TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T26623	Aldose reductase	D07HBX	Salicyclic acid	Approved	338	C7H6O3	138.12	C1=CC=C(C(=C1)C(=O)O)O	IC50 > 1000000 nM	Non binder
T26623	Aldose reductase	B1P5FQ	(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12S,13R,14S,17S)-3,12-Dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	118720624	C42H72O14	801	CC(=CCC[C@@](C)([C@H]1CC[C@]2([C@@H]1[C@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)O)C)O)C	IC50 > 200000 nM	Non binder
T26623	Aldose reductase	B3D6IE	Ginsenoside C-K	Investigative	9852086	C36H62O8	622.9	CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C	IC50 > 200000 nM	Non binder
T26623	Aldose reductase	B5NY8P	(6-Hydroxy-5-oxo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-2-yl)-acetic acid	Investigative	13676782	C17H14O4	282.29	C1CC2=C(C=CC(=C2)CC(=O)O)C(=O)C3=C1C=CC=C3O	IC50 = 280000 nM	Non binder
T26623	Aldose reductase	B7TV9E	Ginsenoside Rh1	Investigative	12855920	C36H62O9	638.9	CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(C[C@@H]([C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)O)C)O)C	IC50 > 200000 nM	Non binder
T26623	Aldose reductase	B9UNS5	Vitexin	Investigative	5280441	C21H20O10	432.4	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O	IC50 = 566660 nM	Non binder
T26623	Aldose reductase	BA46DF	20(R)-Ginsenoside Rh2	Investigative	54580480	C36H62O8	622.9	CC(=CCC[C@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)C)O)C)O)C	IC50 > 200000 nM	Non binder
T26623	Aldose reductase	BJ9FR0	(4-Hydroxy-6-methoxy-2-methyl-chroman-4-yl)-acetic acid	Investigative	15749969	C13H16O5	252.26	C[C@@H]1C[C@](C2=C(O1)C=CC(=C2)OC)(CC(=O)O)O	IC50 = 281000 nM	Non binder
T26623	Aldose reductase	BO4N9E	Schembl20904263	Investigative	118711690	C36H62O8	622.9	CC(=CCCC(C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C)C)O)C)O)C	IC50 > 200000 nM	Non binder
T26623	Aldose reductase	BOR9A1	(20R)-Ginsenoside Rg3	Investigative	46887680	C42H72O13	785	CC(=CCC[C@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O)C	IC50 > 200000 nM	Non binder
T26623	Aldose reductase	BV6S0C	4-Hydroxycoumarin	Investigative	54682930	C9H6O3	162.14	C1=CC=C2C(=C1)C(=CC(=O)O2)O	IC50 > 400000 nM	Non binder
T26623	Aldose reductase	D01BKS	ginsenoside Rg3	Investigative	9918693	C42H72O13	785	CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)C)C)O)C)O)C	IC50 > 200000 nM	Non binder
T26623	Aldose reductase	D03ZMQ	COUMARIN	Investigative	323	C9H6O2	146.14	C1=CC=C2C(=C1)C=CC(=O)O2	IC50 > 500000 nM	Non binder
T26623	Aldose reductase	D0U8IF	[(125)I] RB129	Investigative	10114	C30H46O4	470.7	C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)C(=O)O	IC50 = 280000 nM	Non binder