TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T11793	Cytochrome P450 2B6	B04OQB	1-(1-(2-(Pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)-4-(4-(trifluoromethyl)phenyl)pyridin-2(1H)-one	Investigative	25205318	C25H23F3N4O	452.5	C1CCN(C1)CCN2C3=C(C=C(C=C3)N4C=CC(=CC4=O)C5=CC=C(C=C5)C(F)(F)F)C=N2	IC50 > 10000000 nM	Non binder
T11793	Cytochrome P450 2B6	B0YA2H	Pyridine, 3-(4-methyl-1H-imidazol-1-yl)-	Investigative	44388612	C9H9N3	159.19	CC1=CN(C=N1)C2=CN=CC=C2	IC50 > 300000 nM	Non binder
T11793	Cytochrome P450 2B6	B5AQ2J	(NE)-N-[(5-pyridin-3-ylfuran-2-yl)methylidene]hydroxylamine;(NZ)-N-[(5-pyridin-3-ylfuran-2-yl)methylidene]hydroxylamine	Investigative	56679632	C20H16N4O4	376.4	C1=CC(=CN=C1)C2=CC=C(O2)/C=N/O.C1=CC(=CN=C1)C2=CC=C(O2)/C=N\\O	IC50 = 206000 nM	Non binder
T11793	Cytochrome P450 2B6	B5KS2N	Chembl4170930	Investigative	145951998	C13H14Cl3N3	318.6	C1=CC(=CN=C1)C2=C(C=NC=C2)C#CCN.Cl.Cl.Cl	IC50 = 364000 nM	Non binder
T11793	Cytochrome P450 2B6	B8E2AM	1-(5-(Pyridin-3-yl)thiophen-2-yl)ethan-1-one	Investigative	15778480	C11H9NOS	203.26	CC(=O)C1=CC=C(S1)C2=CN=CC=C2	IC50 = 217000 nM	Non binder
T11793	Cytochrome P450 2B6	B8YKP1	(5-Pyridin-3-ylthiophen-2-yl)methanamine;(5-pyridin-3-ylthiophen-2-yl)methanimine	Investigative	44388657	C30H26N6S3	566.8	C1=CC(=CN=C1)C2=CC=C(S2)CN.C1=CC(=CN=C1)C2=CC=C(S2)C=N.C1=CC(=CN=C1)C2=CC=C(S2)C=N	IC50 = 256000 nM	Non binder
T11793	Cytochrome P450 2B6	B98UHN	N,N-Dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine	Investigative	11171679	C12H14N2O	202.25	CN(C)CC1=CC=C(O1)C2=CN=CC=C2	Ki > 400000 nM	Non binder
T11793	Cytochrome P450 2B6	BBVS73	1-[1-(4-Cyanophenyl)-4-bicyclo[3.1.0]hexanyl]-3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[3-(4-methylpiperazin-1-yl)propyl]urea	Investigative	52948857	C29H33F4N5O	543.6	CN1CCN(CC1)CCCN(C2CCC3(C2C3)C4=CC=C(C=C4)C#N)C(=O)NC5=CC(=C(C=C5)F)C(F)(F)F	IC50 > 10000000 nM	Non binder
T11793	Cytochrome P450 2B6	BN04HS	Dimethyl({[5-(pyridin-3-yl)thiophen-2-yl]methyl})amine	Investigative	11310529	C12H14N2S	218.32	CN(C)CC1=CC=C(S1)C2=CN=CC=C2	Ki > 400000 nM	Non binder
T11793	Cytochrome P450 2B6	BOWV70	4-(2,4-Dichlorophenyl)-1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)pyridin-2(1H)-one	Investigative	25205319	C24H22Cl2N4O	453.4	C1CCN(C1)CCN2C3=C(C=C(C=C3)N4C=CC(=CC4=O)C5=C(C=C(C=C5)Cl)Cl)C=N2	IC50 > 10000000 nM	Non binder
T11793	Cytochrome P450 2B6	BPKY46	3-(2-Methyl-1H-imidazol-1-yl)pyridine	Investigative	16654686	C9H9N3	159.19	CC1=NC=CN1C2=CN=CC=C2	Ki > 300000 nM	Non binder
T11793	Cytochrome P450 2B6	BSEF80	Auglurant	Investigative	60168069	C16H12FN5O2	325.3	CC1=CC(=CC(=N1)C(=O)NC2=NC=C(C=C2)F)OC3=CN=CN=C3	IC50 > 200000 nM	Non binder
T11793	Cytochrome P450 2B6	BV1B3U	5-Hydroxy saxagliptin	Investigative	23645678	C18H25N3O3	331.4	C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)(CC(C5)(C4)O)O)N	IC50 > 200000 nM	Non binder
T11793	Cytochrome P450 2B6	BV8YP7	3-(Pyridin-3-yl)propan-1-amine	Investigative	13557523	C8H12N2	136.19	C1=CC(=CN=C1)CCCN	Ki > 400000 nM	Non binder
T11793	Cytochrome P450 2B6	BZD2G7	N-Methyl-(5-pyrid-3-ylthien-2-yl)methylamine	Investigative	11321674	C11H12N2S	204.29	CNCC1=CC=C(S1)C2=CN=CC=C2	Ki > 400000 nM	Non binder
T11793	Cytochrome P450 2B6	D00AWM	GW803430	Investigative	9826520	C25H24ClN3O3S	482	COC1=C(C=CC(=C1)N2C=NC3=C(C2=O)SC(=C3)C4=CC=C(C=C4)Cl)OCCN5CCCC5	IC50 > 10000000 nM	Non binder