TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T34562 Serum paraoxonase/arylesterase 1 B3C8DQ 1-(1H-Benzimidazol-1-ylmethyl)-1H-1,2,3-benzotriazole Investigative 639433 C14H11N5 249.27 C1=CC=C2C(=C1)N=CN2CN3C4=CC=CC=C4N=N3 IC50 = 564130 nM Non binder T34562 Serum paraoxonase/arylesterase 1 B7Q4TU Phosphoric acid, p-aminophenyl diethyl ester Investigative 197934 C10H16NO4P 245.21 CCOP(=O)(OCC)OC1=CC=C(C=C1)N IC50 = 1280000 nM Non binder T34562 Serum paraoxonase/arylesterase 1 B8Y1DV Diethyl phenyl phosphate Investigative 17280 C10H15O4P 230.2 CCOP(=O)(OCC)OC1=CC=CC=C1 IC50 = 3270000 nM Non binder T34562 Serum paraoxonase/arylesterase 1 BBFJ15 4-[[3-(Benzotriazol-1-ylmethyl)benzimidazol-3-ium-1-yl]methyl]-6-tert-butylchromen-2-one;chloride Investigative 127028661 C28H26ClN5O2 500 CC(C)(C)C1=CC2=C(C=C1)OC(=O)C=C2CN3C=[N+](C4=CC=CC=C43)CN5C6=CC=CC=C6N=N5.[Cl-] IC50 = 627000 nM Non binder T34562 Serum paraoxonase/arylesterase 1 BG6X2Q 4-[(2,3-Dimethylimidazol-3-ium-1-yl)methyl]-5,7-dimethylchromen-2-one;chloride Investigative 127028306 C17H19ClN2O2 318.8 CC1=CC(=C2C(=CC(=O)OC2=C1)CN3C=C[N+](=C3C)C)C.[Cl-] IC50 = 317310 nM Non binder T34562 Serum paraoxonase/arylesterase 1 BR3WH9 1-[(3-Butylbenzimidazol-1-ium-1-yl)methyl]benzotriazole;chloride Investigative 127028327 C18H20ClN5 341.8 CCCCN1C=[N+](C2=CC=CC=C21)CN3C4=CC=CC=C4N=N3.[Cl-] IC50 = 3333300 nM Non binder T34562 Serum paraoxonase/arylesterase 1 BRB0S6 2-[(2,3-Dimethylimidazol-3-ium-1-yl)methyl]-1H-benzimidazole;chloride Investigative 127027684 C13H15ClN4 262.74 CC1=[N+](C=CN1CC2=NC3=CC=CC=C3N2)C.[Cl-] IC50 = 625710 nM Non binder T34562 Serum paraoxonase/arylesterase 1 BU9KX7 1-[(3-Benzylbenzimidazol-1-ium-1-yl)methyl]benzotriazole;chloride Investigative 127028328 C21H18ClN5 375.9 C1=CC=C(C=C1)CN2C=[N+](C3=CC=CC=C32)CN4C5=CC=CC=C5N=N4.[Cl-] IC50 = 2064200 nM Non binder T34562 Serum paraoxonase/arylesterase 1 BUS27P 4-[[3-(Benzotriazol-1-ylmethyl)benzimidazol-3-ium-1-yl]methyl]-7,8-dimethylchromen-2-one;chloride Investigative 127028660 C26H22ClN5O2 471.9 CC1=C(C2=C(C=C1)C(=CC(=O)O2)CN3C=[N+](C4=CC=CC=C43)CN5C6=CC=CC=C6N=N5)C.[Cl-] IC50 = 237500 nM Non binder T34562 Serum paraoxonase/arylesterase 1 D0S9LT Phenylphosphate Investigative 12793 C6H7O4P 174.09 C1=CC=C(C=C1)OP(=O)(O)O IC50 = 3250000 nM Non binder T34562 Serum paraoxonase/arylesterase 1 D0T0YI 4-nitrophenyl phosphate Investigative 378 C6H6NO6P 219.09 C1=CC(=CC=C1[N+](=O)[O-])OP(=O)(O)O IC50 = 18500000 nM Non binder