Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| PPAR gamma --- PPAR delta | 2-(5-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propoxy)-1H-indol-1-yl)acetic acid | Drug Info |
| HDAC1 --- HDAC2 | 4-(3-(4-(4-Methylbenzyloxy)-3-methoxyphenyl)propanamido)-N-hydroxybenzamide | Drug Info |
| EGFR3 --- VEGFR1 | 6-methoxy-7-(1-methylpiperidin-4-yloxy)-4-((1R,2S)-2-phenylcyclopropylamino)quinoline-3-carbonitrile | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-((2-(4-tert-butylphenyl)-4-methylthiazole-5-carboxamido)methyl)phenoxy)-2-methylpropanoic acid | Drug Info |
| HDAC1 --- HDAC2 | methyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate | Drug Info |
| Erbeta --- ER | (2R,3S)-5-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-isopropoxy-3-(4-((5-m-tolyl-1,2,4-oxadiazol-3-yl)methoxy)phenyl)propanoic acid | Drug Info |
| HDAC1 --- HDAC2 | 4-(3-(4-(2-Methylbenzyloxy)-3-methoxyphenyl)propanamido)-N-hydroxybenzamide | Drug Info |
| Erbeta --- ER | (E)-7,8-Bis-(4-hydroxy-phenyl)-dec-7-enoic acid methyl-(3-pentylsulfanyl-propyl)-amide | Drug Info |
| PPAR gamma --- PPAR delta | rac-2-{3-[(4-adamantan-1-yl-benzoylamino)-methyl]-4-propoxy-benzyl}-butyric acid | Drug Info |
| HDAC1 --- HDAC2 | [4-(4-amino-biphenyl-3-ylcarbamoyl)-benzyl]-carbamic acid methyl ester | Drug Info |
| Erbeta --- ER | 2-Bromo-N-((S)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ylmethyl)-acetamide | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(N-butyl-N-(4'-chloro-2-methylbiphenyl-3-yl)sulfamoyl)-2-cyclohexylphenoxy)propanoic acid | Drug Info |
| HDAC1 --- HDAC4 | N-hydroxy-3-(4-(4-methylphenylsulfonamido)phenyl)acrylamide | Drug Info |
| Erbeta --- ER | 1-Chloro-6-(4-hydroxy-2-methyl-phenyl)-naphthalen-2-ol | Drug Info |
| PPAR gamma --- PPAR delta | (E)-2-(4-(Cyclohexyl(((4-methyl-2-(4-(trifluoromethyl)-phenyl)thiazol-5-yl)methoxy)imino)methyl)phenoxy)acetic acid | Drug Info |
| HDAC1 --- HDAC4 | azumamide C | Drug Info |
| Erbeta --- ER | Pipendoxifene | Drug Info |
| PPAR gamma --- PPAR delta | rac-2-(3-((4-tert-butylbenzamido)methyl)-4-methoxybenzyl)butanoic acid | Drug Info |
| HER2 --- MMP-2 | (6S,7S)-N-hydroxy-5-methyl-6-(4-phenylpiperazine-1-carbonyl)-5-azaspiro[2.5]octane-7-carboxamide | Drug Info |
| Erbeta --- ER | 2-(3-Fluoro-phenyl)-1-methyl-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(2-(3-(pyridin-3-yl)prop-2-ynyloxy)-4-((4-(trifluoromethyl)phenoxy)methyl)phenylthio)-5,6,7,8-tetrahydronaphthalen-1-yloxy)acetic acid | Drug Info |
| JAK2 --- CD135 | (R)-3-(6-(1-(4-fluorophenyl)-2-methylpropylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine | Drug Info |
| Erbeta --- ER | SID7967678 | Drug Info |
| PPAR gamma --- PPAR delta | 2-(2,3-dimethyl-4-(2-(pyridin-4-ylmethoxy)-4-((4-(trifluoromethyl)phenoxy)methyl)phenylthio)phenoxy)acetic acid | Drug Info |
| JNK1 --- JNK3 | N6-(4-(methylsulfonyl)benzyl)-4-amino-3-cyano-N2-isopropylpyridine-2,6-dicarboxamide | Drug Info |
| Erbeta --- ER | 5-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-5,11-dihydro-chromeno[4,3-c]chromene-2,8-diol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(3-((4-chloro-2-methylbenzamido)methyl)phenoxy)-2-methylphenoxy)-2-methylpropanoic acid | Drug Info |
| JNK1 --- JNK3 | 5-cyano-N-(2,5-dimethoxybenzyl)-6-ethoxypyridine-2-carboxamide | Drug Info |
| Erbeta --- ER | (2-(3-fluoro-4-hydroxyphenyl)-6-hydroxybenzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone | Drug Info |
| PPAR gamma --- PPAR delta | (S)-2-(3-((benzo[d]oxazol-2-yl(3-phenoxypropyl)amino)methyl)phenoxy)butanoic acid | Drug Info |
| JNK1 --- JNK3 | N-(4,4'-bithiazol-5-yl)-2-(isoquinolin-5-yl)acetamide | Drug Info |
| Erbeta --- ER | (2R,3S)-6-Chloro-3-(4-hydroxy-phenyl)-2-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-2,3-dihydro-benzo[1,4]oxathiin-7-ol | Drug Info |
| PPAR gamma --- PPAR delta | 3-(4-(3-((5-bromo-1H-indole-2-carboxamido)methyl)phenoxy)-2-methylphenyl)propanoic acid | Drug Info |
| JNK1 --- JNK3 | 2-(4-methoxyphenyl)-N-(4-methyl-3-(3-methyl-1H-1,2,4-triazol-5-yl)thiophen-2-yl)acetamide | Drug Info |
| Erbeta --- ER | 1-Chloro-6-(3-chloro-4-hydroxy-phenyl)-naphthalen-2-ol | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-(2-(5-methoxypent-2-ynyloxy)-4-((4-(trifluoromethyl)phenoxy)methyl)phenylthio)-5,6,7,8-tetrahydronaphthalen-1-yloxy)acetic acid | Drug Info |
| JNK1 --- JNK3 | 5-bromo-N-(3-methyl-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)phenyl)furan-2-carboxamide | Drug Info |
| Erbeta --- ER | 1-Methyl-2-phenyl-1-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-1,2,3,4-tetrahydro-isoquinolin-6-ol | Drug Info |
| JNK1 --- JNK3 | 5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin-2-yl)pyrazine-2-carboxamide | Drug Info |
| Erbeta --- ER | 6-(4-(isopropylsulfonyl)phenyl)-5-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)naphthalen-2-ol | Drug Info |
| JNK1 --- JNK3 | 5-methoxy-N-(3-methyl-2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)phenyl)furan-2-carboxamide | Drug Info |
| PPAR gamma --- PPAR delta | 2-(4-((3-(4-tert-butylphenyl)-1-ethyl-1H-pyrazole-5-carboxamido)methyl)-2-methylphenoxy)-2-methylpropanoic acid | Drug Info |
| Erbeta --- ER | 2,2-dimethyl-propionic acid (S)-8-(2,2-dimethyl-propionyloxy)-11-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-5,11-dihydro-chromeno[4,3-c]chromen-2-yl ester | Drug Info |
| JNK1 --- JNK3 | 4-amino-5-chloro-6-isopropoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamide | Drug Info |
| PPAR gamma --- PPAR delta | (S)-3-[4-(3,3-Bis-biphenyl-4-yl-allyloxy)-phenyl]-2-ethoxy-propionic acid | Drug Info |
| Erbeta --- ER | 17alpha-(2,2-Diacetyl-1,3-dihydro-2H-inden-5-yl)-estradiol | Drug Info |
| JNK1 --- JNK3 | methyl 4-methyl-2-(2-(4-(pyridin-4-yl)phenyl)acetamido)thiophene-3-carboxylate | Drug Info |
| PR --- mRNA of AR | 2,2,4-Trimethyl-9-nitro-2,3,4,5-tetrahydro-1H-6-oxa-1-aza-chrysene | Drug Info |
| Erbeta --- ER | 2-(3-Fluoro-4-hydroxy-phenyl)-benzo[b]thiophen-6-ol | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.