TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T03500	Matrix metalloproteinase-12	B0A1MG	[(4S,5S)-2-(4-Bromo-phenyl)-5-vinyl-4,5-dihydro-oxazol-4-yl]-methanol	Investigative	9993891	C12H12BrNO2	282.13	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)Br)CO	Ki > 300000 nM	Non binder
T03500	Matrix metalloproteinase-12	B3K4BP	Chembl4171886	Investigative	145950074	C12H15N3O7S	345.33	CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T03500	Matrix metalloproteinase-12	B9GF6S	8-Chloro-2-methyl-4H-thiochromeno[4,3-c]pyrazole	Investigative	2741314	C11H9ClN2S	236.72	CN1C=C2CSC3=C(C2=N1)C=C(C=C3)Cl	IC50 = 1000000 nM	Non binder
T03500	Matrix metalloproteinase-12	BB98UI	3,2-Diguanidinoneamine	Investigative	23645953	C14H30N8O6	406.44	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N=C(N)N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N=C(N)N)O)O)N	Ki > 300000 nM	Non binder
T03500	Matrix metalloproteinase-12	BEU14G	Chembl4175156	Investigative	145949783	C16H23N3O7S	401.4	CCCCCNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 493250 nM	Non binder
T03500	Matrix metalloproteinase-12	BEUG21	6-(2-Methyl-1,3-thiazol-4-yl)-3,4-dihydro-1H-quinolin-2-one	Investigative	2801266	C13H12N2OS	244.31	CC1=NC(=CS1)C2=CC3=C(C=C2)NC(=O)CC3	IC50 = 5000000 nM	Non binder
T03500	Matrix metalloproteinase-12	BFZ5I0	Chembl4167291	Investigative	145955226	C15H21N3O7S	387.4	CC(C)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T03500	Matrix metalloproteinase-12	BG53LT	6-Methyl-2H-1,4-benzoxazin-3(4H)-one	Investigative	2763839	C9H9NO2	163.17	CC1=CC2=C(C=C1)OCC(=O)N2	IC50 = 355000 nM	Non binder
T03500	Matrix metalloproteinase-12	BGV24B	Neamine guanidinylated deriv. 29	Investigative	23645959	C20H42N12O6	546.6	CO[C@H]1[C@@H](C[C@@H]([C@H]([C@@H]1OC)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN=C(N)N)OC)OC)N=C(N)N)N=C(N)N)N=C(N)N	Ki > 300000 nM	Non binder
T03500	Matrix metalloproteinase-12	BGV36J	(4S,5S)-2-p-Tolyl-5-vinyl-4,5-dihydro-oxazole-4-thiol	Investigative	44394703	C12H13NOS	219.3	CC1=CC=C(C=C1)C2=N[C@H]([C@@H](O2)C=C)S	Ki > 300000 nM	Non binder
T03500	Matrix metalloproteinase-12	BJ0LR6	Thioacetic acid S-[(4S,5S)-2-((E)-styryl)-5-vinyl-4,5-dihydro-oxazol-4-yl] ester	Investigative	44394645	C15H15NO2S	273.4	CC(=O)S[C@H]1[C@@H](OC(=N1)/C=C/C2=CC=CC=C2)C=C	Ki > 300000 nM	Non binder
T03500	Matrix metalloproteinase-12	BK2ZL3	Neamine guanidinylated deriv. 4	Investigative	9957228	C16H34N12O6	490.5	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N=C(N)N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN=C(N)N)O)O)N=C(N)N)O)O)N=C(N)N	Ki > 300000 nM	Non binder
T03500	Matrix metalloproteinase-12	BMDV75	((4S,5S)-2-Phenyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol	Investigative	44394814	C12H13NO2	203.24	C=C[C@H]1[C@@H](N=C(O1)C2=CC=CC=C2)CO	Ki > 2000000 nM	Non binder
T03500	Matrix metalloproteinase-12	BMY37I	Chembl4202548	Investigative	145976989	C22H20O4S2	412.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)SC3=CC=CC=C3C(=O)CS(=O)(=O)C	IC50 = 230000 nM	Non binder
T03500	Matrix metalloproteinase-12	BU89NX	5-Methoxybenzimidazole	Investigative	78598	C8H8N2O	148.16	COC1=CC2=C(C=C1)N=CN2	IC50 = 2000000 nM	Non binder
T03500	Matrix metalloproteinase-12	BW5FE4	1,3,2-Triguanidinoneamine	Investigative	11328354	C15H32N10O6	448.48	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N=C(N)N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N=C(N)N)O)O)N=C(N)N	Ki > 300000 nM	Non binder
T03500	Matrix metalloproteinase-12	BXH05U	Chembl4170455	Investigative	145956298	C14H19N3O7S	373.38	CC(C)NC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)[N+](=O)[O-]	IC50 = 493200 nM	Non binder