TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T40474	Proto-oncogene c-Met	B24AVP	[4-Amino-2-[[4-[4-(1-methylethyl)-1-piperazinyl]phenyl]amino]-5-thiazolyl](3-methoxyphenyl)methanone	Investigative	9933545	C24H29N5O2S	451.6	CC(C)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC(=C(S3)C(=O)C4=CC(=CC=C4)OC)N	IC50 > 20000000 nM	Non binder
T40474	Proto-oncogene c-Met	B3CA2Q	1-N'-[3-Fluoro-4-[(2-oxo-1,3-dihydroimidazo[4,5-b]pyridin-7-yl)oxy]phenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide	Investigative	118724403	C23H17F2N5O4	465.4	C1CC1(C(=O)NC2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C(=NC=C4)NC(=O)N5)F	IC50 = 209000 nM	Non binder
T40474	Proto-oncogene c-Met	B72YPM	1'-Methyl-6-[9-(quinolin-6-ylmethyl)purin-2-yl]spiro[1H-indole-3,4'-piperidine]-2-one	Investigative	57398126	C28H25N7O	475.5	CN1CCC2(CC1)C3=C(C=C(C=C3)C4=NC=C5C(=N4)N(C=N5)CC6=CC7=C(C=C6)N=CC=C7)NC2=O	IC50 = 1400000 nM	Non binder
T40474	Proto-oncogene c-Met	B7NT6H	1'-Methyl-6-[3-(quinolin-6-ylmethyl)triazolo[4,5-d]pyrimidin-5-yl]spiro[1H-indole-3,4'-piperidine]-2-one	Investigative	57391060	C27H24N8O	476.5	CN1CCC2(CC1)C3=C(C=C(C=C3)C4=NC=C5C(=N4)N(N=N5)CC6=CC7=C(C=C6)N=CC=C7)NC2=O	IC50 = 1200000 nM	Non binder
T40474	Proto-oncogene c-Met	BJK82D	1'-Methyl-5-[9-(quinolin-6-ylmethyl)purin-2-yl]spiro[1H-indole-3,4'-piperidine]-2-one	Investigative	57401549	C28H25N7O	475.5	CN1CCC2(CC1)C3=C(C=CC(=C3)C4=NC=C5C(=N4)N(C=N5)CC6=CC7=C(C=C6)N=CC=C7)NC2=O	IC50 = 1100000 nM	Non binder
T40474	Proto-oncogene c-Met	BTB6A5	1-N-(4-Fluorophenyl)-1-N'-[3-fluoro-4-(1,3,8-triazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraen-6-yloxy)phenyl]cyclopropane-1,1-dicarboxamide	Investigative	118724405	C27H23F2N5O3	503.5	C1CCN2C(=NC3=C(C=CN=C32)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F)C1	IC50 = 260000 nM	Non binder
T40474	Proto-oncogene c-Met	D09RYV	Ro-0505124	Investigative	9911652	C23H25N5O3S	451.5	CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC(=C(S3)C(=O)C4=CC5=C(C=C4)OCCO5)N	IC50 > 20000000 nM	Non binder