TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T59102	Platelet-derived growth factor receptor beta	D08CDI	Lapatinib	Approved	208908	C29H26ClFN4O4S	581.1	CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B18RDA	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[2-methylsulfonyl-1-(propan-2-ylamino)ethyl]furan-2-yl]quinazolin-4-amine	Investigative	118717615	C31H30ClFN4O4S	609.1	CC(C)NC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B1D2BK	2-Amino-4-(N-methyl-m-bromoanilino)-6-(2,5-dimethoxybenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine	Investigative	46912546	C23H24BrN5O2	482.4	CN1C(=CC2=C1N=C(N=C2N(C)C3=CC(=CC=C3)Br)N)CC4=C(C=CC(=C4)OC)OC	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B1JZB8	N-[4-(3-Ethynylanilino)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide	Investigative	71525285	C26H26N6O	438.5	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC=CC(=C4)C#C	IC50 = 430100 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B2CL6O	N-(3-Bromophenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887111	C19H13BrCl2N4	448.1	C1=CC(=CC(=C1)Br)NC2=NC=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl	IC50 = 220400 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B2GI7T	[[(1S)-1-[5-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-yl]-2-methylsulfonylethyl]amino] propanoate	Investigative	118717617	C31H28ClFN4O6S	639.1	CCC(=O)ON[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B2JB4R	2,4-Diaminofuro[2,3-d]pyrimidine, 8	Investigative	44246325	C18H22N4O2	326.4	CCCC(CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B35AQR	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(ethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	56640588	C30H28ClFN4O4S	595.1	CCNC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B37AVZ	N-[5-Chloro-4-(4-chloroanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide	Investigative	71583532	C21H19Cl2N5O	428.3	CC(C)(C)C(=O)NC1=NC2=C(C3=C(N2)C=CC=C3Cl)C(=N1)NC4=CC=C(C=C4)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B3M9AQ	N-(4-Chloro-2-fluorophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887349	C20H16ClFN4	366.8	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=C(C=C(C=C4)Cl)F	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B3QX6N	4-N-(3-Ethynylphenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	71525247	C21H18N6	354.4	C#CC1=CC(=CC=C1)NC2=NC(=NC3=C2C=C(N3)CCC4=CC=CC=N4)N	IC50 = 331500 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B3Z1IA	N4-(3-Chloro-4-fluorophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586490	C20H17ClFN5	381.8	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)Cl)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B4H7TR	[[(1S)-1-[5-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-yl]-2-methylsulfonylethyl]amino] pentanoate	Investigative	118717618	C33H32ClFN4O6S	667.1	CCCCC(=O)ON[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B4ND6W	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[2-methylsulfonyl-1-(2-methylsulfonylethylamino)ethyl]furan-2-yl]quinazolin-4-amine	Investigative	118717616	C31H30ClFN4O6S2	673.2	CS(=O)(=O)CCNC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B52FED	N-(3-Ethynylphenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887298	C22H18N4	338.4	C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C(N3)CCC4=CC=CC=C4	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B5JP4Y	6-[5-(1-Amino-2-methylsulfonylethyl)furan-2-yl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine	Investigative	56640590	C28H24ClFN4O4S	567	CS(=O)(=O)CC(C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B5UOP1	4-N-(3-Bromophenyl)-7-[(4-chlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394880	C19H15BrClN5	428.7	C1=CC(=CC(=C1)Br)NC2=C3C=CN(C3=NC(=N2)N)CC4=CC=C(C=C4)Cl	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B5XGQ0	2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-pyrrolo[2,3-d]pyrimidine	Investigative	52948634	C20H18BrN5	408.3	CN(C1=CC(=CC=C1)Br)C2=NC(=NC3=C2C=C(N3)CC4=CC=CC=C4)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B5XSL9	N4-(3-Fluoro-4-trifluoromethylphenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46886974	C20H13Cl2F4N5	470.2	C1=CC(=C(C=C1NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N)F)C(F)(F)F	IC50 > 300000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B7WA1P	6-(2-Phenylethyl)-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887299	C21H17F3N4	382.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC=CC(=C4)C(F)(F)F	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B82QDO	2-Amino-4-(N-methyl-m-bromoanilino)-6-(2-methylbenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine	Investigative	46912445	C22H22BrN5	436.3	CC1=CC=CC=C1CC2=CC3=C(N2C)N=C(N=C3N(C)C4=CC(=CC=C4)Br)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B8NWY1	5-[2-Cyclopropyl-2-(2-methoxyphenyl)ethenyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52947802	C18H18N4O2	322.4	COC1=CC=CC=C1C(=CC2=COC3=NC(=NC(=C23)N)N)C4CC4	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B8T1KO	7-Benzyl-4-N-(3-bromophenyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394879	C19H16BrN5	394.3	C1=CC=C(C=C1)CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B8T6XU	5-Chloro-4-N-phenyl-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	71583411	C16H12ClN5	309.75	C1=CC=C(C=C1)NC2=NC(=NC3=C2C4=C(N3)C=CC=C4Cl)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B8V5AJ	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(cyclohexylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	118717614	C34H34ClFN4O4S	649.2	CS(=O)(=O)CC(C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)NC6CCCCC6	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	B8YC0L	CID 46866615	Investigative	46866615	C28H24ClFN4O4S	567	CS(=O)(=O)C[C@@H](C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BCLV75	[[(1S)-1-[5-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-yl]-2-methylsulfonylethyl]amino] heptanoate	Investigative	118717619	C35H36ClFN4O6S	695.2	CCCCCCC(=O)ON[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BCS86E	4-N-(4-Chloro-2-fluorophenyl)-6-(naphthalen-1-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	56951305	C23H17ClFN5	417.9	C1=CC=C2C(=C1)C=CC=C2CC3=CC4=C(N3)N=C(N=C4NC5=C(C=C(C=C5)Cl)F)N	IC50 > 300000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BD1BX0	N-[4-(3-Chloro-4-fluoroanilino)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide	Investigative	71525284	C24H24ClFN6O	466.9	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC(=C(C=C4)F)Cl	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BE2K7Z	5-[2-(2-Methoxyphenyl)-3-methylpent-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52945403	C19H22N4O2	338.4	CCC(C)C(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BEQ2A7	2,4-Diaminofuro[2,3-d]pyrimidine, 10	Investigative	44246327	C18H20N4O2	324.4	COC1=CC=CC=C1C(CC2=COC3=NC(=NC(=C23)N)N)C4CC4	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BFOR28	N-[4-[4-Fluoro-3-(trifluoromethyl)anilino]-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide	Investigative	71525287	C25H24F4N6O	500.5	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC(=C(C=C4)F)C(F)(F)F	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BFQ9N7	6-(2-Pyridin-2-ylethyl)-4-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	71525248	C20H17F3N6	398.4	C1=CC=NC(=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC=CC(=C4)C(F)(F)F)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BHX37J	2-Amino-4-(m-bromoanilino)-6-(2-methylbenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine	Investigative	52949915	C21H20BrN5	422.3	CC1=CC=CC=C1CC2=CC3=C(N=C(N=C3N2C)N)NC4=CC(=CC=C4)Br	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BI1B6L	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(1R)-1-(dimethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	46865445	C30H28ClFN4O4S	595.1	CN(C)[C@@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BI1HX2	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(1S)-1-(dimethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	46865125	C30H28ClFN4O4S	595.1	CN(C)[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BJ57YZ	N-(4-Methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine	Investigative	50908681	C19H16N2O2	304.3	COC1=CC=C(C=C1)CNC2=C3C4=CC=CC=C4OC3=NC=C2	Ki > 1000000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BL1Z0K	N4-(3-Bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	3008962	C21H20BrN5O2	454.3	COC1=CC(=C(C=C1)OC)CC2=CC3=C(N2)N=C(N=C3NC4=CC(=CC=C4)Br)N	IC50 > 300000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BMEZ71	4-N-[4-Fluoro-3-(trifluoromethyl)phenyl]-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	71525249	C20H16F4N6	416.4	C1=CC=NC(=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)C(F)(F)F)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BN07JT	5-(2,5-Dimethoxyphenyl)sulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	137633842	C18H17N5O2S	367.4	COC1=CC(=C(C=C1)OC)SC2=CC=CC3=C2C4=C(N=C(N=C4N3)N)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BND9X0	6-Phenethyl-N4-(3-(trifluoromethyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	25022736	C21H18F3N5	397.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC=CC(=C4)C(F)(F)F)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BNJM48	2,2-Dimethyl-N-[6-(2-pyridin-2-ylethyl)-4-[3-(trifluoromethyl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]propanamide	Investigative	71525286	C25H25F3N6O	482.5	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC=CC(=C4)C(F)(F)F	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BOD1W4	CID 46866616	Investigative	46866616	C28H24ClFN4O4S	567	CS(=O)(=O)C[C@H](C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BOHV12	4-N-(3-Bromo-4-fluorophenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	71525245	C19H16BrFN6	427.3	C1=CC=NC(=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)Br)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BOMZ50	2,4-Diaminofuro[2,3-d]pyrimidine, 12	Investigative	44246329	C19H24N4O2	340.4	CC(C)CC(CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BPL8M1	2-Amino-4-(m-bromoanilino)-6-(2,5-dimethoxybenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine	Investigative	52947574	C22H22BrN5O2	468.3	CN1C(=CC2=C(N=C(N=C21)N)NC3=CC(=CC=C3)Br)CC4=C(C=CC(=C4)OC)OC	IC50 = 348000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BPLH59	4-N-(3-Bromophenyl)-7-[(3,4-dichlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57398331	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=C3C=CN(C3=NC(=N2)N)CC4=CC(=C(C=C4)Cl)Cl	IC50 = 229600 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BQ16DR	N4-(4-Chloro-2-fluorophenyl)-6-(2-phenylethyl)-7Hpyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586527	C20H17ClFN5	381.8	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Cl)F)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BQR5H8	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(methylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	56640518	C29H26ClFN4O4S	581.1	CNC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BR2X5W	N-[5-Chloro-4-(3-fluoroanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide	Investigative	71583634	C21H19ClFN5O	411.9	CC(C)(C)C(=O)NC1=NC2=C(C3=C(N2)C=CC=C3Cl)C(=N1)NC4=CC(=CC=C4)F	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BS0W1X	6-[(2,4-Dichlorophenyl)methyl]-4-N-(3-ethynylphenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46886973	C21H15Cl2N5	408.3	C#CC1=CC(=CC=C1)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N	IC50 > 300000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BS6A5G	5-Chloro-4-N-(4-propan-2-ylphenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	71583412	C19H18ClN5	351.8	CC(C)C1=CC=C(C=C1)NC2=NC(=NC3=C2C4=C(N3)C=CC=C4Cl)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BS9TZ1	N-[4-Fluoro-3-(trifluoromethyl)phenyl]-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887348	C21H16F4N4	400.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC(=C(C=C4)F)C(F)(F)F	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BSA7P5	5-Chloro-4-N-(4-chloro-2-fluorophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	71583528	C16H10Cl2FN5	362.2	C1=CC2=C(C(=C1)Cl)C3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Cl)F)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BSIO95	2,4-Diaminofuro[2,3-d]pyrimidine, 11	Investigative	44246328	C19H24N4O2	340.4	CCCCC(CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BSN8Z0	N-[5-Chloro-4-(4-propan-2-ylanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide	Investigative	71583531	C24H26ClN5O	435.9	CC(C)C1=CC=C(C=C1)NC2=NC(=NC3=C2C4=C(N3)C=CC=C4Cl)NC(=O)C(C)(C)C	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BTIG04	4-N-(3-Chloro-4-fluorophenyl)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	71525246	C19H16ClFN6	382.8	C1=CC=NC(=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)Cl)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BTQ70E	5-[2-(2-Methoxyphenyl)-4-methylpent-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52946619	C19H22N4O2	338.4	CC(C)CC(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BU2D0R	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(dimethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	56640520	C30H28ClFN4O4S	595.1	CN(C)C(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BU71CV	5-(4-Chlorophenyl)sulfanyl-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	137652218	C16H12ClN5S	341.8	C1=CC2=C(C(=C1)SC3=CC=C(C=C3)Cl)C4=C(N=C(N=C4N2)N)N	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BV5N2G	5-[2-(2-Methoxyphenyl)-3-methylbut-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52942956	C18H20N4O2	324.4	CC(C)C(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BVG59H	5-[2-(2-Methoxyphenyl)hex-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52947801	C19H22N4O2	338.4	CCCCC(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BW1NE7	N4-(4-Bromo-2-chlorophenyl)-6-(2,4-dichlorobenzyl)-7Hpyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46845026	C19H13BrCl3N5	497.6	C1=CC(=C(C=C1Cl)Cl)CC2=CC3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Br)Cl)N	IC50 > 300000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BW3S6G	6-[(2,4-Dichlorophenyl)methyl]-4-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46886972	C20H14Cl2F3N5	452.3	C1=CC(=CC(=C1)NC2=NC(=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl)N)C(F)(F)F	IC50 > 300000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BW53EL	4-N-(3-Bromophenyl)-7-(naphthalen-2-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57396545	C23H18BrN5	444.3	C1=CC=C2C=C(C=CC2=C1)CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 = 212400 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BXY0S7	4-N-(4-Chlorophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586528	C20H18ClN5	363.8	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC=C(C=C4)Cl)N	IC50 > 500000 nM	Non binder
T59102	Platelet-derived growth factor receptor beta	BZ2AF9	N4-(3-Bromo-4-fluorophenyl)-6-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	10251852	C20H17BrFN5	426.3	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)Br)N	IC50 > 500000 nM	Non binder