TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T53389	TGF-beta receptor type I	B1Z6FE	4-(2-Aminophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one	Investigative	16730986	C19H17N5O	331.4	CN1C(=C(C(=O)N1C)C2=CC=CC=C2N)C3=CC4=NC=CN=C4C=C3	Ki = 952000 nM	Non binder
T53389	TGF-beta receptor type I	B2ZVU9	4-(4-Hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one	Investigative	135772000	C19H16N4O2	332.4	CN1C(=C(C(=O)N1C)C2=CC=C(C=C2)O)C3=CC4=NC=CN=C4C=C3	Ki = 950000 nM	Non binder
T53389	TGF-beta receptor type I	B8UT6Y	4-(3-Isopropylphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one	Investigative	16731073	C22H22N4O	358.4	CC(C)C1=CC=CC(=C1)C2=C(N(N(C2=O)C)C)C3=CC4=NC=CN=C4C=C3	Ki > 2800000 nM	Non binder
T53389	TGF-beta receptor type I	BE75WJ	4-(3-(Aminomethyl)phenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one	Investigative	16730907	C20H19N5O	345.4	CN1C(=C(C(=O)N1C)C2=CC=CC(=C2)CN)C3=CC4=NC=CN=C4C=C3	Ki > 2800000 nM	Non binder
T53389	TGF-beta receptor type I	BG3R0B	N-(3-(1,2-Dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihydro-1H-pyrazol-4-yl)phenyl)ethanesulfonamide	Investigative	46226928	C21H21N5O3S	423.5	CCS(=O)(=O)NC1=CC=CC(=C1)C2=C(N(N(C2=O)C)C)C3=CC4=NC=CN=C4C=C3	Ki > 2800000 nM	Non binder
T53389	TGF-beta receptor type I	BRV78X	3-(1,2-Dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihydro-1H-pyrazol-4-yl)benzamide	Investigative	16730418	C20H17N5O2	359.4	CN1C(=C(C(=O)N1C)C2=CC(=CC=C2)C(=O)N)C3=CC4=NC=CN=C4C=C3	Ki > 2800000 nM	Non binder
T53389	TGF-beta receptor type I	BS2BK0	2-(1,2-Dimethyl-3-oxo-5-quinoxalin-6-yl-2,3-dihydro-1H-pyrazol-4-yl)-benzonitrile	Investigative	16730257	C20H15N5O	341.4	CN1C(=C(C(=O)N1C)C2=CC=CC=C2C#N)C3=CC4=NC=CN=C4C=C3	Ki = 450000 nM	Non binder
T53389	TGF-beta receptor type I	BTE7L6	4-(4-Aminophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one	Investigative	16730417	C19H17N5O	331.4	CN1C(=C(C(=O)N1C)C2=CC=C(C=C2)N)C3=CC4=NC=CN=C4C=C3	Ki = 640000 nM	Non binder
T53389	TGF-beta receptor type I	BW6VY8	1-(3-(1,2-Dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihydro-1H-pyrazol-4-yl)phenyl)-3-methylurea	Investigative	46226924	C21H20N6O2	388.4	CNC(=O)NC1=CC=CC(=C1)C2=C(N(N(C2=O)C)C)C3=CC4=NC=CN=C4C=C3	Ki > 2800000 nM	Non binder