TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T03691	Leukotriene A-4 hydrolase	D0U3EP	Resveratrol	Phase 3	445154	C14H12O3	228.24	C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O	IC50 = 212000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B12UFY	Methyl 3-amino-4-phenyl-2-sulfanylbutanoate	Investigative	14186527	C11H15NO2S	225.31	COC(=O)C(C(CC1=CC=CC=C1)N)S	IC50 = 250000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B1V8TO	Methyl (3S)-3-amino-4-phenyl-2-sulfanylbutanoate	Investigative	14186529	C11H15NO2S	225.31	COC(=O)C([C@H](CC1=CC=CC=C1)N)S	IC50 ~ 250000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B31QIB	5-Benzyloxy-DL-tryptophan	Investigative	97908	C18H18N2O3	310.3	C1=CC=C(C=C1)COC2=CC3=C(C=C2)NC=C3CC(C(=O)O)N	IC50 = 231000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B3J4MG	3-Amino-2-mercapto-4-phenyl-butyric acid methyl ester	Investigative	14186530	C11H15NO2S	225.31	COC(=O)C([C@@H](CC1=CC=CC=C1)N)S	IC50 > 250000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B4TZ6X	7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one hydrochloride	Investigative	24988072	C11H14ClNO	211.69	C1CC2=CC=CC=C2CC(=O)C1N.Cl	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B5X6BG	(2R,3S)-Methyl 3-amino-2-hydroxy-4-phenylbutanoate	Investigative	11816616	C11H15NO3	209.24	COC(=O)[C@@H]([C@H](CC1=CC=CC=C1)N)O	IC50 > 500000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B7MR9Q	2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-methyl-pentanoic acid	Investigative	44310154	C16H24N2O3S	324.4	CC(C)C[C@@H](C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)S	IC50 > 250000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B80XFC	1-Aminoindan-2-one hydrochloride	Investigative	53324936	C9H10ClNO	183.63	C1C2=CC=CC=C2C(C1=O)N.Cl	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	B96PXD	(5S,7S)-7-Amino-5-(2-phenylethyl)-5,7,8,9-tetrahydrobenzo[7]annulen-6-one;hydrochloride	Investigative	66560598	C19H22ClNO	315.8	C1CC2=CC=CC=C2[C@@H](C(=O)[C@H]1N)CCC3=CC=CC=C3.Cl	Ki = 470000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BB2CD3	Pyridinium, 4-[(4-nitrophenyl)methyl]-1-(2-oxo-2-phenylethyl)-, bromide	Investigative	44563649	C20H17BrN2O3	413.3	C1=CC=C(C=C1)C(=O)C[N+]2=CC=C(C=C2)CC3=CC=C(C=C3)[N+](=O)[O-].[Br-]	IC50 = 386000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BG8Y6D	6-Amino-5,6,8,9-tetrahydrobenzo[7]annulen-7-one;hydrochloride	Investigative	53320959	C11H14ClNO	211.69	C1CC(=O)C(CC2=CC=CC=C21)N.Cl	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BG91RU	5-Fluoroindole	Investigative	67861	C8H6FN	135.14	C1=CC2=C(C=CN2)C=C1F	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BI0SH5	3,3-Difluoro-4-oxo-4-(5-methyl-1H-imidazol-4-yl)butanoic acid ethyl ester	Investigative	10060458	C10H12F2N2O3	246.21	CCOC(=O)CC(C(=O)C1=C(NC=N1)C)(F)F	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BI8J7L	5-(2-(Pyrrolidin-1-yl)ethoxy)-1H-indole	Investigative	22139205	C14H18N2O	230.31	C1CCN(C1)CCOC2=CC3=C(C=C2)NC=C3	IC50 = 234000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BK3L5Y	3-Amino-3,4-dihydro-2-(1H)-naphthalenone, hydrochloride	Investigative	24901452	C10H12ClNO	197.66	C1C(C(=O)CC2=CC=CC=C21)N.Cl	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BKS7C4	1-[2-(1H-Indol-5-yloxy)ethyl]piperidine-4-carboxylic acid	Investigative	44129622	C16H20N2O3	288.34	C1CN(CCC1C(=O)O)CCOC2=CC3=C(C=C2)NC=C3	IC50 = 966000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BL17AG	(5S,7S)-7-Amino-5-fluoro-5,7,8,9-tetrahydrobenzo[7]annulen-6-one;hydrochloride	Investigative	66560594	C11H13ClFNO	229.68	C1CC2=CC=CC=C2[C@@H](C(=O)[C@H]1N)F.Cl	Ki > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BSD2T0	5-Chloroindole	Investigative	87110	C8H6ClN	151.59	C1=CC2=C(C=CN2)C=C1Cl	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BT9FN0	3,3-Difluoro-4-oxo-6-phenyl-5-hexenoic acid ethyl ester	Investigative	10084376	C14H14F2O3	268.26	CCOC(=O)CC(C(=O)/C=C/C1=CC=CC=C1)(F)F	IC50 > 5000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BV5UP9	(7S)-7-Amino-5,7,8,9-tetrahydrobenzo[7]annulen-6-one;hydrochloride	Investigative	71453803	C11H14ClNO	211.69	C1CC2=CC=CC=C2CC(=O)[C@H]1N.Cl	Ki > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BV62SB	2-(Pyridin-3-ylmethoxy)aniline	Investigative	8027171	C12H12N2O	200.24	C1=CC=C(C(=C1)N)OCC2=CN=CC=C2	IC50 > 2000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	BYM63J	(2S,3S)-3-Amino-2-hydroxy-4-phenylbutanoic acid	Investigative	2762293	C10H13NO3	195.21	C1=CC=C(C=C1)C[C@@H]([C@@H](C(=O)O)O)N	IC50 > 1000000 nM	Non binder
T03691	Leukotriene A-4 hydrolase	D00EJS	5-hydroxyindole	Investigative	16054	C8H7NO	133.15	C1=CC2=C(C=CN2)C=C1O	IC50 > 1000000 nM	Non binder