TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T11241	Sphingosine-1-phosphate receptor 3	B2J1CB	1-[[4-[5-[Butyl-(2-methoxybenzoyl)amino]-1,3,4-thiadiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid	Investigative	45377938	C25H28N4O4S	480.6	CCCCN(C1=NN=C(S1)C2=CC=C(C=C2)CN3CC(C3)C(=O)O)C(=O)C4=CC=CC=C4OC	EC50 = 427000 nM	Non binder
T11241	Sphingosine-1-phosphate receptor 3	B39NTV	1-[[4-[5-[Butyl-(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid	Investigative	58390822	C25H28N4O3S	464.6	CCCCN(C1=NN=C(S1)C2=CC=C(C=C2)CN3CC(C3)C(=O)O)C(=O)CC4=CC=CC=C4	EC50 = 720000 nM	Non binder
T11241	Sphingosine-1-phosphate receptor 3	B3U2PR	6-(Cyclohexyl(cyclopropylmethyl)amino)-N-(4-((dimethylamino)methyl)phenyl)pyrimidine-4-carboxamide	Investigative	25182921	C24H33N5O	407.6	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC(=NC=N2)N(CC3CC3)C4CCCCC4	EC50 = 1014000 nM	Non binder
T11241	Sphingosine-1-phosphate receptor 3	B96HXU	2-({4-[({6-[Cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]benzyl}amino)butanoic acid	Investigative	25182924	C26H35N5O3	465.6	CCC(C(=O)O)NCC1=CC=C(C=C1)NC(=O)C2=CC(=NC=N2)N(CC3CC3)C4CCCCC4	EC50 = 4890000 nM	Non binder
T11241	Sphingosine-1-phosphate receptor 3	BE38VM	3-(4-(6-(Cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)benzylamino)propanoic acid	Investigative	25182926	C25H33N5O3	451.6	C1CCC(CC1)N(CC2CC2)C3=NC=NC(=C3)C(=O)NC4=CC=C(C=C4)CNCCC(=O)O	EC50 = 1094000 nM	Non binder
T11241	Sphingosine-1-phosphate receptor 3	BE85IJ	1-[[4-[5-[Benzoyl(butyl)amino]-1,3,4-thiadiazol-2-yl]phenyl]methyl]azetidine-3-carboxylic acid	Investigative	45377248	C24H26N4O3S	450.6	CCCCN(C1=NN=C(S1)C2=CC=C(C=C2)CN3CC(C3)C(=O)O)C(=O)C4=CC=CC=C4	EC50 = 400000 nM	Non binder