TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T40556	Bromodomain-containing protein 4	D08HVE	Dimethyl Sulfoxide	Approved	679	C2H6OS	78.14	CS(=O)C	IC50 = 280000000 nM	Non binder
T40556	Bromodomain-containing protein 4	B01VHO	Chembl4291774	Investigative	75375570	C17H24N4O2S	348.5	CC1CC(CN(C1)CC2=CSC(=N2)NC(=O)C3=C(N=C(O3)C)C)C	IC50 > 200000 nM	Non binder
T40556	Bromodomain-containing protein 4	B2HM8O	(2S)-2-(Hydroxymethyl)-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one	Investigative	69236418	C10H12N2O2	192.21	C1[C@H](NC2=CC=CC=C2NC1=O)CO	IC50 > 200000 nM	Non binder
T40556	Bromodomain-containing protein 4	B30YQB	(4s)-4-Methyl-1,3,4,5-tetrahydro-2h-1,5-benzodiazepin-2-one	Investigative	735746	C10H12N2O	176.21	C[C@H]1CC(=O)NC2=CC=CC=C2N1	IC50 = 3700000 nM	Non binder
T40556	Bromodomain-containing protein 4	B73BZR	(R)-(-)-JQ1 Enantiomer	Investigative	49871818	C23H25ClN4O2S	457	CC1=C(SC2=C1C(=N[C@@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C	IC50 = 8354000 nM	Non binder
T40556	Bromodomain-containing protein 4	B74AOB	3-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one	Investigative	3152392	C10H12N2O	176.21	CC1CNC2=CC=CC=C2NC1=O	IC50 > 200000 nM	Non binder
T40556	Bromodomain-containing protein 4	B7WKQ5	3-Methyl-8-(2-dimethylaminoethylamino)pyrido[3,4-b]pyridine-2(1H)-one	Investigative	122180536	C13H18N4O	246.31	CC1=CC2=C(C(=NC=C2)NCCN(C)C)NC1=O	IC50 > 501187.23 nM	Non binder
T40556	Bromodomain-containing protein 4	B9V3YB	1,3,4,5-Tetrahydro-2H-1,5-benzodiazepin-2-one	Investigative	223771	C9H10N2O	162.19	C1CNC2=CC=CC=C2NC1=O	IC50 > 200000 nM	Non binder
T40556	Bromodomain-containing protein 4	BKSJ63	Chembl4228106	Investigative	145969777	C14H15NO3	245.27	CCCN1C=C(C2=CC=CC=C2C1=O)C(=O)OC	IC50 > 200000 nM	Non binder
T40556	Bromodomain-containing protein 4	BL73OJ	(2R)-2-Ethyl-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one	Investigative	121277645	C11H14N2O	190.24	CC[C@@H]1CC(=O)NC2=CC=CC=C2N1	IC50 > 200000 nM	Non binder
T40556	Bromodomain-containing protein 4	BQ38KS	4-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one	Investigative	19868	C10H12N2O	176.21	CC1CC(=O)NC2=CC=CC=C2N1	IC50 = 220000 nM	Non binder
T40556	Bromodomain-containing protein 4	BRZX96	4,4-Dimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one	Investigative	12206142	C11H14N2O	190.24	CC1(CC(=O)NC2=CC=CC=C2N1)C	IC50 > 200000 nM	Non binder
T40556	Bromodomain-containing protein 4	BY05SW	(2S)-6-Acetamido-N-methyl-2-(methylamino)hexanamide	Investigative	76318560	C10H21N3O2	215.29	CC(=O)NCCCC[C@@H](C(=O)NC)NC	IC50 = 7000000 nM	Non binder
T40556	Bromodomain-containing protein 4	BYVF35	1-Methyl-2-pyrrolidinone	Investigative	13387	C5H9NO	99.13	CN1CCCC1=O	IC50 = 6000000 nM	Non binder
T40556	Bromodomain-containing protein 4	BZV96X	(4r)-4-Methyl-1,3,4,5-tetrahydro-2h-1,5-benzodiazepin-2-one	Investigative	735747	C10H12N2O	176.21	C[C@@H]1CC(=O)NC2=CC=CC=C2N1	IC50 = 260000 nM	Non binder