Target Pair Drug Name
Ftase --- FPTase 2-[11-[2-(2-methoxyphenyl)acetyl]-1-phenyl-(1R,8R,9S,13S)-11-azatetracyclo[6.5.2.02,7.09,13]pentadeca-2,4,6-trien-9-ylcarboxamido]acetic acid (RPR113258) Drug Info
MMP13 --- MMP1 4-benzylbenzyl(2-(cyclobutylmethyl)-3-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-ylamino)-3-oxopropyl)phosphinic acid Drug Info
EGFR3 --- HER2 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)propiolaldehyde O-2-morpholinoethyl oxime Drug Info
Renin --- Cathepsin D N-[2-(5-Amino-thiophen-3-yl)-1-(1-cyclohexylmethyl-2,4-dihydroxy-hexylcarbamoyl)-ethyl]-2-(morpholine-4-sulfonylamino)-3-phenyl-propionamide Drug Info
Ftase --- FPTase 2-{2-[4-(2-Amino-3-methylsulfanyl-propylamino)-3-methyl-butylamino]-3-phenyl-propionylamino}-4-methylsulfanyl-butyric acid (FTI1) Drug Info
MMP13 --- MMP1 4-(4-Phenoxy-benzenesulfonylamino)-tetrahydro-pyran-4-carboxylic acid hydroxyamide Drug Info
EGFR3 --- HER2 4-(4,4-Dihydroxy-piperidin-1-yl)-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide Drug Info
Renin --- Cathepsin D {1-[1-[1-Cyclohexylmethyl-2-hydroxy-2-(5-methoxymethyl-1-methyl-2-oxo-pyrrolidin-3-yl)-ethylcarbamoyl]-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester Drug Info
Ftase --- FPTase (R)-2-({(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3,3-dimethyl-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-4-methylsulfanyl-butyric acid methyl ester Drug Info
MMP13 --- MMP1 1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cyclobutanecarboxylic acid hydroxyamide Drug Info
EGFR3 --- HER2 Candesartan Drug Info
Renin --- Cathepsin D (1S,5S)-7-(4-(3-(2-chloro-3,6-difluorophenoxy)propyl)phenyl)-N-cyclopropyl-N-(2,3-dichlorobenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide Drug Info
Ftase --- FPTase 6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethyl]-3''-methoxy-biphenyl-3-carbonitrile Drug Info
MMP13 --- MMP1 1-(4-Methoxy-benzenesulfonylamino)-cyclopentanecarboxylic acid hydroxyamide Drug Info
EGFR3 --- HER2 N-[4-(3-Chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide Drug Info
Renin --- Cathepsin D (R)-2-amino-4-(4-(difluoromethoxy)phenyl)-4-(4-fluoro-3-(5-fluoropent-1-ynyl)phenyl)-1-methyl-1H-imidazol-5(4H)-one Drug Info
Ftase --- FPTase {2-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-oxo-ethyl}-carbamic acid benzyl ester Drug Info
MMP13 --- MMP1 (2R,3S)-4-Acetyl-1-[4-(5-fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-methyl-piperazine-2-carboxylic acid hydroxyamide Drug Info
EGFR3 --- HER2 2-{2-Chloro-4-[3-cyano-6-(4-dimethylamino-but-2-enoylamino)-7-methoxy-quinolin-4-ylamino]-phenylsulfanyl}-1-methyl-3H-imidazol-1-ium Drug Info
Renin --- Cathepsin D 2-[2-(Morpholine-4-sulfonylamino)-3-phenyl-propionylamino]-pent-4-enoic acid (1-cyclohexylmethyl-2,4-dihydroxy-hexyl)-amide Drug Info
Ftase --- FPTase 4-(5-{[3-(3-Chloro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile Drug Info
MMP13 --- MMP1 8-bromo-4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxyquinoline-3-carboxamide Drug Info
EGFR3 --- HER2 (3R,5S)-5-((4-(5-(pyridin-2-yloxy)naphthalen-2-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate Drug Info
Renin --- Cathepsin D (2S,4S,5S)-6-Cyclohexyl-4-hydroxy-5-{(S)-3-(1H-imidazol-4-yl)-2-[2-(naphthalen-1-yloxy)-acetylamino]-propionylamino}-2-isopropyl-hexanoic acid {(S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide Drug Info
Ftase --- FPTase N-Cyclopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylmethyl-acetamide Drug Info
MMP13 --- MMP1 4-(4'-Fluoro-biphenyl-4-sulfonylamino)-tetrahydro-pyran-4-carboxylic acid hydroxyamide Drug Info
EGFR3 --- HER2 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(4-fluoro-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide Drug Info
mTOR --- AKT N-(6-(6-Chloro-5-(4-chlorophenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide Drug Info
Ftase --- FPTase 5-{[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-biphenyl-2-carboxylic acid benzylamide Drug Info
MMP13 --- MMP1 (3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-6-(2-(diethylamino)ethyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide Drug Info
EGFR3 --- HER2 4-amino-6-(1-benzyl-1H-indazol-5-ylamino)pyrimidine-5-carbaldehyde O-methyl oxime Drug Info
mTOR --- AKT N-(6-(6-Chloro-5-(4-(trifluoromethyl)phenylsulfonamido)pyridin-3-yl)benzo[d]thiazol-2-yl)acetamide Drug Info
Ftase --- FPTase 1-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-methyl-2-(1-oxy-pyridin-4-yl)-propan-1-one Drug Info
MMP13 --- MMP1 (2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide Drug Info
EGFR3 --- MCSF Methyl-phenyl-(9H-purin-6-yl)-amine Drug Info
mTOR --- AKT N-(6-(6-(4-Methoxyphenylsulfonamido)pyrazin-2-yl)benzo-[d]thiazol-2-yl)acetamide Drug Info
Ftase --- FPTase 1-[(2R,3R)-3-(2-Chloro-thiophen-3-ylmethoxy)-2,3-dihydro-benzo[b]thiophen-2-ylmethyl]-1H-imidazole Drug Info
MMP13 --- MMP1 (3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-6-(2-hydroxyethyl)-2,2-dimethylthiomorpholine-3-carboxamide Drug Info
EGFR3 --- VEGFR1 2-({4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzyl}-methyl-amino)-ethanol Drug Info
mTOR --- AKT trans-2-amino-8-((1r,4r)-4-hydroxycyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpteridin-7(8H)-one Drug Info
Ftase --- FPTase 4-[3-(4-Chloro-phenyl)-1-hydroxy-1-(3-methyl-3H-imidazol-4-yl)-prop-2-ynyl]-2-naphthalen-1-yl-benzonitrile Drug Info
MMP13 --- MMP1 (4-Benzyl-benzyl)-[2-((S)-2,2-dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-m-tolyl-butyl]-phosphinic acid Drug Info
EGFR3 --- VEGFR1 (2-Methyl-1H-indol-5-yl)-(2-{4-[(2-pyridin-1-yl-ethylamino)-methyl]-phenyl}-thieno[3,2-b]pyridin-7-yl)-amine Drug Info
mTOR --- DNPK1 CHEMBL179242 Drug Info
Ftase --- FPTase (S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-naphthalene-1-carbonyl]-amino}-4-methylsulfanyl-butyric acid Drug Info
MMP13 --- MMP1 2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide Drug Info
mTOR --- PI3K gamma 1-[4-(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)-phenyl]-3-thiophen-2-ylurea Drug Info
Ftase --- FPTase (S)-2-(5-((R)-2-amino-3-mercaptopropylamino)biphenyl-2-ylcarboxamido)-4-(methylthio)butanoic acid Drug Info
MMP13 --- MMP1 N-Hydroxy-2-(4-methoxy-benzenesulfonylamino)-2-methyl-propionamide Drug Info
mTOR --- PI3K gamma 4-({[4-(3-Ethyl-7-morpholin-4-yl-3H-[1,2,3]-triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)-N,N-dimethylbenzamide Drug Info

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