TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T23499 Endothelin A receptor B0MSB1 4-(1,1,1,3,3,3-Hexafluoro-2-methoxypropan-2-yl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide Investigative 134139749 C27H23F6N5O7S 675.6 COC1=CC=CC=C1OC2=C(N=C(N=C2OCCO)C3=NC=CC=N3)NS(=O)(=O)C4=CC=C(C=C4)C(C(F)(F)F)(C(F)(F)F)OC IC50 = 693000 nM Non binder T23499 Endothelin A receptor BGR40K 4-[(2R,3R)-3-[(3,4-Dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-1,2-dimethoxybenzene Investigative 9953821 C24H34O6 418.5 COC[C@H](CC1=CC(=C(C=C1)OC)OC)[C@@H](CC2=CC(=C(C=C2)OC)OC)COC IC50 > 1000000 nM Non binder