TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T58178	Glutamate receptor ionotropic kainate 2	B2WLD9	(3S,4Ar,6S,8aR)-6-[(4-carboxyimidazol-1-yl)methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid;dihydrochloride	Investigative	45262167	C15H23Cl2N3O4	380.3	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1CN3C=C(N=C3)C(=O)O)C(=O)O.Cl.Cl	Ki = 236000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	B5OED9	(2r)-2-Amino-3-(4-Hydroxy-1,2,5-Thiadiazol-3-Yl)propanoic Acid	Investigative	10420002	C5H7N3O3S	189.2	C(C1=NSNC1=O)[C@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	B5OLU0	4-Isopropylidene-L-glutamic acid	Investigative	44296602	C8H13NO4	187.19	CC(=C(C[C@@H](C(=O)O)N)C(=O)O)C	Ki > 400000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	B5ZSG4	(S)-2-Amino-4-(1-ethyl-propylidene)-pentanedioic acid	Investigative	10398361	C10H17NO4	215.25	CCC(=C(C[C@@H](C(=O)O)N)C(=O)O)CC	Ki = 207000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	B9J2RD	4-Cyclohexylidene-L-glutamic acid	Investigative	44296812	C11H17NO4	227.26	C1CCC(=C(C[C@@H](C(=O)O)N)C(=O)O)CC1	Ki = 255000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	BDL9T8	4-[(E)-3-Methylbutylidene]-L-glutamic acid	Investigative	44296375	C10H17NO4	215.25	CC(C)C/C=C(\\C[C@@H](C(=O)O)N)/C(=O)O	Ki = 634000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	BEW9B8	4-Propylidene-L-glutamic acid	Investigative	15347044	C8H13NO4	187.19	CC/C=C(/C[C@@H](C(=O)O)N)\\C(=O)O	EC50 > 300000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	BOQ7Z1	(2S,4Z)-2-Amino-4-(2-methylpropylidene)pentanedioic Acid	Investigative	11820131	C9H15NO4	201.22	CC(C)/C=C(/C[C@@H](C(=O)O)N)\\C(=O)O	Ki > 500000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	BVQ46S	4-[(E)-3-Phenylpropylidene]-L-glutamic acid	Investigative	44296601	C14H17NO4	263.29	C1=CC=C(C=C1)CC/C=C(\\C[C@@H](C(=O)O)N)/C(=O)O	Ki = 205000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	D09VYB	UBP-302	Investigative	6420161	C15H15N3O6	333.3	C1=CC=C(C(=C1)CN2C(=O)C=CN(C2=O)C[C@@H](C(=O)O)N)C(=O)O	IC50 > 300000 nM	Non binder
T58178	Glutamate receptor ionotropic kainate 2	D0T5SU	(S)-AMPA	Investigative	158397	C7H10N2O4	186.17	CC1=C(C(=O)NO1)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder