TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T53585	HMG-CoA reductase	B09BHU	L-Leucyl-L-prolyl-L-tyrosyl-L-proline	Investigative	44451976	C25H36N4O6	488.6	CC(C)C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N3CCC[C@H]3C(=O)O)N	IC50 = 484720 nM	Non binder
T53585	HMG-CoA reductase	B20JWH	alpha,beta-Dehydrmonacolin S	Investigative	132521485	C24H36O6	420.5	CC[C@H](C)C(=O)O[C@H]1C[C@H]([C@@H](C2=C[C@H]([C@@H]([C@@H]([C@@H]12)CC[C@@H]3CC=CC(=O)O3)C)O)O)C	IC50 = 387000 nM	Non binder
T53585	HMG-CoA reductase	BBK30J	7-[(1S,2S,6S)-6-(2,2-Dimethylpropanoyloxymethyl)-2-methylcyclohex-3-en-1-yl]-3,5-dihydroxyheptanoic acid	Investigative	44365204	C20H34O6	370.5	C[C@H]1C=CC[C@@H]([C@H]1CCC(CC(CC(=O)O)O)O)COC(=O)C(C)(C)C	IC50 = 1500000 nM	Non binder
T53585	HMG-CoA reductase	BL75FU	(4R,6S)-6-((E)-2-(2-Cyclopropyl-6,7-difluoro-4-(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one	Investigative	46227476	C28H27F2NO3S	495.6	CC(C)C1=CC=C(C=C1)SC2=C(C(=NC3=CC(=C(C=C32)F)F)C4CC4)/C=C/[C@@H]5C[C@H](CC(=O)O5)O	IC50 = 759000 nM	Non binder
T53585	HMG-CoA reductase	BT7K5S	(4R,6S)-6-((E)-2-(2-Cyclopropyl-6,7-difluoro-4-(3-methoxyphenylthio)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one	Investigative	46227475	C26H23F2NO4S	483.5	COC1=CC(=CC=C1)SC2=C(C(=NC3=CC(=C(C=C32)F)F)C4CC4)/C=C/[C@@H]5C[C@H](CC(=O)O5)O	IC50 = 359600 nM	Non binder
T53585	HMG-CoA reductase	BZ39MH	Iavpgeva	Investigative	44451948	C34H58N8O11	754.9	CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)O)N	IC50 = 201120 nM	Non binder