TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T36729	NADPH oxidase 2	B0RQ4K	(5-Hydroxy-1H-indol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	71116233	C20H21N3O3	351.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)O	IC50 = 500000000 nM	Non binder
T36729	NADPH oxidase 2	B1FNU6	(6-Methoxy-1H-benzimidazol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	71116642	C20H22N4O3	366.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=NC4=C(N3)C=C(C=C4)OC	IC50 = 1000000000 nM	Non binder
T36729	NADPH oxidase 2	B2ELW1	2-(4-Acetylanilino)-1-[4-(4-methoxyphenyl)-3-methylpiperazin-1-yl]ethanone	Investigative	71116205	C22H27N3O3	381.5	CC1CN(CCN1C2=CC=C(C=C2)OC)C(=O)CNC3=CC=C(C=C3)C(=O)C	IC50 = 600000000 nM	Non binder
T36729	NADPH oxidase 2	B2HSF6	(6-Fluoro-1H-benzimidazol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	71116322	C19H19FN4O2	354.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=NC4=C(N3)C=C(C=C4)F	IC50 = 700000000 nM	Non binder
T36729	NADPH oxidase 2	B2TYS0	(5-Fluoro-3-methyl-1H-indol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	71116186	C21H22FN3O2	367.4	CC1=C(NC2=C1C=C(C=C2)F)C(=O)N3CCN(CC3)C4=CC=C(C=C4)OC	IC50 = 700000000 nM	Non binder
T36729	NADPH oxidase 2	B3Q9IH	[4-(4-Ethoxyphenyl)piperazin-1-yl]-(6-fluoro-1H-benzimidazol-2-yl)methanone	Investigative	71116554	C20H21FN4O2	368.4	CCOC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=NC4=C(N3)C=C(C=C4)F	IC50 = 800000000 nM	Non binder
T36729	NADPH oxidase 2	B3U7YV	2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-1H-indole-5-carboxamide	Investigative	71473870	C21H22N4O3	378.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)C(=O)N	IC50 = 700000000 nM	Non binder
T36729	NADPH oxidase 2	B4BJP0	1-[2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-3-methyl-1H-indol-5-yl]ethanone	Investigative	71116724	C23H25N3O3	391.5	CC1=C(NC2=C1C=C(C=C2)C(=O)C)C(=O)N3CCN(CC3)C4=CC=C(C=C4)OC	IC50 = 1000000000 nM	Non binder
T36729	NADPH oxidase 2	B4XHE1	6-Fluoro-3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1H-quinolin-4-one	Investigative	71116219	C21H20FN3O3	381.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CNC4=C(C3=O)C=C(C=C4)F	IC50 = 1500000000 nM	Non binder
T36729	NADPH oxidase 2	B51GRB	1-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-(4-propan-2-ylanilino)ethanone	Investigative	71116531	C22H29N3O2	367.5	CC(C)C1=CC=C(C=C1)NCC(=O)N2CCN(CC2)C3=CC=C(C=C3)OC	IC50 = 800000000 nM	Non binder
T36729	NADPH oxidase 2	B53YMH	2-[(3-Fluorophenyl)amino]-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one	Investigative	17467640	C19H22FN3O2	343.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)CNC3=CC(=CC=C3)F	IC50 = 1000000000 nM	Non binder
T36729	NADPH oxidase 2	B5K1IQ	2-(3,4-Difluoroanilino)-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone	Investigative	71116271	C19H21F2N3O2	361.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)CNC3=CC(=C(C=C3)F)F	IC50 = 600000000 nM	Non binder
T36729	NADPH oxidase 2	B5L8KG	(5-Methoxy-1H-indol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	71116535	C21H23N3O3	365.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)OC	IC50 = 500000000 nM	Non binder
T36729	NADPH oxidase 2	B5ODY9	2-(4-Acetylanilino)-1-[4-(2-aminophenyl)piperazin-1-yl]ethanone	Investigative	24178261	C20H24N4O2	352.4	CC(=O)C1=CC=C(C=C1)NCC(=O)N2CCN(CC2)C3=CC=CC=C3N	IC50 = 4000000000 nM	Non binder
T36729	NADPH oxidase 2	B5R2FN	1H-Indol-2-yl-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	9271969	C20H21N3O2	335.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=CC=CC=C4N3	IC50 = 500000000 nM	Non binder
T36729	NADPH oxidase 2	B5S8QK	(5,6-Dimethoxy-1H-indol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	71116244	C22H25N3O4	395.5	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=CC(=C(C=C4N3)OC)OC	IC50 = 800000000 nM	Non binder
T36729	NADPH oxidase 2	B63VSG	1-[2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-1H-indol-5-yl]ethanone	Investigative	71116385	C22H23N3O3	377.4	CC(=O)C1=CC2=C(C=C1)NC(=C2)C(=O)N3CCN(CC3)C4=CC=C(C=C4)OC	IC50 = 400000000 nM	Non binder
T36729	NADPH oxidase 2	B7LJF0	2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-1H-indole-5-carboxylic acid	Investigative	71473922	C21H21N3O4	379.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)C(=O)O	IC50 = 500000000 nM	Non binder
T36729	NADPH oxidase 2	B7O3MZ	1-[2-[4-(4-Ethoxyphenyl)piperazine-1-carbonyl]-1H-indol-5-yl]ethanone	Investigative	71473923	C23H25N3O3	391.5	CCOC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)C(=O)C	IC50 = 800000000 nM	Non binder
T36729	NADPH oxidase 2	B80OJF	2-(4-Acetylanilino)-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone	Investigative	18096451	C21H25N3O3	367.4	CC(=O)C1=CC=C(C=C1)NCC(=O)N2CCN(CC2)C3=CC=C(C=C3)OC	IC50 = 400000000 nM	Non binder
T36729	NADPH oxidase 2	B8XI7G	1-[2-[4-(3-Fluoro-4-methoxyphenyl)piperazine-1-carbonyl]-1H-indol-5-yl]ethanone	Investigative	71116283	C22H22FN3O3	395.4	CC(=O)C1=CC2=C(C=C1)NC(=C2)C(=O)N3CCN(CC3)C4=CC(=C(C=C4)OC)F	IC50 = 3000000000 nM	Non binder
T36729	NADPH oxidase 2	BA9JD3	2-(4-Fluoroanilino)-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone	Investigative	51178287	C19H22FN3O2	343.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)CNC3=CC=C(C=C3)F	IC50 = 3000000000 nM	Non binder
T36729	NADPH oxidase 2	BADW87	2-[4-(4-Propan-2-yloxyphenyl)piperazine-1-carbonyl]-3H-benzimidazole-5-carboxamide	Investigative	90276063	C22H25N5O3	407.5	CC(C)OC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=NC4=C(N3)C=C(C=C4)C(=O)N	IC50 = 1000000000 nM	Non binder
T36729	NADPH oxidase 2	BC5PM1	2-[4-(3-Fluoro-4-methoxyphenyl)piperazine-1-carbonyl]-N-methyl-1H-indole-5-carboxamide	Investigative	90276087	C22H23FN4O3	410.4	CNC(=O)C1=CC2=C(C=C1)NC(=C2)C(=O)N3CCN(CC3)C4=CC(=C(C=C4)OC)F	IC50 = 10000000000 nM	Non binder
T36729	NADPH oxidase 2	BCH0X9	(5-Hydroxy-1H-indol-2-yl)-[4-[4-(trifluoromethoxy)phenyl]piperazin-1-yl]methanone	Investigative	123685165	C20H18F3N3O3	405.4	C1CN(CCN1C2=CC=C(C=C2)OC(F)(F)F)C(=O)C3=CC4=C(N3)C=CC(=C4)O	IC50 = 1500000000 nM	Non binder
T36729	NADPH oxidase 2	BE9TO7	2-(4-Acetylanilino)-1-[4-(3,4-dimethoxyphenyl)piperazin-1-yl]ethanone	Investigative	71116273	C22H27N3O4	397.5	CC(=O)C1=CC=C(C=C1)NCC(=O)N2CCN(CC2)C3=CC(=C(C=C3)OC)OC	IC50 = 1300000000 nM	Non binder
T36729	NADPH oxidase 2	BK1Q4Z	2-[4-(4-Methoxyphenyl)piperazine-1-carbonyl]-N-methyl-1H-indole-5-carboxamide	Investigative	71116278	C22H24N4O3	392.5	CNC(=O)C1=CC2=C(C=C1)NC(=C2)C(=O)N3CCN(CC3)C4=CC=C(C=C4)OC	IC50 = 500000000 nM	Non binder
T36729	NADPH oxidase 2	BKMS06	2-(4-Acetylanilino)-1-[4-(2-hydroxyphenyl)piperazin-1-yl]ethanone	Investigative	24178263	C20H23N3O3	353.4	CC(=O)C1=CC=C(C=C1)NCC(=O)N2CCN(CC2)C3=CC=CC=C3O	IC50 = 500000000 nM	Non binder
T36729	NADPH oxidase 2	BL4T6F	7-Acetyl-3-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1H-quinolin-4-one	Investigative	71116153	C23H23N3O4	405.4	CC(=O)C1=CC2=C(C=C1)C(=O)C(=CN2)C(=O)N3CCN(CC3)C4=CC=C(C=C4)OC	IC50 = 1000000000 nM	Non binder
T36729	NADPH oxidase 2	BNQ78I	1-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-(N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]-4-propan-2-ylanilino)ethanone	Investigative	90274779	C35H45N5O4	599.8	CC(C)C1=CC=C(C=C1)N(CC(=O)N2CCN(CC2)C3=CC=C(C=C3)OC)CC(=O)N4CCN(CC4)C5=CC=C(C=C5)OC	IC50 = 1000000000 nM	Non binder
T36729	NADPH oxidase 2	BOUQ32	2-[4-(3-Fluoro-4-methoxyphenyl)piperazine-1-carbonyl]-1H-indole-5-carboxamide	Investigative	90275921	C21H21FN4O3	396.4	COC1=C(C=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)C(=O)N)F	IC50 = 2000000000 nM	Non binder
T36729	NADPH oxidase 2	BQ1P3D	2-(4-Acetylanilino)-1-[4-(4-hydroxyphenyl)piperazin-1-yl]ethanone	Investigative	71116154	C20H23N3O3	353.4	CC(=O)C1=CC=C(C=C1)NCC(=O)N2CCN(CC2)C3=CC=C(C=C3)O	IC50 = 100000000 nM	Non binder
T36729	NADPH oxidase 2	BQ3FM0	1-[2-[4-(4-Propan-2-yloxyphenyl)piperazine-1-carbonyl]-1H-indol-5-yl]ethanone	Investigative	71473924	C24H27N3O3	405.5	CC(C)OC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)C(=O)C	IC50 = 1000000000 nM	Non binder
T36729	NADPH oxidase 2	BS37LN	2-[(2-Fluorophenyl)amino]-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethan-1-one	Investigative	17472090	C19H22FN3O2	343.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)CNC3=CC=CC=C3F	IC50 = 4500000000 nM	Non binder
T36729	NADPH oxidase 2	BSU2Q4	2-(4-Acetylanilino)-1-[4-(4-aminophenyl)piperazin-1-yl]ethanone	Investigative	90276060	C20H24N4O2	352.4	CC(=O)C1=CC=C(C=C1)NCC(=O)N2CCN(CC2)C3=CC=C(C=C3)N	IC50 = 200000000 nM	Non binder
T36729	NADPH oxidase 2	BUB67J	Methyl 2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-1H-indole-5-carboxylate	Investigative	71473869	C22H23N3O4	393.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)C(=O)OC	IC50 = 300000000 nM	Non binder
T36729	NADPH oxidase 2	BXS41R	(5-Fluoro-1H-indol-2-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone	Investigative	4911524	C20H20FN3O2	353.4	COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)F	IC50 = 5000000000 nM	Non binder
T36729	NADPH oxidase 2	BY28HX	2-(4-Acetylanilino)-1-[4-(4-ethoxyphenyl)piperazin-1-yl]ethanone	Investigative	71116201	C22H27N3O3	381.5	CCOC1=CC=C(C=C1)N2CCN(CC2)C(=O)CNC3=CC=C(C=C3)C(=O)C	IC50 = 500000000 nM	Non binder
T36729	NADPH oxidase 2	BYS26T	Methyl 1-(5-fluoro-1H-indole-2-carbonyl)-4-(4-methoxyphenyl)piperazine-2-carboxylate	Investigative	129626256	C22H22FN3O4	411.4	COC1=CC=C(C=C1)N2CCN(C(C2)C(=O)OC)C(=O)C3=CC4=C(N3)C=CC(=C4)F	IC50 = 1000000000 nM	Non binder