TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T34867 Poly [ADP-ribose] polymerase 1 B3JM9T Nicotinamide Investigative 936 C6H6N2O 122.12 C1=CC(=CN=C1)C(=O)N IC50 = 210000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 B4R8AN 4-Chlorobenzamide Investigative 12084 C7H6ClNO 155.58 C1=CC(=CC=C1C(=O)N)Cl IC50 = 300000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 B5TPQ2 4-Bromobenzamide Investigative 69683 C7H6BrNO 200.03 C1=CC(=CC=C1C(=O)N)Br IC50 = 2200000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 B6Z9RY 3,5-Dichloro-N-(2-chlorophenyl)-2-hydroxybenzamide Investigative 53391638 C13H8Cl3NO2 316.6 C1=CC=C(C(=C1)NC(=O)C2=C(C(=CC(=C2)Cl)Cl)O)Cl IC50 = 500000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 BC1AG3 3,5-Dichloro-N-(3-chlorophenyl)-2-hydroxybenzamide Investigative 3014425 C13H8Cl3NO2 316.6 C1=CC(=CC(=C1)Cl)NC(=O)C2=C(C(=CC(=C2)Cl)Cl)O IC50 = 500000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 BF4XE8 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-Dihydroxypyrrolidin-2-YL]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]adenosine Investigative 6918639 C15H24N6O12P2 542.33 C1[C@@H]([C@@H]([C@H](N1)COP(=O)(O)OP(=O)(O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O)O)O IC50 > 1000000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 BIMP28 4-Hydroxybenzamide Investigative 65052 C7H7NO2 137.14 C1=CC(=CC=C1C(=O)N)O IC50 = 280000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 BO0CV1 4-Aminobenzamide Investigative 76079 C7H8N2O 136.15 C1=CC(=CC=C1C(=O)N)N IC50 = 1800000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 BQX72S CID 66716715 Investigative 66716715 C23H28N4O4 424.5 CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=CC=C(C=C4)C(=O)NC)OC EC50 = 251000 nM Non binder T34867 Poly [ADP-ribose] polymerase 1 BU2S9T 6-[2-Fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]-2,6-diazatricyclo[7.3.1.05,13]trideca-1(12),9(13),10-trien-3-one Investigative 71604718 C27H21FN4O3 468.5 C1CN(C2CC(=O)NC3=CC=CC1=C23)C(=O)C4=C(C=CC(=C4)CC5=NNC(=O)C6=CC=CC=C65)F IC50 = 387000 nM Non binder