TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T56510 Apoptosis regulator Bcl-xL B35KMC 3-(3,4-Dimethoxyphenyl)-N-(4-phenoxyphenyl)sulfonylbenzamide Investigative 53473390 C27H23NO6S 489.5 COC1=C(C=C(C=C1)C2=CC(=CC=C2)C(=O)NS(=O)(=O)C3=CC=C(C=C3)OC4=CC=CC=C4)OC IC50 > 1000000 nM Non binder T56510 Apoptosis regulator Bcl-xL B38XUQ Benzo[b]thiophene-2-carboxylic acid Investigative 95864 C9H6O2S 178.21 C1=CC=C2C(=C1)C=C(S2)C(=O)O Ki = 230000 nM Non binder T56510 Apoptosis regulator Bcl-xL B69UQH 3,7-Dimethyl-benzofuran-2-carboxylic acid Investigative 3163284 C11H10O3 190.19 CC1=C2C(=CC=C1)C(=C(O2)C(=O)O)C Ki > 1000000 nM Non binder T56510 Apoptosis regulator Bcl-xL B85FXP Ent-17-Hydroxytrachyloban-18-oic acid Investigative 46907040 C20H30O3 318.4 C[C@]12CCC[C@@]([C@@H]1CC[C@@]34[C@H]2C[C@H]5[C@@H](C3)[C@]5(C4)CO)(C)C(=O)O IC50 = 220000 nM Non binder T56510 Apoptosis regulator Bcl-xL B9QLO8 3-Chloro-6-methylbenzo[b]thiophene-2-carboxylic acid Investigative 815185 C10H7ClO2S 226.68 CC1=CC2=C(C=C1)C(=C(S2)C(=O)O)Cl Ki = 230000 nM Non binder T56510 Apoptosis regulator Bcl-xL BFGE04 3-(1-Naphthylmethylsulfanyl)-1H-1,2,4-triazole Investigative 719016 C13H11N3S 241.31 C1=CC=C2C(=C1)C=CC=C2CSC3=NC=NN3 Ki > 1000000 nM Non binder T56510 Apoptosis regulator Bcl-xL BGM79E Ent-Trachyloban-18-oic acid Investigative 46907039 C20H30O2 302.5 C[C@]12CCC[C@@]([C@@H]1CC[C@@]34[C@H]2C[C@H]5[C@@H](C3)[C@]5(C4)C)(C)C(=O)O IC50 = 400000 nM Non binder T56510 Apoptosis regulator Bcl-xL BI3FC4 3-(4-Chloro-3,5-dimethylphenoxy)propanoic acid Investigative 22683787 C11H13ClO3 228.67 CC1=CC(=CC(=C1Cl)C)OCCC(=O)O Ki > 1000000 nM Non binder T56510 Apoptosis regulator Bcl-xL BN6X4G 7-Methyl-3-phenyl-1H-indole-2-carboxylic acid Investigative 16645886 C16H13NO2 251.28 CC1=C2C(=CC=C1)C(=C(N2)C(=O)O)C3=CC=CC=C3 Ki > 1000000 nM Non binder T56510 Apoptosis regulator Bcl-xL BU9D4O 3,6,7-Trimethyl-benzofuran-2-carboxylic acid Investigative 6484626 C12H12O3 204.22 CC1=C(C2=C(C=C1)C(=C(O2)C(=O)O)C)C Ki > 1000000 nM Non binder T56510 Apoptosis regulator Bcl-xL BUFB14 (4-Chloro-3-methylphenoxy)acetic acid Investigative 95696 C9H9ClO3 200.62 CC1=C(C=CC(=C1)OCC(=O)O)Cl Ki > 1000000 nM Non binder T56510 Apoptosis regulator Bcl-xL BW9PZ0 Ent-16alpha-Hydroxykaur-11-en-18-oic acid Investigative 46907075 C20H30O3 318.4 C[C@]12CCC[C@@]([C@@H]1CC[C@@]34[C@@H]2C=C[C@H](C3)[C@@](C4)(C)O)(C)C(=O)O IC50 = 380000 nM Non binder T56510 Apoptosis regulator Bcl-xL BZJ3W9 3,4-Dichloro-1-benzothiophene-2-carboxylic acid Investigative 819258 C9H4Cl2O2S 247.1 C1=CC2=C(C(=C1)Cl)C(=C(S2)C(=O)O)Cl Ki > 1000000 nM Non binder