TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T48069	Insulin-like growth factor I receptor	D0RT2C	AZD9291	Phase 3	71496458	C28H33N7O2	499.6	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC	IC50 = 2900000 nM	Non binder
T48069	Insulin-like growth factor I receptor	B0BUI3	Chembl4213021	Investigative	145966502	C18H14BrN3O	368.2	C1=CC(=CC(=C1)Br)CNC2=C3C4=C(C=CC(=C4)N)OC3=NC=C2	IC50 > 1000000 nM	Non binder
T48069	Insulin-like growth factor I receptor	B24AVP	[4-Amino-2-[[4-[4-(1-methylethyl)-1-piperazinyl]phenyl]amino]-5-thiazolyl](3-methoxyphenyl)methanone	Investigative	9933545	C24H29N5O2S	451.6	CC(C)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC(=C(S3)C(=O)C4=CC(=CC=C4)OC)N	IC50 = 20000000 nM	Non binder
T48069	Insulin-like growth factor I receptor	B5IWZ8	N-(Pyridin-3-ylmethyl)benzofuro[2,3-b]pyridin-4-amine	Investigative	52942862	C17H13N3O	275.3	C1=CC=C2C(=C1)C3=C(C=CN=C3O2)NCC4=CN=CC=C4	Ki > 1000000 nM	Non binder
T48069	Insulin-like growth factor I receptor	B8B6AY	Chembl4209296	Investigative	145966828	C18H14ClN3O	323.8	C1=CC(=CC=C1CNC2=C3C4=C(C=CC(=C4)N)OC3=NC=C2)Cl	IC50 > 1000000 nM	Non binder
T48069	Insulin-like growth factor I receptor	B8JV3D	1421373-98-9	Investigative	71496460	C27H31N7O2	485.6	CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CNC4=CC=CC=C43)OC	IC50 = 263000 nM	Non binder
T48069	Insulin-like growth factor I receptor	BC2W1E	Indirubin	Investigative	10177	C16H10N2O2	262.26	C1=CC=C2C(=C1)C(=C(N2)O)C3=NC4=CC=CC=C4C3=O	IC50 > 1000000 nM	Non binder
T48069	Insulin-like growth factor I receptor	BC97IN	Chembl4216200	Investigative	145973277	C19H17N3O2	319.4	COC1=CC=C(C=C1)CNC2=C3C4=C(C=CC(=C4)N)OC3=NC=C2	IC50 > 1000000 nM	Non binder
T48069	Insulin-like growth factor I receptor	BOS24Y	Chembl4202409	Investigative	145975494	C18H14BrN3O	368.2	C1=CC(=CC=C1CNC2=C3C4=C(C=CC(=C4)N)OC3=NC=C2)Br	IC50 > 1000000 nM	Non binder
T48069	Insulin-like growth factor I receptor	D09RYV	Ro-0505124	Investigative	9911652	C23H25N5O3S	451.5	CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC(=C(S3)C(=O)C4=CC5=C(C=C4)OCCO5)N	IC50 = 22000000 nM	Non binder