TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T36483	Proteinase activated receptor 1	B13YOA	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10415062	C27H46N8O4	546.7	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	B24QUH	(2S)-N-[(2R)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10439062	C30H51N9O6	633.8	CC(C)C[C@@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)N	EC50 = 500000 nM	Non binder
T36483	Proteinase activated receptor 1	B2DLF3	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10416585	C31H53N9O5	631.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C(C)(C)N	EC50 = 415000 nM	Non binder
T36483	Proteinase activated receptor 1	B2WQL9	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-(2,3,4,5,6-pentafluorophenyl)propanoyl]amino]-4-methylpentanamide	Investigative	9987318	C30H46F5N9O5	707.7	C[C@@H](C(=O)N[C@@H](CC1=C(C(=C(C(=C1F)F)F)F)F)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 = 600000 nM	Non binder
T36483	Proteinase activated receptor 1	B4MTH5	Fllrdpqdk-NH2	Investigative	10260648	C50H82N16O13	1115.3	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CC2=CC=CC=C2)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	B57NTU	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2R)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	11764645	C30H51N9O6	633.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	B75LQG	(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	90663353	C41H50ClFN8O6	805.3	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)Cl)NC(=O)[C@H](CC2=CC=C(C=C2)F)N(C(=O)C)C(=O)/C=C/C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T36483	Proteinase activated receptor 1	B8RT6P	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]-methylamino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10394462	C31H53N9O6	647.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)N(C)C(=O)[C@H](CO)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	B8XVO6	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10078455	C33H58N12O5	702.9	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCN=C(N)N)N	EC50 > 1200000 nM	Non binder
T36483	Proteinase activated receptor 1	BAS53D	(2S)-2-[[(2R)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-4-phenylbutanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	90663336	C42H53FN8O6	784.9	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@@H](CCC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)F)N(C(=O)C)C(=O)/C=C/C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T36483	Proteinase activated receptor 1	BC54VY	(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(4-methoxyphenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	90663309	C42H53FN8O7	800.9	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OC)NC(=O)[C@H](CC2=CC=C(C=C2)F)N(C(=O)C)C(=O)/C=C/C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T36483	Proteinase activated receptor 1	BC9R0B	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-4-phenylbutanoyl]amino]-4-methylpentanamide	Investigative	10439025	C31H53N9O5	631.8	C[C@@H](C(=O)N[C@@H](CCC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BF50BR	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-phenylpropanoyl]amino]-N,4-dimethylpentanamide	Investigative	44354460	C31H53N9O5	631.8	C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 = 260000 nM	Non binder
T36483	Proteinase activated receptor 1	BG81TS	(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	90663351	C41H50FN9O8	815.9	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)[C@H](CC2=CC=C(C=C2)F)N(C(=O)C)C(=O)/C=C/C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T36483	Proteinase activated receptor 1	BIE9W8	(2S)-N-[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-2-phenylacetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanamide	Investigative	44354062	C29H49N9O5	603.8	C[C@@H](C(=O)N[C@@H](C1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BJ07NU	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2R)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10416607	C30H51N9O6	633.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](CO)N	EC50 = 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BKR17Z	(S)-3-Amino-N-((S)-1-{(S)-1-[(S)-1-((S)-1-carbamoyl-4-guanidino-butylcarbamoyl)-3-methyl-butylcarbamoyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethyl)-succinamic acid	Investigative	10484500	C31H51N9O7	661.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(=O)O)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BMU94N	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]propanoyl]amino]-4-methylpentanamide	Investigative	10099272	C24H47N9O6	557.7	C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CO)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BODN86	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-4-methylpentanamide	Investigative	9986700	C31H54N10O5	646.8	C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)CN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 = 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BS1PE6	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-3-(4-aminophenyl)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-4-methylpentanamide	Investigative	10416597	C30H52N10O5	632.8	C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 = 235000 nM	Non binder
T36483	Proteinase activated receptor 1	BT39FP	(2S)-N-[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]-methylamino]-4-methylpentanoyl]amino]-4-methylpentanamide	Investigative	10416780	C31H53N9O6	647.8	CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)N	EC50 = 350000 nM	Non binder
T36483	Proteinase activated receptor 1	BTZ94R	(2S)-2-[[(2S)-2-(4-Aminobutanoylamino)-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide	Investigative	10054787	C31H53N9O5	631.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CCCN	EC50 = 730000 nM	Non binder
T36483	Proteinase activated receptor 1	BV0NH6	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-methylamino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	44354052	C31H53N9O5	631.8	C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N(C)[C@@H](CCCN=C(N)N)C(=O)N)N	EC50 = 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BV3Z2R	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methyl-2-[[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]-3-phenylpropanoyl]amino]pentanamide	Investigative	44354387	C31H53N9O5	631.8	C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC	EC50 = 600000 nM	Non binder
T36483	Proteinase activated receptor 1	BX9FD5	(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10462502	C36H55N9O6	709.9	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N	EC50 = 400000 nM	Non binder
T36483	Proteinase activated receptor 1	BXAT90	L-Phenylalaninamide, L-seryl-	Investigative	7006478	C12H17N3O3	251.28	C1=CC=C(C=C1)C[C@@H](C(=O)N)NC(=O)[C@H](CO)N	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BY7OT1	Ac-SFLLRDPQDK-NH2	Investigative	10441247	C49H77N15O15	1116.2	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)C	EC50 > 800000 nM	Non binder
T36483	Proteinase activated receptor 1	BZ2X3O	(2R)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide	Investigative	10416608	C30H51N9O6	633.8	CC(C)C[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)N	EC50 > 800000 nM	Non binder