TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T17758	Urokinase-type plasminogen activator	B08LHB	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127046388	C26H28FN7O3	505.5	C[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)F	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B0B7FQ	3-(4-Amidinophenyl)-2-[[[(4-amidinophenylsulfonyl)amino]acetyl]amino]propionic acid	Investigative	10095093	C19H22N6O5S	446.5	C1=CC(=CC=C1CC(C(=O)O)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=N)N)C(=N)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B0B7ZQ	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-sulfamoylphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655489	C24H27N9O5S	553.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)S(=O)(=O)N	IC50 > 400000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B0IK7T	2-Chloro-benzenesulfonic acid 3-(3-guanidino-propoxy)-5-methyl-phenyl ester	Investigative	44287937	C17H20ClN3O4S	397.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCCCN=C(N)N	Ki > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B0LT9N	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655486	C24H25FN8O3	492.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)F	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B0LX3C	N-[4-(Aminomethyl)cyclohexyl]imidazo[1,2-a]pyridin-3-amine	Investigative	127041062	C14H20N4	244.34	C1CC(CCC1CN)NC2=CN=C3N2C=CC=C3	IC50 = 500000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B0TDN5	2-[[6-Amino-5-[(Z)-N'-hydroxycarbamimidoyl]pyrazin-2-yl]amino]acetic acid	Investigative	136264091	C7H10N6O3	226.19	C1=C(N=C(C(=N1)/C(=N/O)/N)N)NCC(=O)O	IC50 = 279000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B1DA4C	3-(3-Amidinophenyl)-2-[[[(4-thiocarbamoylphenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	10624948	C21H25N5O5S2	491.6	CCOC(=O)C(CC1=CC(=CC=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=S)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B1GUP7	Mupain-1	Investigative	101862198	C51H73N13O16S2	1188.3	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)N)C(=O)O)CC(=O)O)CC(C)C)CC3=CC=C(C=C3)O)CCCN=C(N)N)CO)CC4=CC=C(C=C4)O	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B1U8JQ	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(cyanomethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655497	C26H27N9O4	529.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OCC#N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B24EPB	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-[4-(2-oxopropoxy)phenyl]imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655495	C27H30N8O5	546.6	CC(=O)COC1=CC=C(C=C1)N2CC(=O)N(C2=O)CC3=CC4=CN=C(N=C4N3C)C(=O)N[C@@H](CCCCN)C#N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B26BID	3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(4-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide	Investigative	44569333	C26H38N6O4S	530.7	C1CN(CCC1CCN)C(=O)[C@H](CC2=CC=C(C=C2)CN)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B29NSR	3,5-Diamino-6-chloropyrazine-2-carbohydrazide	Investigative	12319196	C5H7ClN6O	202.6	C1(=C(N=C(C(=N1)Cl)N)N)C(=O)NN	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B2FL3D	2-Chlorobenzenesulfonic acid 3-methyl-5-(1-amidinopiperidine-4-ylmethoxy)phenyl ester	Investigative	9910982	C20H24ClN3O4S	437.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCC3CCN(CC3)C(=N)N	Ki > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B2JKZ7	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-fluorophenyl)-5-oxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655504	C24H27FN8O2	478.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3CN(CC3=O)C4=CC=C(C=C4)F	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B2LT3J	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-cyanophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655491	C25H25N9O3	499.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)C#N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B32QRU	4-[4-(3-Bromophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537241	C15H12BrN3S3	410.4	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC(=CC=C3)Br	Ki = 442000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B3BUP0	4-Amino-5-chloro-N-(diaminomethylidene)-2-methoxybenzamide;hydrochloride	Investigative	57391009	C9H12Cl2N4O2	279.12	COC1=CC(=C(C=C1C(=O)N=C(N)N)Cl)N.Cl	IC50 > 222000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B3QM2X	2-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]ethylphosphonic acid;hydrochloride	Investigative	57397992	C8H14Cl2N7O4P	374.12	C(CP(=O)(O)O)NC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B3RIU8	3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(3-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide	Investigative	44569301	C26H38N6O4S	530.7	C1CN(CCC1CCN)C(=O)[C@H](CC2=CC(=CC=C2)CN)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B3SWT2	5-Methylsulfanyl-4-[4-(4-p-tolylsulfamoyl-phenyl)-thiazol-2-yl]-thiophene-2-carboxamidine	Investigative	44278528	C22H20N4O2S4	500.7	CC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)C3=CSC(=N3)C4=C(SC(=C4)C(=N)N)SC	Ki = 272000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B40FGY	Imidazo[1,2-a]pyridin-3-amine,n-[4-(aminomethyl)phenyl]-	Investigative	76849444	C14H14N4	238.29	C1=CC2=NC=C(N2C=C1)NC3=CC=C(C=C3)CN	IC50 > 500000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B4FHC9	3-(3-Amino-1,2,4-oxadiazol-5-yl)-5-chloro-2,6-pyrazinediamine	Investigative	194530	C6H6ClN7O	227.61	C1(=C(N=C(C(=N1)Cl)N)N)C2=NC(=NO2)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B4W9GM	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylpropyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127045986	C34H37N7O4	607.7	CC(C)[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B4X7WA	Ethyl 4-[[4-[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoate	Investigative	127036010	C35H51N3O5	593.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=C(C=C2)C(=O)OCC)NC(=O)C3CCC(CC3)CN	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B53HYV	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127046390	C31H32N8O4	580.6	C[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=NC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B56HKW	3-[4-[(6-Cyanonaphthalene-2-carbonyl)amino]phenyl]benzoic acid	Investigative	57401326	C25H16N2O3	392.4	C1=CC(=CC(=C1)C(=O)O)C2=CC=C(C=C2)NC(=O)C3=CC4=C(C=C3)C=C(C=C4)C#N	IC50 > 250000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B5YW4G	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-4-(4-phenoxyphenyl)piperazin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655506	C31H32N8O4	580.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3CC(=O)N(CC3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B60PIX	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	122179842	C29H29N9O4	567.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=NC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B63KVF	4-(4-Cyclohexyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537290	C15H19N3S3	337.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3CCCCC3	Ki = 641000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B68UPA	5-Methylsulfanyl-4-(4-o-tolyl-thiazol-2-yl)-thiophene-2-carboxamidine	Investigative	18536877	C16H15N3S3	345.5	CC1=CC=CC=C1C2=CSC(=N2)C3=C(SC(=C3)C(=N)N)SC	Ki = 277000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B6CMA3	2-Chloro-benzenesulfonic acid 3-(1-carbamimidoyl-piperidin-3-ylmethoxy)-5-methyl-phenyl ester	Investigative	44287798	C20H24ClN3O4S	437.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCC3CCCN(C3)C(=N)N	Ki > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B6F2XR	Amino(picolinamido)methaniminium chloride	Investigative	57394527	C7H9ClN4O	200.62	C1=CC=NC(=C1)C(=O)N=C(N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B6PT7Z	N-[4-(2-Aminoethoxy)phenyl]imidazo[1,2-a]pyridin-3-amine	Investigative	127040830	C15H16N4O	268.31	C1=CC2=NC=C(N2C=C1)NC3=CC=C(C=C3)OCCN	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B6QIS4	Benzoylguanidine hydrochloride	Investigative	45050329	C8H10ClN3O	199.64	C1=CC=C(C=C1)C(=O)N=C(N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B72ERJ	2-[(6-Amino-5-carbamimidoyl-3-chloropyrazin-2-yl)amino]acetic acid	Investigative	70693724	C7H9ClN6O2	244.64	C(C(=O)O)NC1=NC(=C(N=C1Cl)C(=N)N)N	IC50 = 237000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B7RI4S	2-[(6-Amino-5-carbamimidoylpyrazin-2-yl)amino]acetic acid	Investigative	70683232	C7H10N6O2	210.19	C1=C(N=C(C(=N1)C(=N)N)N)NCC(=O)O	IC50 = 212000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B7V1HR	4-(4-Phenyl-5-methyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537258	C16H15N3S3	345.5	CC1=C(N=C(S1)C2=C(SC(=C2)C(=N)N)SC)C3=CC=CC=C3	Ki = 305000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B8V5RY	Methyl 2-[[4-[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-(octylamino)-3-oxopropyl]phenoxy]methyl]benzoate	Investigative	127035842	C34H49N3O5	579.8	CCCCCCCCNC(=O)[C@H](CC1=CC=C(C=C1)OCC2=CC=CC=C2C(=O)OC)NC(=O)C3CCC(CC3)CN	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B95KUD	3-(4-Guanidinophenyl)acrylic acid	Investigative	22098976	C10H11N3O2	205.21	C1=CC(=CC=C1/C=C/C(=O)O)N=C(N)N	Ki = 1318256.74 nM	Non binder
T17758	Urokinase-type plasminogen activator	B97YHM	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(2-carbamoylphenoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655501	C31H31N9O5	609.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5C(=O)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B9FT3D	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(4-methoxyphenoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655498	C31H32N8O5	596.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=C(C=C5)OC	IC50 > 400000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B9K5NJ	3-Benzoyl-1H-indole-6-carboxamidine	Investigative	44331672	C16H13N3O	263.29	C1=CC=C(C=C1)C(=O)C2=CNC3=C2C=CC(=C3)C(=N)N	Ki = 267000 nM	Non binder
T17758	Urokinase-type plasminogen activator	B9OGL5	(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-23-benzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-11-(1H-indol-3-ylmethyl)-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid	Investigative	127037264	C58H85N17O11S2	1260.5	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)N)C(=O)O)CC3=CNC4=CC=CC=C43)CC(C)C)C)CC5CCN(CC5)C(=N)N)CC6=CC=CC=C6)CCCN=C(N)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BA0CY1	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(3-sulfamoylphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655492	C24H27N9O5S	553.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC(=CC=C4)S(=O)(=O)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BA95HB	(2S)-1-[(2R)-2-Amino-3,3-diphenylpropanoyl]-N-[1-(diaminomethylideneamino)-5,8-dioxo-8-piperidin-1-yloctan-4-yl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid	Investigative	49859964	C38H49F6N7O8	845.8	C1CCN(CC1)C(=O)CCC(=O)C(CCCN=C(N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O	Ki = 494000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BAI5R0	N-(Diaminomethylidene)-1H-imidazole-5-carboxamide;hydrochloride	Investigative	57401494	C5H8ClN5O	189.6	C1=C(NC=N1)C(=O)N=C(N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BARC31	N-[(1S)-5-Amino-1-cyanopentyl]-7-methyl-6-[[5-oxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]methyl]pyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655505	C30H32N8O3	552.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3CN(CC3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BB1HF4	3-Amino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride	Investigative	57391005	C6H8Cl2N6O	251.07	C1=C(N=C(C(=N1)N)C(=O)N=C(N)N)Cl.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BB8H9Y	3-(4-Amidinophenyl)-2-[[[(4-amidinophenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	10435038	C21H26N6O5S	474.5	CCOC(=O)C(CC1=CC=C(C=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=N)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BBE18V	4-(4-Benzyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537194	C16H15N3S3	345.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)CC3=CC=CC=C3	Ki = 470000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BBSQ65	2-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]ethanesulfonic acid;hydrochloride	Investigative	57396268	C8H13Cl2N7O4S	374.2	C(CS(=O)(=O)O)NC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BCI36R	N-(Diaminomethylidene)pyrazine-2-carboxamide;hydrochloride	Investigative	57403250	C6H8ClN5O	201.61	C1=CN=C(C=N1)C(=O)N=C(N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BCQ7W0	4-[4-(2,4-Dichlorophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	9908936	C15H11Cl2N3S3	400.4	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=C(C=C(C=C3)Cl)Cl	Ki = 287000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BCYU95	1-(4-Methoxyphenyl)guanidine	Investigative	3621644	C8H11N3O	165.19	COC1=CC=C(C=C1)N=C(N)N	Ki = 676000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BD51OG	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127046555	C31H32N8O4	580.6	C[C@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=NC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BD5KI2	[4-(4-Aminobutyl)-3,6,9-trioxo-2,5,8-triazabicyclo[8.3.1]tetradeca-1(14),10,12-trien-11-yl]methyl-methyl-phenylsulfanium;bromide	Investigative	45266265	C23H29BrN4O3S	521.5	C[S+](CC1=C2C=C(C=C1)NC(=O)C(NC(=O)CNC2=O)CCCCN)C3=CC=CC=C3.[Br-]	Ki = 500000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BD7M3X	3-(3-Amidinophenyl)-2-[[[(4-cyanophenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	11798089	C21H23N5O5S	457.5	CCOC(=O)C(CC1=CC(=CC=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C#N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BD8A6V	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-quinolin-6-yloxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655500	C33H31N9O4	617.7	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC6=C(C=C5)N=CC=C6	IC50 > 400000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BDBR36	N-[(1S)-5-Amino-1-cyanopentyl]-2-[[2,5-dioxo-3-(4-pyridin-4-yloxyphenyl)imidazolidin-1-yl]methyl]-3-methylbenzimidazole-5-carboxamide	Investigative	122179843	C30H30N8O4	566.6	CN1C2=C(C=CC(=C2)C(=O)N[C@@H](CCCCN)C#N)N=C1CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=NC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BE49NM	2-[4-[[(2-Piperidin-4-ylimidazo[1,2-a]pyridin-3-yl)amino]methyl]phenyl]guanidine	Investigative	127040836	C20H25N7	363.5	C1CNCCC1C2=C(N3C=CC=CC3=N2)NCC4=CC=C(C=C4)N=C(N)N	IC50 = 250000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BEC0I4	2-Chlorobenzenesulfonic acid 3-methyl-5-(4-guanidinobutoxy)phenyl ester	Investigative	44288029	C18H22ClN3O4S	411.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCCCCN=C(N)N	Ki > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BF1A5S	(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-11,23-dibenzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid	Investigative	127036086	C56H84N16O11S2	1221.5	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)N)C(=O)O)CC3=CC=CC=C3)CC(C)C)C)CC4CCN(CC4)C(=N)N)CC5=CC=CC=C5)CCCN=C(N)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BFI6V2	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R,2R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylbutyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127045988	C35H39N7O4	621.7	CC[C@@H](C)[C@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BFJV59	2-[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]ethyl-ethoxyphosphinic acid;hydrochloride	Investigative	57396184	C10H18Cl2N7O4P	402.17	CCOP(=O)(CCNC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)O.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BFM5W3	Vaborbactam	Investigative	56649692	C12H16BNO5S	297.14	B1([C@H](CC[C@H](O1)CC(=O)O)NC(=O)CC2=CC=CS2)O	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BG24AR	N-Quinolin-2-yl-guanidine	Investigative	21705171	C10H10N4	186.21	C1=CC=C2C(=C1)C=CC(=N2)N=C(N)N	Ki = 209000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BH3J8Q	4-[4-(4-Nitrophenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18536922	C15H12N4O2S3	376.5	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC=C(C=C3)[N+](=O)[O-]	Ki = 270000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BH74FD	Methyl 4-[(diaminomethylidene)amino]benzoate	Investigative	14346967	C9H11N3O2	193.2	COC(=O)C1=CC=C(C=C1)N=C(N)N	Ki = 1448771.85 nM	Non binder
T17758	Urokinase-type plasminogen activator	BI1Q0E	4-[4-(4-Methoxyphenyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537037	C16H15N3OS3	361.5	COC1=CC=C(C=C1)C2=CSC(=N2)C3=C(SC(=C3)C(=N)N)SC	Ki = 327000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BIQ32L	Guanidine, (aminophenyl)-	Investigative	21434854	C7H10N4	150.18	C1=CC=C(C(=C1)N)N=C(N)N	Ki = 388000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BJ8H4F	N-o-Tolyl-guanidine	Investigative	409363	C8H11N3	149.19	CC1=CC=CC=C1N=C(N)N	Ki = 258821.29 nM	Non binder
T17758	Urokinase-type plasminogen activator	BJM6H2	[1-[(Benzyloxycarbonyl)amino]-4-aminobutyl]phosphonic acid diphenyl ester	Investigative	10895700	C24H27N2O5P	454.5	C1=CC=C(C=C1)COC(=O)NC(CCCN)P(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3	IC50 > 250000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BK2PW0	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(3-carbamoyl-4-phenoxyphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655502	C31H31N9O5	609.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC(=C(C=C4)OC5=CC=CC=C5)C(=O)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BK2Q5E	5,6-Dichloro-N-(diaminomethylidene)pyridine-3-carboxamide;hydrochloride	Investigative	57392805	C7H7Cl3N4O	269.5	C1=C(C=NC(=C1Cl)Cl)C(=O)N=C(N)N.Cl	IC50 = 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BK7N4X	2-Chlorophenyl[3-[2-[methyl(4-pyridyl)amino]ethoxy]-5-methylphenoxy] sulfone	Investigative	10094378	C21H21ClN2O4S	432.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCCN(C)C3=CC=NC=C3	Ki > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BLAG70	4-(4,5-Diphenyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537081	C21H17N3S3	407.6	CSC1=C(C=C(S1)C(=N)N)C2=NC(=C(S2)C3=CC=CC=C3)C4=CC=CC=C4	Ki = 982000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BLB6J5	N-[4-(2-Aminoethoxy)-3,5-dichlorophenyl]imidazo[1,2-a]pyridin-3-amine	Investigative	127040831	C15H14Cl2N4O	337.2	C1=CC2=NC=C(N2C=C1)NC3=CC(=C(C(=C3)Cl)OCCN)Cl	IC50 = 500000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BMIN51	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(3-carbamoylphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655493	C25H27N9O4	517.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=CC(=C4)C(=O)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BNP38W	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[3-carbamoyl-4-(pyridin-4-ylmethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655503	C31H32N10O5	624.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC(=C(C=C4)OCC5=CC=NC=C5)C(=O)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BO8Y3Z	N-[(1S)-5-Amino-1-cyanopentyl]-2-[[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-3-methylbenzimidazole-5-carboxamide	Investigative	122179839	C25H26FN7O3	491.5	CN1C2=C(C=CC(=C2)C(=O)N[C@@H](CCCCN)C#N)N=C1CN3C(=O)CN(C3=O)C4=CC=C(C=C4)F	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BP02UV	3-(3-Amidinophenyl)-2-[[[(4-amidinophenylsulfonyl)amino]acetyl]amino]propionic acid	Investigative	10718240	C19H22N6O5S	446.5	C1=CC(=CC(=C1)C(=N)N)CC(C(=O)O)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=N)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BP3MV4	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-methoxyphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655487	C25H28N8O4	504.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BP6EM8	N-Methyl-2-[[[[(2-naphthyl)sulfonyl]amino]acetyl]amino]-3-[3-(diaminomethyl)phenyl]propanamide	Investigative	44367355	C23H27N5O4S	469.6	CNC(=O)C(CC1=CC(=CC=C1)C(N)N)NC(=O)CNS(=O)(=O)C2=CC3=CC=CC=C3C=C2	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BP9GX7	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(4-carbamoylphenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655490	C25H27N9O4	517.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)C(=O)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BPAD98	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	86302628	C30H30N8O4	566.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BPH2R4	Chembl4127452	Investigative	145961084	C22H25F3N4O3S	482.5	C1CCC(CC1)[C@H](C(=O)NC2=CC=C(C=C2)C(=N)N)NS(=O)(=O)C3=CC=C(C=C3)C(F)(F)F	IC50 > 1946000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BQLT56	Cyanopeptolin 1020	Investigative	46830813; 75297028	C50H72N10O13	1021.2	CCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H]1[C@H](OC(=O)[C@@H](NC(=O)[C@@H](N(C(=O)[C@@H](N2[C@@H](CC[C@@H](C2=O)NC(=O)[C@@H](NC1=O)CCCN=C(N)N)O)CC3=CC=CC=C3)C)CC4=CC=C(C=C4)O)C(C)C)C	IC50 > 605000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BQT31C	2-[[6-Amino-3-chloro-5-[(Z)-N'-hydroxycarbamimidoyl]pyrazin-2-yl]amino]acetic acid	Investigative	136268735	C7H9ClN6O3	260.64	C(C(=O)O)NC1=NC(=C(N=C1Cl)/C(=N/O)/N)N	IC50 = 231000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BR3EK0	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1S)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127046556	C32H33N7O4	579.6	C[C@@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BR92BG	4-(4-Methyl-2-thiazolyl)-5-(methylthio)thiophene-2-carboxamidine	Investigative	9903519	C10H11N3S3	269.4	CC1=CSC(=N1)C2=C(SC(=C2)C(=N)N)SC	Ki = 815000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BRI3D9	5-Methylsulfanyl-4-(4-m-tolyl-thiazol-2-yl)-thiophene-2-carboxamidine	Investigative	18537029	C16H15N3S3	345.5	CC1=CC(=CC=C1)C2=CSC(=N2)C3=C(SC(=C3)C(=N)N)SC	Ki = 546000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BRT12F	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-(4-propylphenyl)imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655488	C27H32N8O3	516.6	CCCC1=CC=C(C=C1)N2CC(=O)N(C2=O)CC3=CC4=CN=C(N=C4N3C)C(=O)N[C@@H](CCCCN)C#N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BRWO92	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[2,5-dioxo-3-[4-(pyridin-4-ylmethoxy)phenyl]imidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655499	C30H31N9O4	581.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OCC5=CC=NC=C5	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BRY9Q3	(3R,8S,11S,14S,17S,20S,23S,26S,29S,32S)-11-(4-Acetamidobutyl)-3-amino-23-benzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17,29-dimethyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid	Investigative	127035685	C55H89N17O12S2	1244.5	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)N)C(=O)O)CCCCNC(=O)C)CC(C)C)C)CC3CCN(CC3)C(=N)N)CC4=CC=CC=C4)CCCN=C(N)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BSG4E9	4-Guanidinobenzoic acid	Investigative	159772	C8H9N3O2	179.18	C1=CC(=CC=C1C(=O)O)N=C(N)N	Ki = 744731.97 nM	Non binder
T17758	Urokinase-type plasminogen activator	BSN52I	N-[3-(Trifluoromethyl)phenyl]guanidine	Investigative	5173985	C8H8F3N3	203.16	C1=CC(=CC(=C1)N=C(N)N)C(F)(F)F	Ki = 418793.57 nM	Non binder
T17758	Urokinase-type plasminogen activator	BTO1B7	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]-2-methylpropyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127045987	C34H37N7O4	607.7	CC(C)[C@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BU03IP	4-[4-(4-Biphenylyl)-2-thiazolyl]-5-(methylthio)thiophene-2-carboxamidine	Investigative	18537184	C21H17N3S3	407.6	CSC1=C(C=C(S1)C(=N)N)C2=NC(=CS2)C3=CC=C(C=C3)C4=CC=CC=C4	Ki = 1740000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BU2T4G	2-Chloro-benzenesulfonic acid 3-(5-guanidino-pentyloxy)-5-methyl-phenyl ester	Investigative	44287797	C19H24ClN3O4S	425.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCCCCCN=C(N)N	Ki > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BU79WT	N-[(1S)-5-Amino-1-cyanopentyl]-2-[(1R)-1-[3-(4-fluorophenyl)-2,5-dioxoimidazolidin-1-yl]ethyl]-3-methylbenzimidazole-5-carboxamide	Investigative	127046389	C26H28FN7O3	505.5	C[C@H](C1=NC2=C(N1C)C=C(C=C2)C(=O)N[C@@H](CCCCN)C#N)N3C(=O)CN(C3=O)C4=CC=C(C=C4)F	IC50 > 200000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BU7X8W	1H-Indole-5-carboximidamide, 1-ethyl-	Investigative	28742032	C11H13N3	187.24	CCN1C=CC2=C1C=CC(=C2)C(=N)N	Ki = 280000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BUHW20	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-[4-(2-amino-2-oxoethoxy)phenyl]-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655496	C26H29N9O5	547.6	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=C(C=C4)OCC(=O)N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BUK27D	1-(Pyrimidin-2-yl)guanidine	Investigative	12253733	C5H7N5	137.14	C1=CN=C(N=C1)N=C(N)N	Ki = 292000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BUO84D	Chembl4128554	Investigative	145960477	C21H25FN4O3S	432.5	C1CCC(CC1)[C@H](C(=O)NC2=CC=C(C=C2)C(=N)N)NS(=O)(=O)C3=CC=C(C=C3)F	IC50 = 280000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BV09MR	[[6-Amino-3-chloro-5-(diaminomethylidenecarbamoyl)pyrazin-2-yl]amino]methylphosphonic acid;hydrochloride	Investigative	57401489	C7H12Cl2N7O4P	360.09	C(NC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)P(=O)(O)O.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BV3U9R	N-[(1S)-5-Amino-1-cyanopentyl]-6-[[3-(3-cyanophenyl)-2,5-dioxoimidazolidin-1-yl]methyl]-7-methylpyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655494	C25H25N9O3	499.5	CN1C(=CC2=CN=C(N=C21)C(=O)N[C@@H](CCCCN)C#N)CN3C(=O)CN(C3=O)C4=CC=CC(=C4)C#N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BVLI64	N-[(1S)-5-Amino-1-cyanopentyl]-7-methyl-6-[(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl]pyrrolo[2,3-d]pyrimidine-2-carboxamide	Investigative	90655485	C19H24N8O3	412.4	CN1CC(=O)N(C1=O)CC2=CC3=CN=C(N=C3N2C)C(=O)N[C@@H](CCCCN)C#N	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BVW9Y6	2-[4-[[(2-Pyridin-3-ylimidazo[1,2-a]pyridin-3-yl)amino]methyl]phenyl]guanidine	Investigative	127040832	C20H19N7	357.4	C1=CC2=NC(=C(N2C=C1)NCC3=CC=C(C=C3)N=C(N)N)C4=CN=CC=C4	IC50 = 250000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BW26ZA	Amino(nicotinamido)methaniminium chloride	Investigative	57394526	C7H9ClN4O	200.62	C1=CC(=CN=C1)C(=O)N=C(N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BW2M6I	N-[2-(2,4-Dichlorophenoxy)ethyl]imidazo[1,2-a]pyridin-3-amine	Investigative	127040526	C15H13Cl2N3O	322.2	C1=CC2=NC=C(N2C=C1)NCCOC3=C(C=C(C=C3)Cl)Cl	IC50 = 250000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BWFB16	3-(4-Amidinophenyl)-2-[[[(4-cyanophenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	10695159	C21H23N5O5S	457.5	CCOC(=O)C(CC1=CC=C(C=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C#N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BX2VY0	(3R,8R,11S,14S,17S,20S,23S,26S,29S,32S)-3-Amino-29-(4-aminobutyl)-11,23-dibenzyl-20-[(1-carbamimidoylpiperidin-4-yl)methyl]-26-[3-(diaminomethylideneamino)propyl]-17-methyl-14-(2-methylpropyl)-2,10,13,16,19,22,25,28,31-nonaoxo-5,6-dithia-1,9,12,15,18,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontane-8-carboxylic acid	Investigative	127035672	C59H91N17O11S2	1278.6	C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CC3CCN(CC3)C(=N)N)CC4=CC=CC=C4)CCCN=C(N)N)CCCCN)N)C(=O)O)CC5=CC=CC=C5)CC(C)C	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BX9G8U	N-[1-(Piperidinocarbonyl)-2-[4-(diaminomethyl)phenyl]ethyl]-2-[(2-naphthylsulfonyl)amino]acetamide	Investigative	44367382	C27H33N5O4S	523.6	C1CCN(CC1)C(=O)C(CC2=CC=C(C=C2)C(N)N)NC(=O)CNS(=O)(=O)C3=CC4=CC=CC=C4C=C3	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BXC65D	3-(4-Amidinophenyl)-2-[[[(4-thiocarbamoylphenylsulfonyl)amino]acetyl]amino]propionic acid ethyl ester	Investigative	10767421	C21H25N5O5S2	491.6	CCOC(=O)C(CC1=CC=C(C=C1)C(=N)N)NC(=O)CNS(=O)(=O)C2=CC=C(C=C2)C(=S)N	Ki > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BY0CL5	3-[2-Amino-3-(4-methyl-piperidin-1-yl)-3-oxo-propyl]-benzamidine	Investigative	4713420	C16H24N4O	288.39	CC1CCN(CC1)C(=O)C(CC2=CC(=CC=C2)C(=N)N)N	Ki = 800000 nM	Non binder
T17758	Urokinase-type plasminogen activator	BZ49EA	5-Amino-6-bromo-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride	Investigative	57403238	C6H8BrClN6O	295.52	C1=C(N=C(C(=N1)N)Br)C(=O)N=C(N)N.Cl	IC50 > 1000000 nM	Non binder
T17758	Urokinase-type plasminogen activator	D08OCL	4-(5-Nitro-indol-1-ylmethyl)-benzamidine	Investigative	44331823	C16H14N4O2	294.31	C1=CC(=CC=C1CN2C=CC3=C2C=CC(=C3)[N+](=O)[O-])C(=N)N	Ki > 200000 nM	Non binder