TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T54156	Matrix metalloproteinase-9	D00HNB	Clodronate	Approved	25419	CH4Cl2O6P2	244.89	C(P(=O)(O)O)(P(=O)(O)O)(Cl)Cl	IC50 = 320000 nM	Non binder
T54156	Matrix metalloproteinase-9	B0XE9S	((4S,5S)-2-Heptyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol	Investigative	44394727	C13H23NO2	225.33	CCCCCCCC1=N[C@H]([C@@H](O1)C=C)CO	Ki > 2000000 nM	Non binder
T54156	Matrix metalloproteinase-9	B37BEO	(S)-N-Hydroxy-2,5-bis(4-iodophenylsulfonamido)pentanamide	Investigative	44576877	C17H19I2N3O6S2	679.3	C1=CC(=CC=C1S(=O)(=O)NCCC[C@@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)I)I	Ki = 221000 nM	Non binder
T54156	Matrix metalloproteinase-9	B4I0GO	((4S,5S)-2-Pentyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol	Investigative	44394721	C11H19NO2	197.27	CCCCCC1=N[C@H]([C@@H](O1)C=C)CO	Ki > 2000000 nM	Non binder
T54156	Matrix metalloproteinase-9	B4P2DM	(2R)-1-[(2-Chlorophenyl)methyl]-N-hydroxy-5-oxopyrrolidine-2-carboxamide	Investigative	57393177	C12H13ClN2O3	268.69	C1CC(=O)N([C@H]1C(=O)NO)CC2=CC=CC=C2Cl	IC50 > 500000 nM	Non binder
T54156	Matrix metalloproteinase-9	B4QEH7	(2R)-2-[(3R)-3-Amino-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]-2-oxopyrrolidin-1-yl]-N-hydroxy-3-methylbutanamide	Investigative	53320639	C26H30N4O4	462.5	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)[C@@]4(CCN(C4=O)[C@H](C(C)C)C(=O)NO)N	IC50 = 460000 nM	Non binder
T54156	Matrix metalloproteinase-9	B5AXL3	(2R)-1-[(4-Chlorophenyl)methyl]-N-hydroxy-5-oxopyrrolidine-2-carboxamide	Investigative	57393178	C12H13ClN2O3	268.69	C1CC(=O)N([C@H]1C(=O)NO)CC2=CC=C(C=C2)Cl	IC50 = 430000 nM	Non binder
T54156	Matrix metalloproteinase-9	B68HAL	2-(Benzyl-hydroxycarbamoylmethyl-amino)-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide	Investigative	25178356	C19H24N4O5S	420.5	C1=CC=C(C=C1)CN(CC(=O)NCCC2=CC=C(C=C2)S(=O)(=O)N)CC(=O)NO	IC50 > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	B6WV8B	(S)-N-Hydroxy-2,5-bis(4-(trifluoromethyl)phenylsulfonamido)pentanamide	Investigative	44576851	C19H19F6N3O6S2	563.5	C1=CC(=CC=C1C(F)(F)F)S(=O)(=O)NCCC[C@@H](C(=O)NO)NS(=O)(=O)C2=CC=C(C=C2)C(F)(F)F	Ki = 329000 nM	Non binder
T54156	Matrix metalloproteinase-9	B7FWD5	L-Leucyl-L-phenylalanine methylamide	Investigative	18394511	C16H25N3O2	291.39	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)N	IC50 > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	B8R9AG	D-Leucyl-L-phenylalanine methylamide	Investigative	15296844	C16H25N3O2	291.39	CC(C)C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)N	IC50 > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	BB98UI	3,2-Diguanidinoneamine	Investigative	23645953	C14H30N8O6	406.44	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N=C(N)N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N=C(N)N)O)O)N	Ki > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	BBJ17R	(S)-2-Benzenesulfonylamino-N-hydroxy-3-phenyl-propionamide	Investigative	44372668	C15H16N2O4S	320.4	C1=CC=C(C=C1)C[C@@H](C(=O)NO)NS(=O)(=O)C2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T54156	Matrix metalloproteinase-9	BGV24B	Neamine guanidinylated deriv. 29	Investigative	23645959	C20H42N12O6	546.6	CO[C@H]1[C@@H](C[C@@H]([C@H]([C@@H]1OC)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN=C(N)N)OC)OC)N=C(N)N)N=C(N)N)N=C(N)N	Ki > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	BIFP05	2-Amino-5-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenol	Investigative	54757202	C15H15NO4S2	337.4	C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC(=C(C=C3)N)O	Ki = 490000 nM	Non binder
T54156	Matrix metalloproteinase-9	BK2ZL3	Neamine guanidinylated deriv. 4	Investigative	9957228	C16H34N12O6	490.5	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N=C(N)N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN=C(N)N)O)O)N=C(N)N)O)O)N=C(N)N	Ki > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	BMDV75	((4S,5S)-2-Phenyl-5-vinyl-4,5-dihydro-oxazol-4-yl)-methanol	Investigative	44394814	C12H13NO2	203.24	C=C[C@H]1[C@@H](N=C(O1)C2=CC=CC=C2)CO	Ki > 4000000 nM	Non binder
T54156	Matrix metalloproteinase-9	BMY37I	Chembl4202548	Investigative	145976989	C22H20O4S2	412.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)SC3=CC=CC=C3C(=O)CS(=O)(=O)C	IC50 = 332000 nM	Non binder
T54156	Matrix metalloproteinase-9	BR7N6M	N-Hydroxy-2,3-bis(perfluorophenylsulfonamido)propanamide	Investigative	44576806	C15H7F10N3O6S2	579.4	C(C(C(=O)NO)NS(=O)(=O)C1=C(C(=C(C(=C1F)F)F)F)F)NS(=O)(=O)C2=C(C(=C(C(=C2F)F)F)F)F	Ki = 212000 nM	Non binder
T54156	Matrix metalloproteinase-9	BSK63Q	Z-L-Leu-L-Phe-OMe	Investigative	13968141	C24H30N2O5	426.5	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)OC)NC(=O)OCC2=CC=CC=C2	IC50 > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	BW5FE4	1,3,2-Triguanidinoneamine	Investigative	11328354	C15H32N10O6	448.48	C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N=C(N)N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N=C(N)N)O)O)N=C(N)N	Ki > 300000 nM	Non binder
T54156	Matrix metalloproteinase-9	BY38MR	(4S,5S)-2-(4-Chloro-phenyl)-4-phenylsulfanyl-5-vinyl-4,5-dihydro-oxazole	Investigative	44394702	C17H14ClNOS	315.8	C=C[C@H]1[C@@H](N=C(O1)C2=CC=C(C=C2)Cl)SC3=CC=CC=C3	Ki > 200000 nM	Non binder
T54156	Matrix metalloproteinase-9	D00TRF	2-(benzyloxyamino)-N-hydroxyacetamide	Investigative	44423683	C9H12N2O3	196.2	C1=CC=C(C=C1)CONCC(=O)NO	IC50 = 256000 nM	Non binder
T54156	Matrix metalloproteinase-9	D05BMD	2-(4-chlorobenzyloxyamino)-N-hydroxyacetamide	Investigative	44423684	C9H11ClN2O3	230.65	C1=CC(=CC=C1CONCC(=O)NO)Cl	IC50 = 261000 nM	Non binder
T54156	Matrix metalloproteinase-9	D07VXX	2-(benzyloxyamino)-N-hydroxy-3-methylpentanamide	Investigative	16721024	C13H20N2O3	252.31	CCC(C)C(C(=O)NO)NOCC1=CC=CC=C1	IC50 = 352000 nM	Non binder