido)-3-(3,5-dimethoxy-phenyl)-3,4-dihydro-[1,6]naphthyridin-7-yl]-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | N-(3-Benzyloxy-propyl)-N-[2-(3-tert-butyl-ureido)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridin-7-yl]-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | N-[2-(3-tert-Butyl-ureido)-3-(3,5-dimethoxy-phenyl)-3,4-dihydro-[1,6]naphthyridin-7-yl]-N-(3-hydroxy-propyl)-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | 1-tert-Butyl-3-[3-(3,5-dimethoxy-phenyl)-7-(3-phenoxy-propylamino)-[1,6]naphthyridin-2-yl]-urea | Drug Info |
| VEGFR2 --- FGFR1 | N-(4-Benzyloxy-butyl)-N-[2-(3-tert-butyl-ureido)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridin-7-yl]-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | 1-tert-Butyl-3-[3-(3,5-dimethoxy-phenyl)-7-(5-phenoxy-pentylamino)-[1,6]naphthyridin-2-yl]-urea | Drug Info |
| VEGFR2 --- FGFR1 | 1-(5-tert-butylisoxazol-3-yl)-3-(2-chloro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl)urea | Drug Info |
| VEGFR2 --- FGFR1 | 1-(3-tert-Butyl-1-methyl-1H-pyrazol-5-yl)-3-{2-chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea | Drug Info |
| VEGFR2 --- FGFR1 | 1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{4-[(1-methylpiperidin-4-yl)oxy]-3-(trifluoromethyl)phenyl}urea | Drug Info |
| VEGFR2 --- FGFR1 | 3-(3,5-Dimethoxy-phenyl)-N*7*-[3-(4-methyl-piperazin-1-yl)-propyl]-[1,6]naphthyridine-2,7-diamine | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762529 | Drug Info |
| VEGFR2 --- FGFR1 | 1-[2-Chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5H-pyrrolo [3,2-d]pyrimidin-4-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762534 | Drug Info |
| VEGFR2 --- FGFR1 | 1-tert-Butyl-3-[3-(3,5-dimethoxy-phenyl)-7-(4-phenoxy-butylamino)-[1,6]naphthyridin-2-yl]-urea | Drug Info |
| VEGFR2 --- FGFR1 | 2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-[1,2,4]oxadiazol-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino]-N-methoxy-benzamide | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762549 | Drug Info |
| VEGFR2 --- FGFR1 | N-(5-Benzyloxy-pentyl)-N-[2-(3-tert-butyl-ureido)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridin-7-yl]-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | N2-(3,5-dimorpholinophenyl)-N4-(3-methoxyphenyl)-N4-methylpyrimidine-2,4-diamine | Drug Info |
| VEGFR2 --- FGFR1 | 1-(1-tert-Butyl-1H-pyrazol-4-yl)-3-{2-chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}urea | Drug Info |
| VEGFR2 --- FGFR1 | N-[2-(3-tert-Butyl-ureido)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridin-7-yl]-N-(3-hydroxy-propyl)-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | N2-(3,5-dimorpholinophenyl)-N4-methyl-N4-m-tolylpyrimidine-2,4-diamine | Drug Info |
| VEGFR2 --- FGFR1 | N4-(3-chlorophenyl)-N2-(3,5-dimorpholinophenyl)-N4-methylpyrimidine-2,4-diamine | Drug Info |
| VEGFR2 --- FGFR1 | 5-[6-(5-Dimethylaminomethyl-[1,3,4]oxadiazol-2-yl)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino]-2,4-difluoro-N-methoxy-benzamide | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762528 | Drug Info |
| VEGFR2 --- FGFR1 | N*7*-(4-Diethylamino-butyl)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridine-2,7-diamine | Drug Info |
| VEGFR2 --- FGFR1 | 1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}urea | Drug Info |
| VEGFR2 --- FGFR1 | N-[2-(3-tert-Butyl-ureido)-3-(3,5-dimethoxy-phenyl)-[1,6]naphthyridin-7-yl]-N-(5-hydroxy-pentyl)-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | N2-(3,5-dimorpholinophenyl)-N4-(5-methoxypyridin-3-yl)-N4-methylpyrimidine-2,4-diamine | Drug Info |
| VEGFR2 --- FGFR1 | 1-(3-((2-(3,5-dimorpholinophenylamino)pyrimidin-4-yl)(methyl)amino)-4-methylphenyl)ethanol | Drug Info |
| VEGFR2 --- FGFR1 | 1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[4-morpholin-4-yl-3-(trifluoromethyl)phenyl]urea | Drug Info |
| VEGFR2 --- FGFR1 | N-[2-(3-tert-Butyl-ureido)-3-(3,5-dimethoxy-phenyl)-3,4-dihydro-[1,6]naphthyridin-7-yl]-N-(4-hydroxy-butyl)-acetamide | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762521 | Drug Info |
| VEGFR2 --- FGFR1 | CHEMBL1762522 | Drug Info |
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