TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T31946 Vascular endothelial growth factor receptor B3O2HA 2-Methyl-5-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-phenol Investigative 10131256 C14H14N4O 254.29 CC1=C(C=C(C=C1)NC2=NC=NN3C2=CC(=C3)C)O IC50 = 213000 nM Non binder T31946 Vascular endothelial growth factor receptor B46AES 5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-2-methyl-phenol Investigative 10199254 C15H16N4O 268.31 CC1=C(C=C(C=C1)NC2=NC=NN3C2=C(C(=C3)C)C)O IC50 = 310000 nM Non binder T31946 Vascular endothelial growth factor receptor B6YX1I (3-Chloro-4-fluoro-phenyl)-(7-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-yl)-amine Investigative 11288910 C13H10ClFN4 276.69 CC1=CC=C2N1N=CN=C2NC3=CC(=C(C=C3)F)Cl IC50 > 2500000 nM Non binder T31946 Vascular endothelial growth factor receptor B6Z8DR (3-Chloro-4-fluoro-phenyl)-(5-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-yl)-amine Investigative 11357877 C13H10ClFN4 276.69 CC1=C2C(=NC=NN2C=C1)NC3=CC(=C(C=C3)F)Cl IC50 > 2500000 nM Non binder T31946 Vascular endothelial growth factor receptor BEH50D (3-Chloro-4-fluoro-phenyl)-pyrrolo[2,1-f][1,2,4]triazin-4-yl-amine Investigative 11817879 C12H8ClFN4 262.67 C1=CN2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl IC50 > 2500000 nM Non binder T31946 Vascular endothelial growth factor receptor BG7TO1 2-Methyl-5-(pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-phenol Investigative 9794758 C13H12N4O 240.26 CC1=C(C=C(C=C1)NC2=NC=NN3C2=CC=C3)O IC50 = 360000 nM Non binder T31946 Vascular endothelial growth factor receptor BH48BA 2-Methyl-5-(7-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-phenol Investigative 10198953 C14H14N4O 254.29 CC1=C(C=C(C=C1)NC2=NC=NN3C2=CC=C3C)O IC50 = 477000 nM Non binder T31946 Vascular endothelial growth factor receptor BMN8I1 (3-Chloro-4-fluoro-phenyl)-(6-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-yl)-amine Investigative 11380375 C13H10ClFN4 276.69 CC1=CN2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl IC50 > 2500000 nM Non binder