TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T35527 Arachidonate 12-lipoxygenase B1T5UJ 5-[(2-Methoxybenzyl)oxy]-7-methyl-4-phenyl-2H-chromen-2-one Investigative 1325172 C24H20O4 372.4 CC1=CC2=C(C(=CC(=O)O2)C3=CC=CC=C3)C(=C1)OCC4=CC=CC=C4OC IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase B5A7CD N''-[(2-Chloro-4-methylbenzoyl)oxy]-3-methylbenzenecarboximidamide Investigative 9586795 C16H15ClN2O2 302.75 CC1=CC(=CC=C1)/C(=N/OC(=O)C2=C(C=C(C=C2)C)Cl)/N IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase B6PL0Q Pyridine-2,6-dicarboxylic acid bis-(phenethyl-amide) Investigative 1095055 C23H23N3O2 373.4 C1=CC=C(C=C1)CCNC(=O)C2=NC(=CC=C2)C(=O)NCCC3=CC=CC=C3 IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase B8QR0C Halenaquinol sulfate Investigative 23425708 C20H13NaO8S 436.4 C[C@@]12CCC(=O)C3=COC(=C31)C(=O)C4=CC5=C(C=CC(=C5C=C24)OS(=O)(=O)[O-])O.[Na+] IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase BD4Y7H 2-(4-Chloro-2-methylphenoxy)-N-[2-hydroxy-5-(propan-2-yl)phenyl]acetamide Investigative 801015 C18H20ClNO3 333.8 CC1=C(C=CC(=C1)Cl)OCC(=O)NC2=C(C=CC(=C2)C(C)C)O IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase BH64KM 2-(3-Chlorophenoxy)-N-(4-methylbenzyl)propanamide Investigative 2933060 C17H18ClNO2 303.8 CC1=CC=C(C=C1)CNC(=O)C(C)OC2=CC(=CC=C2)Cl IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase BI74UH 2-Phenoxy-N-{[4-(pyridin-4-ylmethyl)phenyl]carbamothioyl}acetamide Investigative 1346428 C21H19N3O2S 377.5 C1=CC=C(C=C1)OCC(=O)NC(=S)NC2=CC=C(C=C2)CC3=CC=NC=C3 IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase BNV89J N-(5-Butyramido-2-chlorophenyl)benzofuran-2-carboxamide Investigative 1082938 C19H17ClN2O3 356.8 CCCC(=O)NC1=CC(=C(C=C1)Cl)NC(=O)C2=CC3=CC=CC=C3O2 IC50 > 200000 nM Non binder T35527 Arachidonate 12-lipoxygenase BR5V8K N-Benzyl-3-((2,3-dihydro-1H-inden-5-yloxy)methyl)benzamide Investigative 2192753 C24H23NO2 357.4 C1CC2=C(C1)C=C(C=C2)OCC3=CC(=CC=C3)C(=O)NCC4=CC=CC=C4 IC50 > 500000 nM Non binder T35527 Arachidonate 12-lipoxygenase BV8HP1 2-Chloro-N-{2-methyl-4-[(phenylsulfanyl)methyl]phenyl}benzamide Investigative 1743704 C21H18ClNOS 367.9 CC1=C(C=CC(=C1)CSC2=CC=CC=C2)NC(=O)C3=CC=CC=C3Cl IC50 > 200000 nM Non binder