TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T48330 Large neutral amino acids transporter 1 B10RCW (R)-2-Amino-3-cyclohexylpropanoic acid Investigative 736026 C9H17NO2 171.24 C1CCC(CC1)C[C@H](C(=O)O)N IC50 = 260000 nM Non binder T48330 Large neutral amino acids transporter 1 B1L7YA (R)-2-Amino-2-methyl-3-phenylpropanoic acid Investigative 7023409 C10H13NO2 179.22 C[C@@](CC1=CC=CC=C1)(C(=O)O)N IC50 = 810000 nM Non binder T48330 Large neutral amino acids transporter 1 B3RTM0 Chembl4248655 Investigative 145983610 C11H13NO4 223.22 CC1=CC(=CC(=C1)C(=O)O)C[C@@H](C(=O)O)N IC50 = 680000 nM Non binder T48330 Large neutral amino acids transporter 1 B5OBT1 alpha-Benzyl-D-methionine Investigative 12085165 C12H17NO2S 239.34 CSCC[C@](CC1=CC=CC=C1)(C(=O)O)N IC50 = 240000 nM Non binder T48330 Large neutral amino acids transporter 1 B71SVP 4-(Methoxycarbonyl)-L-phenylalanine Investigative 45116514 C11H13NO4 223.22 COC(=O)C1=CC=C(C=C1)C[C@@H](C(=O)O)N IC50 = 260000 nM Non binder T48330 Large neutral amino acids transporter 1 B73ZKW D-Leucine Investigative 439524 C6H13NO2 131.17 CC(C)C[C@H](C(=O)O)N IC50 = 220000 nM Non binder T48330 Large neutral amino acids transporter 1 BJHX08 D-Valine Investigative 71563 C5H11NO2 117.15 CC(C)[C@H](C(=O)O)N IC50 > 50000000 nM Non binder T48330 Large neutral amino acids transporter 1 BP8C1H D-Tyrosine Investigative 71098 C9H11NO3 181.19 C1=CC(=CC=C1C[C@H](C(=O)O)N)O IC50 = 380000 nM Non binder T48330 Large neutral amino acids transporter 1 BWN8D1 (S)-2-Amino-3-(3-(aminomethyl)phenyl)propanoic acid Investigative 2762277 C10H14N2O2 194.23 C1=CC(=CC(=C1)CN)C[C@@H](C(=O)O)N IC50 = 470000 nM Non binder T48330 Large neutral amino acids transporter 1 BWUM91 D-Alloisoleucine Investigative 94206 C6H13NO2 131.17 CC[C@H](C)[C@H](C(=O)O)N IC50 > 3000000 nM Non binder T48330 Large neutral amino acids transporter 1 D08CBB D-tryptophan Investigative 9060 C11H12N2O2 204.22 C1=CC=C2C(=C1)C(=CN2)C[C@H](C(=O)O)N IC50 = 380000 nM Non binder T48330 Large neutral amino acids transporter 1 D0PG8L D-histidine Investigative 71083 C6H9N3O2 155.15 C1=C(NC=N1)C[C@H](C(=O)O)N IC50 = 460000 nM Non binder