TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T18664	Monoglyceride lipase	B06ADK	Phenyl 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60165945	C24H24N2S2	404.6	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=S)SC4=CC=CC=C4	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B0B3YR	3-[4-(2-Methylpropyl)phenyl]-1-nitrobutan-2-one	Investigative	46933424	C14H19NO3	249.3	CC(C)CC1=CC=C(C=C1)C(C)C(=O)C[N+](=O)[O-]	IC50 = 489778.82 nM	Non binder
T18664	Monoglyceride lipase	B0XMQ7	(4-(Dimethylamino)phenyl)(morpholino)methanethione	Investigative	691987	C13H18N2OS	250.36	CN(C)C1=CC=C(C=C1)C(=S)N2CCOCC2	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B13EUG	2-(3,4-Dimethoxy-phenyl)-1-morpholin-4-yl-ethanethione	Investigative	766352	C14H19NO3S	281.37	COC1=C(C=C(C=C1)CC(=S)N2CCOCC2)OC	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B15GZA	Methyl morpholine-4-carbodithioate	Investigative	5043631	C6H11NOS2	177.3	CSC(=S)N1CCOCC1	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B1FD3R	N-(2-Phenylethyl)-2-(4-phenylphenyl)ethanethioamide	Investigative	76330314	C22H21NS	331.5	C1=CC=C(C=C1)CCNC(=S)CC2=CC=C(C=C2)C3=CC=CC=C3	IC50 = 537031.8 nM	Non binder
T18664	Monoglyceride lipase	B1R6SK	Chembl4293042	Investigative	145986519	C29H42FNO3	471.6	CCCCCCCCCCCCCCC/C(=N\\O)/C1=C(C=CC(=C1)C2=CC(=C(C=C2)OC)F)O	IC50 > 200000 nM	Non binder
T18664	Monoglyceride lipase	B1WA8E	4-(4-Chlorobenzyl)morpholine	Investigative	783204	C11H14ClNO	211.69	C1COCCN1CC2=CC=C(C=C2)Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B2OBZ7	(4-Chlorophenyl) 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60165947	C24H23ClN2S2	439	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=S)SC4=CC=C(C=C4)Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B36DEQ	3,4-Dihydroxy-N-(2-phenylethyl)benzenecarbothioamide	Investigative	136245185	C15H15NO2S	273.4	C1=CC=C(C=C1)CCNC(=S)C2=CC(=C(C=C2)O)O	IC50 = 524807.46 nM	Non binder
T18664	Monoglyceride lipase	B37CGX	(3-Methylphenyl)-piperidin-1-ylmethanethione	Investigative	20111303	C13H17NS	219.35	CC1=CC(=CC=C1)C(=S)N2CCCCC2	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B3AMC4	Morpholine, 4-(thiobenzoyl)-	Investigative	16244	C11H13NOS	207.29	C1COCCN1C(=S)C2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B3Q9BP	1-(Phenylthioxomethyl)piperidine	Investigative	285275	C12H15NS	205.32	C1CCN(CC1)C(=S)C2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B3RWG9	N-(2-Phenylethyl)benzenecarbothioamide	Investigative	708576	C15H15NS	241.4	C1=CC=C(C=C1)CCNC(=S)C2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B41SJO	4-[(4-Phenylphenyl)methyl]morpholine	Investigative	782503	C17H19NO	253.34	C1COCCN1CC2=CC=C(C=C2)C3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B49CVN	1-[4-(4-Fluorophenyl)piperazin-1-yl]-2-[5-(4-methoxyphenyl)tetrazol-2-yl]ethanone	Investigative	1373946	C20H21FN6O2	396.4	COC1=CC=C(C=C1)C2=NN(N=N2)CC(=O)N3CCN(CC3)C4=CC=C(C=C4)F	IC50 > 500000 nM	Non binder
T18664	Monoglyceride lipase	B49EXL	(2,4-Dichlorophenyl)(morpholino)methanethione	Investigative	4737564	C11H11Cl2NOS	276.2	C1COCCN1C(=S)C2=C(C=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B4RMS0	(2-Chlorophenyl)(morpholin-4-yl)methanone	Investigative	225451	C11H12ClNO2	225.67	C1COCCN1C(=O)C2=CC=CC=C2Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B53SOM	2-[5-(4-Morpholin-4-ylphenyl)tetrazol-2-yl]-1-(4-phenylpiperazin-1-yl)ethanone	Investigative	1373945	C23H27N7O2	433.5	C1CN(CCN1C2=CC=CC=C2)C(=O)CN3N=C(N=N3)C4=CC=C(C=C4)N5CCOCC5	IC50 > 500000 nM	Non binder
T18664	Monoglyceride lipase	B5FE2J	(4-Tert-butylphenyl) 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60166100	C28H32N2S2	460.7	CC(C)(C)C1=CC=C(C=C1)SC(=S)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B63OQX	N-(1-Benzylpiperidin-4-yl)-5-(4-hydroxyphenyl)-1-phenylpyrazole-3-carboxamide	Investigative	137656145	C28H28N4O2	452.5	C1CN(CCC1NC(=O)C2=NN(C(=C2)C3=CC=C(C=C3)O)C4=CC=CC=C4)CC5=CC=CC=C5	IC50 > 200000 nM	Non binder
T18664	Monoglyceride lipase	B7I5MS	(4-Cyclohexylphenyl)-morpholin-4-ylmethanethione	Investigative	76323092	C17H23NOS	289.4	C1CCC(CC1)C2=CC=C(C=C2)C(=S)N3CCOCC3	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B7RG8H	1-Phenyl-5-(4-phenylmethoxyphenyl)-N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]pyrazole-3-carboxamide	Investigative	137653784	C33H33N7O2	559.7	C1CN(CCN1CCNC(=O)C2=NN(C(=C2)C3=CC=C(C=C3)OCC4=CC=CC=C4)C5=CC=CC=C5)C6=NC=CC=N6	IC50 > 200000 nM	Non binder
T18664	Monoglyceride lipase	B7S2RO	1-[4-[4-(4-Fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl]-2-phenylethanone	Investigative	1075551	C24H28FN3O2	409.5	C1CN(CCC1C(=O)N2CCN(CC2)C3=CC=C(C=C3)F)C(=O)CC4=CC=CC=C4	IC50 > 500000 nM	Non binder
T18664	Monoglyceride lipase	B8H1PE	Ibuproxam, dimethyl deriv.	Investigative	46933421	C15H23NO2	249.35	CC(C)CC1=CC=C(C=C1)C(C)C(=O)N(C)OC	IC50 = 645654.23 nM	Non binder
T18664	Monoglyceride lipase	B8VX2H	Morpholin-4-yl-(4-phenylphenyl)methanone	Investigative	2189777	C17H17NO2	267.32	C1COCCN1C(=O)C2=CC=C(C=C2)C3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	B9JP5V	2-[[5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl]-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone	Investigative	1171867	C22H24N4O4S	440.5	COC1=CC=C(C=C1)C2=NN=C(O2)SCC(=O)N3CCN(CC3)C4=CC=C(C=C4)OC	IC50 > 500000 nM	Non binder
T18664	Monoglyceride lipase	B9QY1J	(Diethylcarbamoyl)methylene diethylcarbamodithioate	Investigative	13258570	C11H22N2OS2	262.4	CCN(CC)C(=O)CSC(=S)N(CC)CC	IC50 = 630957.34 nM	Non binder
T18664	Monoglyceride lipase	B9VQ2M	(2-Chlorophenyl) 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60166095	C24H23ClN2S2	439	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=S)SC4=CC=CC=C4Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BBA05M	(4-Acetylphenyl) 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60166098	C26H26N2OS2	446.6	CC(=O)C1=CC=C(C=C1)SC(=S)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BBR4K9	2,3-Bis(furan-3-yl)-N-[(4-methoxyphenyl)methyl]quinoxaline-6-carboxamide	Investigative	6502047	C25H19N3O4	425.4	COC1=CC=C(C=C1)CNC(=O)C2=CC3=C(C=C2)N=C(C(=N3)C4=COC=C4)C5=COC=C5	IC50 > 500000 nM	Non binder
T18664	Monoglyceride lipase	BD17GV	2-(4-Benzhydrylpiperazin-1-yl)-1-phenyl-2-sulfanylideneethanone	Investigative	60165943	C25H24N2OS	400.5	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=S)C(=O)C4=CC=CC=C4	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BDS3R6	Chembl4293107	Investigative	145988983	C27H38FNO3	443.6	CCCCCCCCCCCCC/C(=N\\O)/C1=C(C=CC(=C1)C2=CC(=C(C=C2)OC)F)O	IC50 > 200000 nM	Non binder
T18664	Monoglyceride lipase	BFW35E	[4-(Trifluoromethyl)phenyl] 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60166227	C25H23F3N2S2	472.6	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=S)SC4=CC=C(C=C4)C(F)(F)F	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BG5B1N	(3,4-Dichlorophenyl)(morpholino)methanethione	Investigative	895402	C11H11Cl2NOS	276.2	C1COCCN1C(=S)C2=CC(=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BG9Z5R	5-(4-Nitro-benzoyl)-2-pyridin-3-yl-isoindole-1,3-dione	Investigative	1130422	C20H11N3O5	373.3	C1=CC(=CN=C1)N2C(=O)C3=C(C2=O)C=C(C=C3)C(=O)C4=CC=C(C=C4)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T18664	Monoglyceride lipase	BGS97E	[1-Phenyl-5-(4-phenylmethoxyphenyl)pyrazol-3-yl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone	Investigative	137640733	C31H28N6O2	516.6	C1CN(CCN1C2=NC=CC=N2)C(=O)C3=NN(C(=C3)C4=CC=C(C=C4)OCC5=CC=CC=C5)C6=CC=CC=C6	IC50 > 200000 nM	Non binder
T18664	Monoglyceride lipase	BJLF17	Methyl diethyldithiocarbamate	Investigative	12704	C6H13NS2	163.3	CCN(CC)C(=S)SC	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BK9C1S	4-Chloro-N-(2-phenylethyl)benzenecarbothioamide	Investigative	11536404	C15H14ClNS	275.8	C1=CC=C(C=C1)CCNC(=S)C2=CC=C(C=C2)Cl	IC50 = 436515.83 nM	Non binder
T18664	Monoglyceride lipase	BLW39S	2-Morpholino-2-oxoethyl morpholine-4-carbodithioate	Investigative	44550865	C11H18N2O3S2	290.4	C1COCCN1C(=O)CSC(=S)N2CCOCC2	IC50 = 218776.16 nM	Non binder
T18664	Monoglyceride lipase	BN1DR0	Morpholine, 4-(phenylthioacetyl)-	Investigative	70362	C12H15NOS	221.32	C1COCCN1C(=S)CC2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BOA73N	N-(4-Acetylphenyl)-1-(4-ethoxyphenyl)-5-oxopyrrolidine-3-carboxamide	Investigative	3155531	C21H22N2O4	366.4	CCOC1=CC=C(C=C1)N2CC(CC2=O)C(=O)NC3=CC=C(C=C3)C(=O)C	IC50 > 500000 nM	Non binder
T18664	Monoglyceride lipase	BP2JA6	(3-Chlorophenyl)(morpholino)methanethione	Investigative	12639462	C11H12ClNOS	241.74	C1COCCN1C(=S)C2=CC(=CC=C2)Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BQD04L	1-Pent-4-enoyl-3-(pent-4-enyl)azetidin-2-one	Investigative	24894033	C13H19NO2	221.29	C=CCCCC1CN(C1=O)C(=O)CCC=C	IC50 = 657000 nM	Non binder
T18664	Monoglyceride lipase	BSY0T7	N-(4-Chlorobenzoyl)morpholine	Investigative	225452	C11H12ClNO2	225.67	C1COCCN1C(=O)C2=CC=C(C=C2)Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BT19FZ	(4-(Diphenylmethyl)piperazinyl)(phenylamino)methane-1-thione	Investigative	1109251	C24H25N3S	387.5	C1CN(CCN1C(C2=CC=CC=C2)C3=CC=CC=C3)C(=S)NC4=CC=CC=C4	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BU9Z3R	(4-Methoxyphenyl) 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60166097	C25H26N2OS2	434.6	COC1=CC=C(C=C1)SC(=S)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BV5GE7	2-Octyl-1,2-benzoxazol-3-one	Investigative	57398502	C15H21NO2	247.33	CCCCCCCCN1C(=O)C2=CC=CC=C2O1	IC50 = 275000 nM	Non binder
T18664	Monoglyceride lipase	BV95BA	4-Fluoro-N-(2-phenylethyl)benzenecarbothioamide	Investigative	20110740	C15H14FNS	259.3	C1=CC=C(C=C1)CCNC(=S)C2=CC=C(C=C2)F	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BVUO23	4-(2-Chlorobenzyl)morpholine	Investigative	782978	C11H14ClNO	211.69	C1COCCN1CC2=CC=CC=C2Cl	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BZ9I8R	(4-Hydroxyphenyl)(morpholino)methanethione	Investigative	289457	C11H13NO2S	223.29	C1COCCN1C(=S)C2=CC=C(C=C2)O	IC50 = 204173.79 nM	Non binder
T18664	Monoglyceride lipase	BZCU51	(4-Methylphenyl) 4-benzhydrylpiperazine-1-carbodithioate	Investigative	60165946	C25H26N2S2	418.6	CC1=CC=C(C=C1)SC(=S)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4	IC50 > 1000000 nM	Non binder
T18664	Monoglyceride lipase	BZU76D	5-(4-Hydroxyphenyl)-1-phenyl-N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]pyrazole-3-carboxamide	Investigative	137657257	C26H27N7O2	469.5	C1CN(CCN1CCNC(=O)C2=NN(C(=C2)C3=CC=C(C=C3)O)C4=CC=CC=C4)C5=NC=CC=N5	IC50 > 200000 nM	Non binder
T18664	Monoglyceride lipase	D06BGU	(+/-)-3-(but-3-enyl)-1-pent-4-enoylazetidin-2-one	Investigative	44560666	C12H17NO2	207.27	C=CCCC1CN(C1=O)C(=O)CCC=C	IC50 = 817000 nM	Non binder