TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T59328	Epidermal growth factor receptor	D08HVR	Levodopa	Approved	6047	C9H11NO4	197.19	C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O	IC50 = 900000 nM	Non binder
T59328	Epidermal growth factor receptor	D00BPA	Olomoucine	Terminated	4592	C15H18N6O	298.34	CN1C=NC2=C(N=C(N=C21)NCCO)NCC3=CC=CC=C3	IC50 = 440000 nM	Non binder
T59328	Epidermal growth factor receptor	B02HCT	N-[4-(3-Bromoanilino)-3-cyanoquinolin-6-yl]-4-(propan-2-ylamino)but-2-ynamide	Investigative	76312208	C23H20BrN5O	462.3	CC(C)NCC#CC(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=CC=C3)Br	IC50 = 250034.54 nM	Non binder
T59328	Epidermal growth factor receptor	B0DB6N	N-[5-Chloro-4-(4-chloro-2-fluoroanilino)-9H-pyrimido[4,5-b]indol-2-yl]-2,2-dimethylpropanamide	Investigative	71583533	C21H18Cl2FN5O	446.3	CC(C)(C)C(=O)NC1=NC2=C(C3=C(N2)C=CC=C3Cl)C(=N1)NC4=C(C=C(C=C4)Cl)F	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B0QN7J	13-(1,3-Dihydroxypropan-2-ylamino)-5,21-dihydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273560	C29H28N4O11	608.6	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC(CO)CO)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B0RQ8G	2-((3,5-Dimethyl-4-hydroxyphenyl)-methylene)-4-cyclopentene-1,3-dione	Investigative	6419746	C14H12O3	228.24	CC1=CC(=CC(=C1O)C)C=C2C(=O)C=CC2=O	IC50 = 440000 nM	Non binder
T59328	Epidermal growth factor receptor	B0SFH5	4-N-(4-Chlorophenyl)-6-[(2-methylphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	56951307	C20H18ClN5	363.8	CC1=CC=CC=C1CC2=CC3=C(N2)N=C(N=C3NC4=CC=C(C=C4)Cl)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B14FAH	N-(3-Bromo-4-fluorophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887300	C20H16BrFN4	411.3	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC(=C(C=C4)F)Br	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B14PIX	N-[4-(3-Bromoanilino)-3-cyano-7-methoxyquinolin-6-yl]-4-methoxybut-2-ynamide	Investigative	10161969	C22H17BrN4O3	465.3	COCC#CC(=O)NC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=CC=C3)Br)OC	IC50 = 790678.63 nM	Non binder
T59328	Epidermal growth factor receptor	B1JZB8	N-[4-(3-Ethynylanilino)-6-(2-pyridin-2-ylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]-2,2-dimethylpropanamide	Investigative	71525285	C26H26N6O	438.5	CC(C)(C)C(=O)NC1=NC2=C(C=C(N2)CCC3=CC=CC=N3)C(=N1)NC4=CC=CC(=C4)C#C	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B1OUQ8	Benzylidenemalononitrile (BMN) deriv. 40	Investigative	5328797	C12H9N3O2	227.22	C1=CC(=CC=C1/C=C(\\C#N)/C(=O)NCC#N)O	Ki = 360000 nM	Non binder
T59328	Epidermal growth factor receptor	B1URH2	2-(1H-Pyrrol-2-ylmethylene)malononitrile	Investigative	2795373	C8H5N3	143.15	C1=CNC(=C1)C=C(C#N)C#N	IC50 = 260000 nM	Non binder
T59328	Epidermal growth factor receptor	B20KXH	Edotecarin	Investigative	9808998	C29H28N4O11	608.6	C1=CC2=C(C=C1O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC(CO)CO)C6=C(N4[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C=C(C=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B21UJN	4-N-(3-Bromophenyl)-7-[(4-phenylphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57391283	C25H20BrN5	470.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B26CIX	US9422297, Aag145-341	Investigative	129625875	C17H13BrN4	353.2	C1C2=CC=CC=C2C3=C1C(=NC(=N3)N)NC4=CC=C(C=C4)Br	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	B2CL6O	N-(3-Bromophenyl)-6-(2,4-dichlorobenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887111	C19H13BrCl2N4	448.1	C1=CC(=CC(=C1)Br)NC2=NC=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	B2N0EW	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]acetamide	Investigative	44273654	C28H24N4O10	576.5	CC(=O)NN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B34AOF	US9422297, Aag145-347	Investigative	129625878	C17H13FN4	292.31	C1C2=CC=CC=C2C3=C1C(=NC(=N3)N)NC4=CC=C(C=C4)F	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	B3AK4M	2-(4-Hydroxyphenyl)benzothiazole-4,6-diol	Investigative	135511836	C13H9NO3S	259.279	C1=CC(=CC=C1C2=NC3=C(C=C(C=C3S2)O)O)O	IC50 = 300000 nM	Non binder
T59328	Epidermal growth factor receptor	B3M9AQ	N-(4-Chloro-2-fluorophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887349	C20H16ClFN4	366.8	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=C(C=C(C=C4)Cl)F	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B3WU8B	Propanedinitrile, 2-[[(4-hydroxyphenyl)amino]methylene]-	Investigative	5328814	C10H7N3O	185.18	C1=CC(=CC=C1NC=C(C#N)C#N)O	IC50 = 350000 nM	Non binder
T59328	Epidermal growth factor receptor	B3ZC6X	13-(Ethylamino)-5,21-dihydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273491	C28H26N4O9	562.5	CCNN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B4AC8G	4-N-(3-Bromophenyl)-7-[(3,4,5-trimethoxyphenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57384106	C22H22BrN5O3	484.3	COC1=CC(=CC(=C1OC)OC)CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B4E6UF	N-[4-Methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide	Investigative	71496459	C27H31N7O2	485.6	CNCCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C)OC	IC50 = 786000 nM	Non binder
T59328	Epidermal growth factor receptor	B4GVJ9	3-[[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]amino]propanenitrile	Investigative	44273598	C29H25N5O9	587.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NCCC#N)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B4OXM9	N-[4-(3-Bromoanilino)-3-cyanoquinolin-6-yl]-4-thiomorpholin-4-ylbut-2-ynamide	Investigative	11762902	C24H20BrN5OS	506.4	C1CSCCN1CC#CC(=O)NC2=CC3=C(C(=CN=C3C=C2)C#N)NC4=CC(=CC=C4)Br	IC50 = 550047.25 nM	Non binder
T59328	Epidermal growth factor receptor	B4SMP2	US9422297, Aag145-344	Investigative	57608010	C17H14N4	274.32	C1C2=CC=CC=C2C3=C1C(=NC(=N3)N)NC4=CC=CC=C4	IC50 = 232700 nM	Non binder
T59328	Epidermal growth factor receptor	B52FED	N-(3-Ethynylphenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887298	C22H18N4	338.4	C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C(N3)CCC4=CC=CC=C4	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B5GDO4	2-(4-Hydroxy-3,5-dimethoxyphenyl)ethene-1,1,2-tricarbonitrile	Investigative	44576151	C13H9N3O3	255.23	COC1=CC(=CC(=C1O)OC)C(=C(C#N)C#N)C#N	IC50 = 900000 nM	Non binder
T59328	Epidermal growth factor receptor	B5L1YD	5-Chloro-4-N-(3-fluorophenyl)-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	71583529	C16H11ClFN5	327.74	C1=CC(=CC(=C1)F)NC2=NC(=NC3=C2C4=C(N3)C=CC=C4Cl)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B5Q8LZ	2-[(4-Fluorophenyl)methylidene]propanedinitrile	Investigative	367524	C10H5FN2	172.16	C1=CC(=CC=C1C=C(C#N)C#N)F	Ki > 400000 nM	Non binder
T59328	Epidermal growth factor receptor	B63GCS	2-(3-Hydroxyphenyl)ethene-1,1,2-tricarbonitrile	Investigative	44576154	C11H5N3O	195.18	C1=CC(=CC(=C1)O)C(=C(C#N)C#N)C#N	IC50 = 400000 nM	Non binder
T59328	Epidermal growth factor receptor	B64DXM	13-(Dimethylamino)-5,21-dihydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273527	C28H26N4O9	562.5	CN(C)N1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B6HR5T	2-[(3-Hydroxy-4-methoxyphenyl)methylidene]propanedinitrile	Investigative	694921	C11H8N2O2	200.19	COC1=C(C=C(C=C1)C=C(C#N)C#N)O	IC50 > 250000 nM	Non binder
T59328	Epidermal growth factor receptor	B6XQV0	Benzylidenemalononitrile (BMN) deriv. 41	Investigative	5328798	C15H13N3O3	283.28	CC(=C(C#N)C#N)C1=CC=C(C=C1)NC(=O)CCC(=O)O	IC50 = 500000 nM	Non binder
T59328	Epidermal growth factor receptor	B71RQD	N-(4-(2,2-Dicyanovinyl)phenyl)acetamide	Investigative	33296	C12H9N3O	211.22	CC(=O)NC1=CC=C(C=C1)C=C(C#N)C#N	IC50 > 325000 nM	Non binder
T59328	Epidermal growth factor receptor	B7A4TE	Benzylidenemalononitrile (BMN) deriv. 5	Investigative	5328782	C14H11N3O3	269.25	C1=CC(=CC=C1C=C(C#N)C#N)NC(=O)CCC(=O)O	Ki = 240000 nM	Non binder
T59328	Epidermal growth factor receptor	B7M0KI	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]formamide	Investigative	17874201	C27H22N4O10	562.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC=O)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B7WA1P	6-(2-Phenylethyl)-N-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887299	C21H17F3N4	382.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC=CC(=C4)C(F)(F)F	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B83YSQ	6,20-Dihydroxy-13-[[3-(hydroxymethyl)pyridin-4-yl]methylamino]-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44565965	C33H29N5O11	671.6	C1=CC2=C(C=C1O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NCC6=C(C=NC=C6)CO)C7=C(N4O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C=C(C=C7)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B8K5UO	2-(4-Hydroxy-3-methoxy-5-phenylsulfanylmethyl-benzylidene)-malononitrile	Investigative	44345469	C18H14N2O2S	322.4	COC1=CC(=CC(=C1O)CSC2=CC=CC=C2)C=C(C#N)C#N	IC50 = 370000 nM	Non binder
T59328	Epidermal growth factor receptor	B8MF5X	N-(3-Bromophenyl)-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887255	C20H17BrN4	393.3	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC(=CC=C4)Br	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B8NWY1	5-[2-Cyclopropyl-2-(2-methoxyphenyl)ethenyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52947802	C18H18N4O2	322.4	COC1=CC=CC=C1C(=CC2=COC3=NC(=NC(=C23)N)N)C4CC4	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B8T4EG	N-[4-(3-Bromoanilino)-3-cyanoquinolin-6-yl]-4-methoxybut-2-ynamide	Investigative	10884588	C21H15BrN4O2	435.3	COCC#CC(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=CC=C3)Br	IC50 = 960063.59 nM	Non binder
T59328	Epidermal growth factor receptor	B8T6XU	5-Chloro-4-N-phenyl-9H-pyrimido[4,5-b]indole-2,4-diamine	Investigative	71583411	C16H12ClN5	309.75	C1=CC=C(C=C1)NC2=NC(=NC3=C2C4=C(N3)C=CC=C4Cl)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B8VQU0	[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]urea	Investigative	44273561	C27H23N5O10	577.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC(=O)N)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	B9J2ED	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]propanamide	Investigative	44273646	C29H26N4O10	590.5	CCC(=O)NN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BA48GY	6,20-Dihydroxy-13-[[6-(hydroxymethyl)pyridin-2-yl]methylamino]-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44565958	C33H29N5O11	671.6	C1=CC(=NC(=C1)CO)CNN2C(=O)C3=C4C5=C(C=C(C=C5)O)NC4=C6C(=C3C2=O)C7=C(N6O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C=C(C=C7)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BAW04S	4-N-(3-Bromophenyl)-7-[(2,4-dichlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394786	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=C3C=CN(C3=NC(=N2)N)CC4=C(C=C(C=C4)Cl)Cl	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BB14PH	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]pyridine-2-carboxamide	Investigative	44273652	C32H25N5O10	639.6	C1=CC=NC(=C1)C(=O)NN2C(=O)C3=C4C5=C(C(=CC=C5)O)NC4=C6C(=C3C2=O)C7=C(N6C8C(C(C(C(O8)CO)O)O)O)C(=CC=C7)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BB2S7Q	2-Amino-4-(N-methyl-m-bromoanilino)-6-benzyl-7-methyl-pyrrolo[2,3-d]pyrimidine	Investigative	52941368	C21H20BrN5	422.3	CN1C(=CC2=C1N=C(N=C2N(C)C3=CC(=CC=C3)Br)N)CC4=CC=CC=C4	IC50 = 253600 nM	Non binder
T59328	Epidermal growth factor receptor	BBEH31	N4-(3-Ethynylphenyl)-6-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586526	C22H19N5	353.4	C#CC1=CC(=CC=C1)NC2=NC(=NC3=C2C=C(N3)CCC4=CC=CC=C4)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BBQ9K5	N-[4-(3-Chloro-4-fluoro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-2-dimethylaminomethyl-acrylamide	Investigative	10972694	C24H23ClFN5O2	467.9	CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)C(=C)CN(C)C	IC50 = 560015.44 nM	Non binder
T59328	Epidermal growth factor receptor	BC4I5Z	Propanedinitrile, ((4-methoxyphenyl)hydrazono)-	Investigative	121059	C10H8N4O	200.2	COC1=CC=C(C=C1)NN=C(C#N)C#N	IC50 = 600000 nM	Non binder
T59328	Epidermal growth factor receptor	BCK87Y	4-Dimethylamino-but-2-enoic acid [4-(3-bromo-phenylamino)-3-cyano-quinolin-6-yl]-amide	Investigative	10253204	C22H20BrN5O	450.3	CN(C)C/C=C/C(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=CC=C3)Br	IC50 = 310027.34 nM	Non binder
T59328	Epidermal growth factor receptor	BD01VJ	(E)-3-[3-Tert-butyl-4-hydroxy-5-[(2-methylpropan-2-yl)oxy]phenyl]-2-cyanoprop-2-enethioamide	Investigative	136130281	C18H24N2O2S	332.5	CC(C)(C)C1=C(C(=CC(=C1)/C=C(\\C#N)/C(=S)N)OC(C)(C)C)O	IC50 = 501187.23 nM	Non binder
T59328	Epidermal growth factor receptor	BE2K7Z	5-[2-(2-Methoxyphenyl)-3-methylpent-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52945403	C19H22N4O2	338.4	CCC(C)C(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BE42RB	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]methanesulfonamide	Investigative	44273700	C27H24N4O11S	612.6	CS(=O)(=O)NN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BE8J6B	2-[(6-Nitro-1,3-benzodioxol-5-yl)methylidene]propanedinitrile	Investigative	707914	C11H5N3O4	243.17	C1OC2=C(O1)C=C(C(=C2)C=C(C#N)C#N)[N+](=O)[O-]	IC50 = 560000 nM	Non binder
T59328	Epidermal growth factor receptor	BEJ62B	4-Phenyl-[1]benzofuro[2,3-b]pyridine-3,6-diol	Investigative	51000510	C17H11NO3	277.27	C1=CC=C(C=C1)C2=C3C4=C(C=CC(=C4)O)OC3=NC=C2O	Ki = 296000 nM	Non binder
T59328	Epidermal growth factor receptor	BEPM92	4-Methoxymethoxy-but-2-ynoic acid[4-(3-bromophenylamino)-3-cyano-quinolin-6-yl]-amide	Investigative	11016075	C22H17BrN4O3	465.3	COCOCC#CC(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=CC=C3)Br	IC50 = 330065.4 nM	Non binder
T59328	Epidermal growth factor receptor	BF2MS6	5-(2,2-Dicyanoethenyl)furan-2-sulfonic acid sodium salt	Investigative	5328744	C8H3N2NaO4S	246.18	C1=C(OC(=C1)S(=O)(=O)[O-])C=C(C#N)C#N.[Na+]	IC50 > 250000 nM	Non binder
T59328	Epidermal growth factor receptor	BFA5Z3	6,20-Dihydroxy-13-(pyridin-4-ylmethylamino)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44565943	C32H27N5O10	641.6	C1=CC2=C(C=C1O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NCC6=CC=NC=C6)C7=C(N4O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)C=C(C=C7)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BFH4K2	2-[(3,5-Ditert-butyl-4-hydroxyphenyl)methylidene]cyclopent-4-ene-1,3-dione	Investigative	403661	C20H24O3	312.4	CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C2C(=O)C=CC2=O	IC50 = 320000 nM	Non binder
T59328	Epidermal growth factor receptor	BG3I4H	N-[2-[3-(Dimethylamino)azetidine-1-yl]-4-methoxy-5-[4-(pyrazolo[1,5-a]pyridine-3-yl)-5-chloropyrimidine-2-ylamino]phenyl]acrylamide	Investigative	101884761	C26H27ClN8O2	519	CN(C)C1CN(C1)C2=CC(=C(C=C2NC(=O)C=C)NC3=NC=C(C(=N3)C4=C5C=CC=CN5N=C4)Cl)OC	IC50 = 938000 nM	Non binder
T59328	Epidermal growth factor receptor	BG3S1X	2-[[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]amino]acetic acid	Investigative	44273617	C28H24N4O11	592.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NCC(=O)O)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BG9NK1	alpha-Cyanocinnamic acid	Investigative	643159	C10H7NO2	173.17	C1=CC=C(C=C1)/C=C(\\C#N)/C(=O)O	IC50 = 850000 nM	Non binder
T59328	Epidermal growth factor receptor	BHB93A	2,4-Diaminofuro[2,3-d]pyrimidine, 13	Investigative	44246330	C19H24N4O2	340.4	CCC(C)C(CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BHC91P	2-(Hydroxy(4-Hydroxyphenyl)Methylene)Malononitrile	Investigative	5328800	C10H6N2O2	186.17	C1=CC(=CC=C1C(=C(C#N)C#N)O)O	IC50 = 230000 nM	Non binder
T59328	Epidermal growth factor receptor	BHL5T8	2-[(4-Hydroxy-3,5-dimethoxyphenyl)methylidene]propanedinitrile	Investigative	746495	C12H10N2O3	230.22	COC1=CC(=CC(=C1O)OC)C=C(C#N)C#N	Ki = 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BI73CN	1-Carboxy-1-cyano-2-(4-fluorophenyl)ethylene	Investigative	1550170	C10H6FNO2	191.16	C1=CC(=CC=C1/C=C(\\C#N)/C(=O)O)F	IC50 = 833000 nM	Non binder
T59328	Epidermal growth factor receptor	BIA57B	6-(2,4-Dichlorobenzyl)-N-(3-ethynylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887113	C21H14Cl2N4	393.3	C#CC1=CC(=CC=C1)NC2=NC=NC3=C2C=C(N3)CC4=C(C=C(C=C4)Cl)Cl	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BISN58	2-(2-Oxoindolin-3-ylidene)malononitrile	Investigative	244537	C11H5N3O	195.18	C1=CC=C2C(=C1)C(=C(C#N)C#N)C(=O)N2	IC50 > 250000 nM	Non binder
T59328	Epidermal growth factor receptor	BJ0PI1	5,21-Dihydroxy-13-[(3-hydroxyphenyl)methylamino]-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273599	C33H28N4O10	640.6	C1=CC(=CC(=C1)O)CNN2C(=O)C3=C4C5=C(C(=CC=C5)O)NC4=C6C(=C3C2=O)C7=C(N6C8C(C(C(C(O8)CO)O)O)O)C(=CC=C7)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BJC20B	5,21-Dihydroxy-13-(2-hydroxyethylamino)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273597	C28H26N4O10	578.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NCCO)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BK1VI4	N4-1H-Indol-5-yl-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	44586577	C22H20N6	368.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC5=C(C=C4)NC=C5)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BK93ED	Propanedinitrile, [(4-hydroxyphenyl)hydrazono]-	Investigative	5328813	C9H6N4O	186.17	C1=CC(=CC=C1NN=C(C#N)C#N)O	IC50 = 225000 nM	Non binder
T59328	Epidermal growth factor receptor	BL8MK2	N-[4-[(3-Bromophenyl)amino]-3-cyano-6-quinolinyl]butynamide	Investigative	9887521	C20H13BrN4O	405.2	CC#CC(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=CC=C3)Br	IC50 = 940156.17 nM	Non binder
T59328	Epidermal growth factor receptor	BLV63S	Malononitrile, (4-pyridylmethylene)-	Investigative	44390	C9H5N3	155.16	C1=CN=CC=C1C=C(C#N)C#N	IC50 = 250000 nM	Non binder
T59328	Epidermal growth factor receptor	BLWT51	(4-Morpholin-4-ylbenzylidene)malononitrile	Investigative	321779	C14H13N3O	239.27	C1COCCN1C2=CC=C(C=C2)C=C(C#N)C#N	Ki > 250000 nM	Non binder
T59328	Epidermal growth factor receptor	BM2R3B	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]-2-(dimethylamino)acetamide	Investigative	44273623	C30H29N5O10	619.6	CN(C)CC(=O)NN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BN08XE	(2E)-2-Cyano-3-(4-hydroxyphenyl)prop-2-enamide	Investigative	5328796	C10H8N2O2	188.18	C1=CC(=CC=C1/C=C(\\C#N)/C(=O)N)O	IC50 = 800000 nM	Non binder
T59328	Epidermal growth factor receptor	BN3U2K	alpha-Cyano-4-methoxycinnamic acid	Investigative	736236	C11H9NO3	203.19	COC1=CC=C(C=C1)/C=C(\\C#N)/C(=O)O	IC50 = 833000 nM	Non binder
T59328	Epidermal growth factor receptor	BN46LB	Malononitrile, (3-pyridylmethylene)-	Investigative	23905	C9H5N3	155.16	C1=CC(=CN=C1)C=C(C#N)C#N	IC50 = 225000 nM	Non binder
T59328	Epidermal growth factor receptor	BND9X0	6-Phenethyl-N4-(3-(trifluoromethyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	25022736	C21H18F3N5	397.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC=CC(=C4)C(F)(F)F)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BO69MR	4-Dimethylamino-but-2-enoic acid [4-(3-bromo-phenylamino)-3-cyano-7-methoxy-quinolin-6-yl]-amide	Investigative	10322889	C23H22BrN5O2	480.4	CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=C(C=N2)C#N)NC3=CC(=CC=C3)Br)OC	IC50 = 790132.64 nM	Non binder
T59328	Epidermal growth factor receptor	BOMZ50	2,4-Diaminofuro[2,3-d]pyrimidine, 12	Investigative	44246329	C19H24N4O2	340.4	CC(C)CC(CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 500000 nM	Non binder
T59328	Epidermal growth factor receptor	BP2LX8	5-[(1z)-2-(2-Methoxyphenyl)prop-1-En-1-Yl]furo[2,3-D]pyrimidine-2,4-Diamine	Investigative	11687971	C16H16N4O2	296.32	C/C(=C/C1=COC2=NC(=NC(=C12)N)N)/C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BP6RW4	N-(3-Bromophenyl)-6-(2-methylbenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887074	C20H17BrN4	393.3	CC1=CC=CC=C1CC2=CC3=C(N2)N=CN=C3NC4=CC(=CC=C4)Br	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BPBM93	2-[(3-Fluoro-4-methoxyphenyl)methylidene]propanedinitrile	Investigative	5328747	C11H7FN2O	202.18	COC1=C(C=C(C=C1)C=C(C#N)C#N)F	IC50 = 800000 nM	Non binder
T59328	Epidermal growth factor receptor	BPHX43	4-N-(4-Chlorophenyl)-6-[(2,5-dimethoxyphenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57392425	C21H20ClN5O2	409.9	COC1=CC(=C(C=C1)OC)CC2=CC3=C(N2)N=C(N=C3NC4=CC=C(C=C4)Cl)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BPL8M1	2-Amino-4-(m-bromoanilino)-6-(2,5-dimethoxybenzyl)-7-methyl-pyrrolo[2,3-d]pyrimidine	Investigative	52947574	C22H22BrN5O2	468.3	CN1C(=CC2=C(N=C(N=C21)N)NC3=CC(=CC=C3)Br)CC4=C(C=CC(=C4)OC)OC	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BPLH59	4-N-(3-Bromophenyl)-7-[(3,4-dichlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57398331	C19H14BrCl2N5	463.2	C1=CC(=CC(=C1)Br)NC2=C3C=CN(C3=NC(=N2)N)CC4=CC(=C(C=C4)Cl)Cl	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BQ52YH	(3R,4S)-3-Fluoro-1-[4-[[2-[(1R)-1-hydroxyethyl]-1-[(2R)-1,1,1-trifluoropropan-2-yl]imidazo[4,5-c]pyridin-6-yl]amino]pyrimidin-2-yl]piperidin-4-ol	Investigative	90183658	C20H23F4N7O2	469.4	C[C@H](C1=NC2=CN=C(C=C2N1[C@H](C)C(F)(F)F)NC3=NC(=NC=C3)N4CC[C@@H]([C@@H](C4)F)O)O	IC50 = 261000 nM	Non binder
T59328	Epidermal growth factor receptor	BQ9DA6	2-(1H-Imidazol-2-ylmethylidene)propanedinitrile	Investigative	5328746	C7H4N4	144.13	C1=CN=C(N1)C=C(C#N)C#N	IC50 = 532000 nM	Non binder
T59328	Epidermal growth factor receptor	BQD2B9	N-(3-Chlorophenyl)-5,6,7-trimethylpyrrolo[2,3-d]pyrimidin-4-amine	Investigative	44346250	C15H15ClN4	286.76	CC1=C(N(C2=NC=NC(=C12)NC3=CC(=CC=C3)Cl)C)C	IC50 = 450000 nM	Non binder
T59328	Epidermal growth factor receptor	BQH90J	4-N-(3-Bromophenyl)-7-(naphthalen-1-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57394787	C23H18BrN5	444.3	C1=CC=C2C(=C1)C=CC=C2CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BQK7G2	13-Amino-5,21-dihydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	19037238	C26H22N4O9	534.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)N)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BRAZ27	Propanedinitrile, 2-[hydroxy(4-methoxyphenyl)methylene]-	Investigative	5328799	C11H8N2O2	200.19	COC1=CC=C(C=C1)C(=C(C#N)C#N)O	IC50 = 450000 nM	Non binder
T59328	Epidermal growth factor receptor	BS9O8R	2-{[4-(Methylsulfanyl)phenyl]methylidene}propanedinitrile	Investigative	710163	C11H8N2S	200.26	CSC1=CC=C(C=C1)C=C(C#N)C#N	IC50 > 625000 nM	Non binder
T59328	Epidermal growth factor receptor	BS9TZ1	N-[4-Fluoro-3-(trifluoromethyl)phenyl]-6-(2-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887348	C21H16F4N4	400.4	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=CN=C3NC4=CC(=C(C=C4)F)C(F)(F)F	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BSVN93	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]-4-methylbenzenesulfonamide	Investigative	44273699	C33H28N4O11S	688.7	CC1=CC=C(C=C1)S(=O)(=O)NN2C(=O)C3=C4C5=C(C(=CC=C5)O)NC4=C6C(=C3C2=O)C7=C(N6C8C(C(C(C(O8)CO)O)O)O)C(=CC=C7)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BTQ70E	5-[2-(2-Methoxyphenyl)-4-methylpent-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52946619	C19H22N4O2	338.4	CC(C)CC(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BTU79P	2-Amino-4-(m-bromoanilino)-6-benzyl-7-methyl-pyrrolo-[2,3-d]pyrimidine	Investigative	46912443	C20H18BrN5	408.3	CN1C(=CC2=C(N=C(N=C21)N)NC3=CC(=CC=C3)Br)CC4=CC=CC=C4	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BTZ87B	5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-(3-methoxyphenyl)-2-phenyl-3,4-dihydropyrazole	Investigative	127052875	C24H22N2O3	386.4	COC1=CC=CC(=C1)C2CC(=NN2C3=CC=CC=C3)C4=CC5=C(C=C4)OCCO5	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BU82EQ	N-[2-[(3R)-3-(Dimethylamino)pyrrolizino]-4-methoxy-5-[4-(pyrazolo[1,5-a]pyridine-3-yl)-5-chloropyrimidine-2-ylamino]phenyl]acrylamide	Investigative	86677234	C27H29ClN8O2	533	CN(C)[C@@H]1CCN(C1)C2=CC(=C(C=C2NC(=O)C=C)NC3=NC=C(C(=N3)C4=C5C=CC=CN5N=C4)Cl)OC	IC50 = 357000 nM	Non binder
T59328	Epidermal growth factor receptor	BUN83B	(2E)-2-Cyano-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid	Investigative	720879	C11H9NO4	219.19	COC1=C(C=CC(=C1)/C=C(\\C#N)/C(=O)O)O	IC50 = 325000 nM	Non binder
T59328	Epidermal growth factor receptor	BV4G0U	(3,5-Dimethoxybenzylidene)propanedinitrile	Investigative	282723	C12H10N2O2	214.22	COC1=CC(=CC(=C1)C=C(C#N)C#N)OC	Ki > 400000 nM	Non binder
T59328	Epidermal growth factor receptor	BV52IQ	US9422297, Aag145-340	Investigative	129625874	C17H13ClN4	308.8	C1C2=CC=CC=C2C3=C1C(=NC(=N3)N)NC4=CC=C(C=C4)Cl	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BV5ZU0	(E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenylamino)-3-cyano-quinolin-6-yl]-amide	Investigative	9954075	C22H19ClFN5O	423.9	CN(C)C/C=C/C(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=C(C=C3)F)Cl	IC50 = 650129.69 nM	Non binder
T59328	Epidermal growth factor receptor	BVE28X	2-Cyano-N-[5,21-dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]acetamide	Investigative	44273605	C29H23N5O10	601.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC(=O)CC#N)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BVG59H	5-[2-(2-Methoxyphenyl)hex-1-enyl]furo[2,3-d]pyrimidine-2,4-diamine	Investigative	52947801	C19H22N4O2	338.4	CCCCC(=CC1=COC2=NC(=NC(=C12)N)N)C3=CC=CC=C3OC	IC50 = 529300 nM	Non binder
T59328	Epidermal growth factor receptor	BW0I5K	2-(4-Formylphenyl)ethene-1,1,2-tricarbonitrile	Investigative	44576156	C12H5N3O	207.19	C1=CC(=CC=C1C=O)C(=C(C#N)C#N)C#N	IC50 = 600000 nM	Non binder
T59328	Epidermal growth factor receptor	BW1NE7	N4-(4-Bromo-2-chlorophenyl)-6-(2,4-dichlorobenzyl)-7Hpyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	46845026	C19H13BrCl3N5	497.6	C1=CC(=C(C=C1Cl)Cl)CC2=CC3=C(N2)N=C(N=C3NC4=C(C=C(C=C4)Br)Cl)N	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BW53EL	4-N-(3-Bromophenyl)-7-(naphthalen-2-ylmethyl)pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57396545	C23H18BrN5	444.3	C1=CC=C2C=C(C=CC2=C1)CN3C=CC4=C(N=C(N=C43)N)NC5=CC(=CC=C5)Br	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BWC63I	N-[4-(3-Bromoanilino)-3-cyanoquinolin-6-yl]-4-(2-methoxyethoxy)but-2-ynamide	Investigative	11005320	C23H19BrN4O3	479.3	COCCOCC#CC(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=CC=C3)Br	IC50 = 930036.51 nM	Non binder
T59328	Epidermal growth factor receptor	BWS68L	5-[(2,5-Dihydroxyphenyl)methylideneamino]-2-hydroxy-N-methoxybenzamide	Investigative	135474309	C15H14N2O5	302.28	CONC(=O)C1=C(C=CC(=C1)N=CC2=C(C=CC(=C2)O)O)O	IC50 ~ 100000 nM	Non binder
T59328	Epidermal growth factor receptor	BX70BH	N-[4-(3-Bromo-phenylamino)-3-cyano-quinolin-6-yl]-acrylamide	Investigative	9930439	C19H13BrN4O	393.2	C=CC(=O)NC1=CC2=C(C(=CN=C2C=C1)C#N)NC3=CC(=CC=C3)Br	IC50 = 590065.2 nM	Non binder
T59328	Epidermal growth factor receptor	BX9YG7	2-(4-Hydroxyphenyl)ethene-1,1,2-tricarbonitrile	Investigative	44576155	C11H5N3O	195.18	C1=CC(=CC=C1C(=C(C#N)C#N)C#N)O	IC50 = 600000 nM	Non binder
T59328	Epidermal growth factor receptor	BXR0Q7	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]-2-hydroxyacetamide	Investigative	44273624	C28H24N4O11	592.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC(=O)CO)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BXR9V1	4-[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-phenyl-3,4-dihydropyrazol-3-yl]-N,N-dimethylaniline	Investigative	127052874	C25H25N3O2	399.5	CN(C)C1=CC=C(C=C1)C2CC(=NN2C3=CC=CC=C3)C4=CC5=C(C=C4)OCCO5	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BYB8Q1	Benzylidenemalononitrile (BMN) deriv. 38	Investigative	5328795	C12H11NO4	233.22	C/C(=C(/C#N)\\C(=O)O)/C1=CC(=C(C=C1)O)OC	Ki = 341000 nM	Non binder
T59328	Epidermal growth factor receptor	BYD0N1	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]benzamide	Investigative	44273653	C33H26N4O10	638.6	C1=CC=C(C=C1)C(=O)NN2C(=O)C3=C4C5=C(C(=CC=C5)O)NC4=C6C(=C3C2=O)C7=C(N6C8C(C(C(C(O8)CO)O)O)O)C(=CC=C7)O	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BZ2AF9	N4-(3-Bromo-4-fluorophenyl)-6-phenethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	10251852	C20H17BrFN5	426.3	C1=CC=C(C=C1)CCC2=CC3=C(N2)N=C(N=C3NC4=CC(=C(C=C4)F)Br)N	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BZ57US	(E)-2-Cyano-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid	Investigative	5328790	C12H11NO5	249.22	COC1=CC(=CC(=C1O)OC)/C=C(\\C#N)/C(=O)O	IC50 = 264000 nM	Non binder
T59328	Epidermal growth factor receptor	BZ9X0H	4-N-(3-Bromophenyl)-7-[(2-chlorophenyl)methyl]pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	57384105	C19H15BrClN5	428.7	C1=CC=C(C(=C1)CN2C=CC3=C(N=C(N=C32)N)NC4=CC(=CC=C4)Br)Cl	IC50 > 200000 nM	Non binder
T59328	Epidermal growth factor receptor	BZFX31	US9422297, Aag145-346	Investigative	129625877	C17H13FN4	292.31	C1C2=CC=CC=C2C3=C1C(=NC(=N3)N)NC4=CC(=CC=C4)F	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	BZN1Q0	N-[4-(3-Bromo-phenylamino)-3-cyano-7-methoxy-quinolin-6-yl]-acrylamide	Investigative	10295839	C20H15BrN4O2	423.3	COC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=CC=C3)Br)C#N)NC(=O)C=C	IC50 = 810027.94 nM	Non binder
T59328	Epidermal growth factor receptor	BZW8Q7	N-(3-Bromophenyl)-6-(2,5-dimethoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	46887110	C21H19BrN4O2	439.3	COC1=CC(=C(C=C1)OC)CC2=CC3=C(N2)N=CN=C3NC4=CC(=CC=C4)Br	IC50 > 300000 nM	Non binder
T59328	Epidermal growth factor receptor	D0V9EN	3,4-Dihydroxycinnamic Acid	Investigative	689043	C9H8O4	180.16	C1=CC(=C(C=C1/C=C/C(=O)O)O)O	Ki = 400000 nM	Non binder