TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T24587	O-6-methylguanine-DNA-alkyltransferase	B2H7XV	6-Hex-3-enyloxy-9H-purin-2-ylamine	Investigative	10489822	C11H15N5O	233.27	CC/C=C\\CCOC1=NC(=NC2=C1NC=N2)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	B3OV7N	6-Hexyloxy-9H-purin-2-ylamine	Investigative	10681258	C11H17N5O	235.29	CCCCCCOC1=NC(=NC2=C1NC=N2)N	IC50 = 554000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	B5Q1PC	2-(2-Amino-9H-purin-6-yloxy)-1-phenyl-ethanone	Investigative	10659580	C13H11N5O2	269.26	C1=CC=C(C=C1)C(=O)COC2=NC(=NC3=C2NC=N3)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	B6HMI7	6-(Cyclopentylmethoxy)-7H-purin-2-amine	Investigative	5329509	C11H15N5O	233.27	C1CCC(C1)COC2=NC(=NC3=C2NC=N3)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	B89FXL	6-Butoxy-7H-purin-2-amine	Investigative	95803	C9H13N5O	207.23	CCCCOC1=NC(=NC2=C1NC=N2)N	IC50 = 493000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	B91DUN	O6-Substituted Guanine Deriv. 36	Investigative	5329520	C13H13N5O	255.28	C1=CC=C(C=C1)CCOC2=NC(=NC3=C2NC=N3)N	IC50 = 548000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	B9OE8I	2-Amino-4-benzyloxy-6-[N-(4,4''-diaminobenzophenone)]-5-nitropyrimidine	Investigative	53326716	C24H20N6O4	456.5	C1=CC=C(C=C1)COC2=NC(=NC(=C2[N+](=O)[O-])NC3=CC=C(C=C3)C(=O)C4=CC=C(C=C4)N)N	IC50 > 600000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BC1H4T	O6-Substituted Guanine Deriv. 42	Investigative	5329526	C11H17N5O3	267.28	CCC(COC1=NC(=NC2=C1NC=N2)N)(OC)OC	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BF7RA4	6-Ethylguanine	Investigative	95805	C7H9N5O	179.18	CCOC1=NC(=NC2=C1NC=N2)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BI0E3T	2-Amino-4-benzyloxy-6-[N-(4-(4-aminophenoxy)anilino)]-5-nitropyrimidine	Investigative	53317587	C23H20N6O4	444.4	C1=CC=C(C=C1)COC2=NC(=NC(=C2[N+](=O)[O-])NC3=CC=C(C=C3)OC4=CC=C(C=C4)N)N	IC50 > 600000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BNP54T	O6-Substituted Guanine Deriv. 11	Investigative	5329499	C10H15N5O	221.26	CC(C)CCOC1=NC(=NC2=C1NC=N2)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BO3PH5	6-Cyclobutylmethoxy-9H-purin-2-ylamine	Investigative	10704094	C10H13N5O	219.24	C1CC(C1)COC2=NC(=NC3=C2NC=N3)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BQ6S8K	Purine, 2-amino-6-propoxy-	Investigative	95802	C8H11N5O	193.21	CCCOC1=NC(=NC2=C1NC=N2)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BS9UV0	O6-Substituted Guanine Deriv. 18	Investigative	5329505	C11H15N5O	233.27	CC(C)C(=C)COC1=NC(=NC2=C1NC=N2)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BSR43O	6-(2,2-Dimethoxy-2-phenyl-ethoxy)-9H-purin-2-ylamine	Investigative	10639059	C15H17N5O3	315.33	COC(COC1=NC(=NC2=C1NC=N2)N)(C3=CC=CC=C3)OC	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BSW76L	2-Amino-6-methoxypurine	Investigative	65275	C6H7N5O	165.15	COC1=NC(=NC2=C1NC=N2)N	IC50 = 248000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BU5C7P	6-Pentoxy-7H-purin-2-amine	Investigative	5329494	C10H15N5O	221.26	CCCCCOC1=NC(=NC2=C1NC=N2)N	IC50 = 1006000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BU9HB4	1-[(2-Amino-6,9-dihydro-1H-purin-6-YL)oxy]-3-methyl-2-butanol	Investigative	445940	C10H13N5O2	235.24	CC(C)C(=O)COC1=NC(=NC2=C1NC=N2)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BXDQ30	O6-Substituted Guanine Deriv. 41	Investigative	5329525	C12H19N5O3	281.31	CCOC(C)(COC1=NC(=NC2=C1NC=N2)N)OCC	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BZ5RA9	6-(2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-9H-purin-2-ylamine	Investigative	10635398	C11H15N5O3	265.27	CC1(OCC(O1)COC2=NC(=NC3=C2NC=N3)N)C	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	D01FJB	6-(Cyclohex-3-enylmethoxy)-9H-purin-2-ylamine	Investigative	5329512	C12H15N5O	245.28	C1CC(CC=C1)COC2=NC(=NC3=C2NC=N3)N	IC50 > 1000000 nM	Non binder
T24587	O-6-methylguanine-DNA-alkyltransferase	D0R1FT	6-O-Cyclohexylmethyl Guanine	Investigative	4564	C12H17N5O	247.3	C1CCC(CC1)COC2=NC(=NC3=C2NC=N3)N	IC50 > 1000000 nM	Non binder