TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00933	Histone lysine demethylase PHF8	D0L5WM	Amiodarone	Approved	2157	C25H29I2NO3	645.3	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I	IC50 = 252000 nM	Non binder
T00933	Histone lysine demethylase PHF8	B40XZA	Chembl4127094	Investigative	145961258	C25H32INO3	521.4	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=CC=C3OCCC[N+](C)(C)C.[I-]	IC50 = 496000 nM	Non binder
T00933	Histone lysine demethylase PHF8	B6FJO5	Chembl4129830	Investigative	145960532	C25H30F2INO3	557.4	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)F)OCCC[N+](C)(C)C)F.[I-]	IC50 = 242000 nM	Non binder
T00933	Histone lysine demethylase PHF8	B6GD8S	Chembl4126240	Investigative	70702119	C24H28I3NO3	759.2	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCC[N+](C)(C)C)I.[I-]	IC50 = 307000 nM	Non binder
T00933	Histone lysine demethylase PHF8	B6PSZ9	(2R)-3-(Naphthalen-1-ylmethylsulfanyl)-2-(oxaloamino)propanoic acid	Investigative	56964909	C16H15NO5S	333.4	C1=CC=C2C(=C1)C=CC=C2CSC[C@@H](C(=O)O)NC(=O)C(=O)O	IC50 > 1000000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BBZ6H0	Chembl4126135	Investigative	145963156	C22H25NO3	351.4	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)OCCCN	IC50 = 386000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BBZO35	N-(Carboxycarbonyl)-S-(Naphthalen-2-Ylmethyl)-L-Cysteine	Investigative	56684141	C16H15NO5S	333.4	C1=CC=C2C=C(C=CC2=C1)CSC[C@@H](C(=O)O)NC(=O)C(=O)O	IC50 > 1000000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BCYX23	Chembl4126951	Investigative	145962553	C24H29NO3	379.5	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)OCCCN(C)C	IC50 = 397000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BGA7W6	Chembl4127515	Investigative	145963620	C28H38INO3	563.5	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=C(C=C3)OCCC[N+](CC)(CC)CC.[I-]	IC50 = 221000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BL60AE	Chembl4129540	Investigative	70702121	C25H30I3NO3	773.2	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCC[N+](C)(C)C)I.[I-]	IC50 = 390000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BOWG94	Chembl4128613	Investigative	145962837	C22H26INO3	479.4	CC1=C(C2=CC=CC=C2O1)C(=O)C3=CC=CC=C3OCCC[N+](C)(C)C.[I-]	IC50 = 286000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BTQE05	Chembl4129980	Investigative	145962898	C27H36INO5	581.5	CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)OC)OCCC[N+](C)(C)C)OC.[I-]	IC50 = 240000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BV2W4P	N-(Carboxycarbonyl)-S-(3-Nitrobenzyl)-L-Cysteine	Investigative	56684140	C12H12N2O7S	328.3	C1=CC(=CC(=C1)[N+](=O)[O-])CSC[C@@H](C(=O)O)NC(=O)C(=O)O	IC50 > 1000000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BVKO45	Chembl4127792	Investigative	145963214	C22H26INO2S	495.4	CC1=C(C2=CC=CC=C2S1)C(=O)C3=CC=C(C=C3)OCCC[N+](C)(C)C.[I-]	IC50 = 377000 nM	Non binder
T00933	Histone lysine demethylase PHF8	BW42QB	Chembl4128152	Investigative	145963644	C22H27IN2O2	478.4	CN=C(C1=CC=C(C=C1)OCCC[N+](C)(C)C)C2=COC3=CC=CC=C32.[I-]	IC50 > 300000 nM	Non binder
T00933	Histone lysine demethylase PHF8	D07IOY	Pyridine-2,4-dicarboxylic acid	Investigative	10365	C7H5NO4	167.12	C1=CN=C(C=C1C(=O)O)C(=O)O	IC50 > 250000 nM	Non binder
T00933	Histone lysine demethylase PHF8	D08IZY	2-(carboxymethylamino)-2-oxoacetic acid	Investigative	3080614	C4H5NO5	147.09	C(C(=O)O)NC(=O)C(=O)O	IC50 > 250000 nM	Non binder