TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T19160	Group IIA phospholipase A2	D09JUG	Zileuton	Approved	60490	C11H12N2O2S	236.29	CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O	IC50 > 1000000 nM	Non binder
T19160	Group IIA phospholipase A2	B0OR7V	4-[4-[2,4-Dihydroxy-3,6-dimethyl-5-[(1-phenylethylamino)methyl]benzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoic acid	Investigative	76331562	C38H41NO10	671.7	CC1=C(C(=C(C(=C1C(=O)O)O)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=C(C(=C(C(=C3C)CNC(C)C4=CC=CC=C4)O)C)O)C)O)C	IC50 = 1800000 nM	Non binder
T19160	Group IIA phospholipase A2	B0V1FY	2-[[(2R)-2-[[2-[[5-(2-Benzamido-4-methyl-1,3-thiazol-5-yl)-1H-pyrazole-3-carbonyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetic acid	Investigative	71716414	C25H30N10O6S	598.6	CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2)C3=CC(=NN3)C(=O)NCC(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)O	IC50 = 217000 nM	Non binder
T19160	Group IIA phospholipase A2	B1AZ7W	4-[4-[2,4-Dihydroxy-3,6-dimethyl-5-[[[(1S)-1-phenylethyl]amino]methyl]benzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoic acid	Investigative	122197355	C38H41NO10	671.7	CC1=C(C(=C(C(=C1C(=O)O)O)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=C(C(=C(C(=C3C)CN[C@@H](C)C4=CC=CC=C4)O)C)O)C)O)C	IC50 = 840000 nM	Non binder
T19160	Group IIA phospholipase A2	B2Q5DL	Bis[3-[[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenoxy]carbonyl]-4-methoxyphenyl] sulfoxide	Investigative	10843834	C60H62O19S	1119.2	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=C(C=CC(=C3)S(=O)C4=CC(=C(C=C4)OC)C(=O)OC5=C(C(=C(C(=C5C)C)C(=O)OC6=C(C(=C(C(=C6C)C)C(=O)O)OC)C)OC)C)OC)C)OC)C	IC50 = 260000 nM	Non binder
T19160	Group IIA phospholipase A2	B43FIH	4-[4-[5-[[5-[4-(4-Carboxy-3-hydroxy-2,5,6-trimethylphenoxy)carbonyl-3-hydroxy-2,5,6-trimethylphenoxy]carbonyl-2,4-dihydroxy-3,6-dimethylphenyl]methyl]-2,4-dihydroxy-3,6-dimethylbenzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoyl]oxy-2-hydroxy-3,5,6-trimethylbenzoic acid	Investigative	16144962	C59H60O20	1089.1	CC1=C(C(=C(C(=C1C(=O)O)O)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=C(C(=C(C(=C3C)CC4=C(C(=C(C(=C4O)C)O)C(=O)OC5=C(C(=C(C(=C5C)C)C(=O)OC6=C(C(=C(C(=C6C)C)C(=O)O)O)C)O)C)C)O)C)O)C)O)C	IC50 = 2400000 nM	Non binder
T19160	Group IIA phospholipase A2	B62ARO	4-[5-[[5-(4-Carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl-2,4-dimethoxy-3,6-dimethylphenyl]methyl]-2,4-dimethoxy-3,6-dimethylbenzoyl]oxy-2-methoxy-3,5,6-trimethylbenzoic acid	Investigative	10509638	C45H52O14	816.9	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)CC3=C(C(=C(C(=C3OC)C)OC)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)O)OC)C)C)OC)C)OC)C	IC50 = 2800000 nM	Non binder
T19160	Group IIA phospholipase A2	B6J3WN	(Z)-1-(4-Fluorophenyl)-3-[cyclohexyl(hydroxy)amino]-2-propen-1-one	Investigative	9992927	C15H18FNO2	263.31	C1CCC(CC1)N(/C=C\\C(=O)C2=CC=C(C=C2)F)O	IC50 > 1000000 nM	Non binder
T19160	Group IIA phospholipase A2	B8O1RA	Bis[3-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)-carbonyl]-4-methoxyphenyl]ether	Investigative	10723410	C38H38O13	702.7	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C=CC(=C2)OC3=CC(=C(C=C3)OC)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)O)OC)C)OC)C	IC50 = 75000000 nM	Non binder
T19160	Group IIA phospholipase A2	B8OY7V	Bis[3-[[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)-carbonyl]-4-methoxyphenyl]sulfide	Investigative	10842569	C38H38O12S	718.8	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C=CC(=C2)SC3=CC(=C(C=C3)OC)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)O)OC)C)OC)C	IC50 = 4800000 nM	Non binder
T19160	Group IIA phospholipase A2	B94EXR	(Z)-1-(4-Fluorophenyl)-3-[benzyl(acetyloxy)amino]-2-propen-1-one	Investigative	10018456	C18H16FNO3	313.3	CC(=O)ON(CC1=CC=CC=C1)/C=C\\C(=O)C2=CC=C(C=C2)F	IC50 > 1000000 nM	Non binder
T19160	Group IIA phospholipase A2	BB6Q2A	Succinic acid bis[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenyl] ester	Investigative	44365927	C48H54O16	886.9	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)CCC(=O)OC3=C(C(=C(C(=C3C)C)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)O)OC)C)OC)C)C)OC)C	IC50 = 940000 nM	Non binder
T19160	Group IIA phospholipase A2	BBK08D	2-[[5-(2-Benzamido-4-methyl-1,3-thiazol-5-yl)-1H-pyrazole-3-carbonyl]amino]acetic acid	Investigative	71719460	C17H15N5O4S	385.4	CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2)C3=CC(=NN3)C(=O)NCC(=O)O	IC50 = 241000 nM	Non binder
T19160	Group IIA phospholipase A2	BD48KF	2-Methoxy-4-[2-methoxy-4-[2-methoxy-5-(4-methoxyphenyl)sulfanylbenzoyl]oxy-3,5,6-trimethylbenzoyl]oxy-3,5,6-trimethylbenzoic acid	Investigative	44365796	C37H38O10S	674.8	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=C(C=CC(=C3)SC4=CC=C(C=C4)OC)OC)C)OC)C	IC50 = 4100000 nM	Non binder
T19160	Group IIA phospholipase A2	BI8OP5	Isophthalic acid bis[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenyl] ester	Investigative	44365929	C52H54O16	935	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=CC(=CC=C3)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)OC5=C(C(=C(C(=C5C)C)C(=O)O)OC)C)OC)C)C)OC)C	IC50 = 230000 nM	Non binder
T19160	Group IIA phospholipase A2	BJ4IH8	4-[4-[6-[4-(4-Carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl-3-methoxy-2,5,6-trimethylphenoxy]carbonyl-4-oxopyran-2-carbonyl]oxy-2-methoxy-3,5,6-trimethylbenzoyl]oxy-2-methoxy-3,5,6-trimethylbenzoic acid	Investigative	44365928	C51H52O18	952.9	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=CC(=O)C=C(O3)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)OC5=C(C(=C(C(=C5C)C)C(=O)O)OC)C)OC)C)C)OC)C	IC50 = 5800000 nM	Non binder
T19160	Group IIA phospholipase A2	BJK6N0	(2R)-2-[[2-[[5-(2-Benzamido-4-methyl-1,3-thiazol-5-yl)-1H-pyrazole-3-carbonyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	71718857	C23H27N9O5S	541.6	CC1=C(SC(=N1)NC(=O)C2=CC=CC=C2)C3=CC(=NN3)C(=O)NCC(=O)N[C@H](CCCN=C(N)N)C(=O)O	IC50 = 262000 nM	Non binder
T19160	Group IIA phospholipase A2	BME94Y	Phosphoric acid (R)-2-acetylamino-9-hydroxy-nonyl ester methyl ester	Investigative	44322593	C12H26NO6P	311.31	CC(=O)N[C@H](CCCCCCCO)COP(=O)(O)OC	IC50 = 350000 nM	Non binder
T19160	Group IIA phospholipase A2	BNF6C7	Thielocin A1	Investigative	10865991	C54H60O18	997	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)C3=C([C@@](C4([C@](C3=O)(CC5=C(C(=C(C(=C5O4)C)OC)C(=O)OC6=C(C(=C(C(=C6C)C)C(=O)O)OC)C)C)C)O)(C)O)C)C)OC)C	IC50 = 12000000 nM	Non binder
T19160	Group IIA phospholipase A2	BR12WH	(Z)-1-(4-Fluorophenyl)-3-[benzyl(hydroxy)amino]-2-propen-1-one	Investigative	10061734	C16H14FNO2	271.29	C1=CC=C(C=C1)CN(/C=C\\C(=O)C2=CC=C(C=C2)F)O	IC50 > 1000000 nM	Non binder
T19160	Group IIA phospholipase A2	BSDN30	(Z)-1-(4-Fluorophenyl)-3-[benzyl(methoxy)amino]-2-propen-1-one	Investigative	10424056	C17H16FNO2	285.31	CON(CC1=CC=CC=C1)/C=C\\C(=O)C2=CC=C(C=C2)F	IC50 > 1000000 nM	Non binder
T19160	Group IIA phospholipase A2	BVJ81K	4-[4-[5-[(2,4-Dimethoxy-3,6-dimethylphenyl)methyl]-2,4-dimethoxy-3,6-dimethylbenzoyl]oxy-2-methoxy-3,5,6-trimethylbenzoyl]oxy-2-methoxy-3,5,6-trimethylbenzoic acid	Investigative	122197356	C44H52O12	772.9	CC1=CC(=C(C(=C1CC2=C(C(=C(C(=C2OC)C)OC)C(=O)OC3=C(C(=C(C(=C3C)C)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)O)OC)C)OC)C)C)OC)C)OC	IC50 = 3000000 nM	Non binder
T19160	Group IIA phospholipase A2	BWCB59	Fumaric acid bis[4-[(4-carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl]-3-methoxy-2,5,6-trimethylphenyl] ester	Investigative	44365795	C48H52O16	884.9	CC1=C(C(=C(C(=C1C(=O)O)OC)C)OC(=O)C2=C(C(=C(C(=C2C)C)OC(=O)/C=C/C(=O)OC3=C(C(=C(C(=C3C)C)C(=O)OC4=C(C(=C(C(=C4C)C)C(=O)O)OC)C)OC)C)C)OC)C	IC50 = 2200000 nM	Non binder
T19160	Group IIA phospholipase A2	BZ72GC	4-[4-[5-[3-[4-(4-Carboxy-3-methoxy-2,5,6-trimethylphenoxy)carbonyl-3-methoxy-2,5,6-trimethylphenoxy]carbonyl-4-methoxy-5-methylphenoxy]-2,4-dimethoxybenzoyl]oxy-2-methoxy-3,5,6-trimethylbenzoyl]oxy-2-methoxy-3,5,6-trimethylbenzoic acid	Investigative	16157140	C62H66O20	1131.2	CC1=CC(=CC(=C1OC)C(=O)OC2=C(C(=C(C(=C2C)C)C(=O)OC3=C(C(=C(C(=C3C)C)C(=O)O)OC)C)OC)C)OC4=C(C=C(C(=C4)C(=O)OC5=C(C(=C(C(=C5C)C)C(=O)OC6=C(C(=C(C(=C6C)C)C(=O)O)OC)C)OC)C)OC)OC	IC50 = 240000 nM	Non binder
T19160	Group IIA phospholipase A2	D0O2DQ	Mepacrine	Investigative	237	C23H30ClN3O	400	CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC	IC50 = 76000000 nM	Non binder
T19160	Group IIA phospholipase A2	D0P1LP	PHENIDONE	Investigative	7090	C9H10N2O	162.19	C1CN(NC1=O)C2=CC=CC=C2	IC50 > 1000000 nM	Non binder