TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T05114 Chymase B0VB9W 6-Chloroindole Investigative 87111 C8H6ClN 151.59 C1=CC(=CC2=C1C=CN2)Cl IC50 = 340000 nM Non binder T05114 Chymase B2Z8MG 4-Chloroindolin-2-One Investigative 1480686 C8H6ClNO 167.59 C1C2=C(C=CC=C2Cl)NC1=O IC50 > 1000000 nM Non binder T05114 Chymase B3IEL8 6-Chloroisoindolin-1-one Investigative 12496475 C8H6ClNO 167.59 C1C2=C(C=C(C=C2)Cl)C(=O)N1 IC50 > 1000000 nM Non binder T05114 Chymase B3S4MT 6-Chlorooxindole Investigative 736344 C8H6ClNO 167.59 C1C2=C(C=C(C=C2)Cl)NC1=O IC50 = 470000 nM Non binder T05114 Chymase B3S7IO 6-Chloro-1-methylindolin-2-one Investigative 10058155 C9H8ClNO 181.62 CN1C(=O)CC2=C1C=C(C=C2)Cl IC50 > 1000000 nM Non binder T05114 Chymase B9KI4M 2-(1-Methoxyethylidene)-4-cyclopentene-1,3-dione Investigative 21953543 C8H8O3 152.15 CC(=C1C(=O)C=CC1=O)OC IC50 > 1000000 nM Non binder T05114 Chymase BFM5W3 Vaborbactam Investigative 56649692 C12H16BNO5S 297.14 B1([C@H](CC[C@H](O1)CC(=O)O)NC(=O)CC2=CC=CS2)O IC50 > 1000000 nM Non binder T05114 Chymase BKXL90 Oxindole Investigative 321710 C8H7NO 133.15 C1C2=CC=CC=C2NC1=O IC50 > 1000000 nM Non binder T05114 Chymase BNW5H8 7-Chloroindolin-2-one Investigative 3731010 C8H6ClNO 167.59 C1C2=C(C(=CC=C2)Cl)NC1=O IC50 > 1000000 nM Non binder T05114 Chymase BOUM73 6-Bromooxindole Investigative 2773289 C8H6BrNO 212.04 C1C2=C(C=C(C=C2)Br)NC1=O IC50 = 570000 nM Non binder T05114 Chymase BR30EZ 4-Phenyl-2-phenylcarboxamidopentanoic anhydride Investigative 44355100 C36H36N2O5 576.7 C1=CC=C(C=C1)CCC(CC(=O)OC(=O)CC(CCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3)NC(=O)C4=CC=CC=C4 IC50 > 1000000 nM Non binder T05114 Chymase BSA2E0 5-Chlorooxindole Investigative 152801 C8H6ClNO 167.59 C1C2=C(C=CC(=C2)Cl)NC1=O IC50 > 1000000 nM Non binder T05114 Chymase BXE4I2 (S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-heptanoylamino]-3-phenyl-propionic acid ethyl ester Investigative 10504812 C28H35N3O4 477.6 CCCCC(C(C)(C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)OCC)NC(=O)C2=CC=C(C=C2)C#N IC50 = 510000 nM Non binder