TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T60182 Glucagon receptor B2L6BC 3-[(1H-Benzimidazole-2-ylthio)acetyl]benzoic acid Investigative 10519171 C16H12N2O3S 312.3 C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC(=CC=C3)C(=O)O Ki > 500000 nM Non binder T60182 Glucagon receptor B38NPW 1-(3,4-Dihydroxyphenyl)-2-(1H-imidazole-2-ylthio)ethanone Investigative 10729333 C11H10N2O3S 250.28 C1=CC(=C(C=C1C(=O)CSC2=NC=CN2)O)O Ki > 500000 nM Non binder T60182 Glucagon receptor B5SPL2 2-(1H-Benzimidazol-2-ylsulfanyl)-1-(3,4-dimethoxyphenyl)ethanone Investigative 825433 C17H16N2O3S 328.4 COC1=C(C=C(C=C1)C(=O)CSC2=NC3=CC=CC=C3N2)OC Ki > 500000 nM Non binder T60182 Glucagon receptor B8GUF7 1-(3,4-Dihydroxyphenyl)-2-(benzoxazole-2-ylthio)ethanone Investigative 4450383 C15H11NO4S 301.3 C1=CC=C2C(=C1)N=C(O2)SCC(=O)C3=CC(=C(C=C3)O)O Ki = 250000 nM Non binder T60182 Glucagon receptor B8OW2I 4-[2-(1H-Benzoimidazol-2-ylsulfanyl)-1-hydroxy-ethyl]-2-chloro-phenol Investigative 10829563 C15H13ClN2O2S 320.8 C1=CC=C2C(=C1)NC(=N2)SCC(C3=CC(=C(C=C3)O)Cl)O Ki > 500000 nM Non binder T60182 Glucagon receptor B9OP7B 2-(1H-Benzoimidazol-2-ylsulfanyl)-1-(3-chloro-4-hydroxy-phenyl)-ethanone O-methyl-oxime Investigative 135503833 C16H14ClN3O2S 347.8 CO/N=C(/CSC1=NC2=CC=CC=C2N1)\\C3=CC(=C(C=C3)O)Cl Ki > 500000 nM Non binder T60182 Glucagon receptor BA72CY 1-(3-Hydroxyphenyl)-2-(1H-benzimidazole-2-ylthio)ethanone Investigative 10613052 C15H12N2O2S 284.3 C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC(=CC=C3)O Ki = 380000 nM Non binder T60182 Glucagon receptor BCKD18 1-(3,4-Dihydroxyphenyl)-4-(1H-benzimidazole-2-ylthio)-1-butanone Investigative 10640008 C17H16N2O3S 328.4 C1=CC=C2C(=C1)NC(=N2)SCCCC(=O)C3=CC(=C(C=C3)O)O Ki > 500000 nM Non binder T60182 Glucagon receptor BI8H5R 2-(1H-Benzimidazol-2-ylsulfanyl)-1-phenylethanone Investigative 416615 C15H12N2OS 268.3 C1=CC=C(C=C1)C(=O)CSC2=NC3=CC=CC=C3N2 Ki > 500000 nM Non binder T60182 Glucagon receptor BMWE02 1-(3,4-Dichlorophenyl)-2-(1H-benzimidazole-2-ylthio)ethanone Investigative 747420 C15H10Cl2N2OS 337.2 C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC(=C(C=C3)Cl)Cl Ki > 500000 nM Non binder T60182 Glucagon receptor BN24OF 1-(3,4-Dihydroxyphenyl)-2-(1-methyl-1H-benzimidazole-2-ylthio)ethanone Investigative 10638990 C16H14N2O3S 314.4 CN1C2=CC=CC=C2N=C1SCC(=O)C3=CC(=C(C=C3)O)O Ki > 500000 nM Non binder T60182 Glucagon receptor BO0D5W 4-[(1H-Benzimidazole-2-ylthio)acetyl]benzoic acid Investigative 10757473 C16H12N2O3S 312.3 C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC=C(C=C3)C(=O)O Ki > 500000 nM Non binder T60182 Glucagon receptor BOL8G6 2-(1H-Benzimidazol-2-ylsulfanyl)-1-(3,5-dihydroxyphenyl)ethanone Investigative 71456188 C15H12N2O3S 300.3 C1=CC=C2C(=C1)NC(=N2)SCC(=O)C3=CC(=CC(=C3)O)O Ki > 500000 nM Non binder T60182 Glucagon receptor BS08ZM 2-(1H-Benzoimidazol-2-ylsulfanyl)-1-(3-chloro-4-hydroxy-phenyl)-ethanone O-benzyl-oxime Investigative 135503932 C22H18ClN3O2S 423.9 C1=CC=C(C=C1)CO/N=C(/CSC2=NC3=CC=CC=C3N2)\\C4=CC(=C(C=C4)O)Cl Ki > 500000 nM Non binder T60182 Glucagon receptor BV4L3Q 1-(3,4-Dihydroxyphenyl)-2-(1H-benzimidazol-2-ylthio)-1-pentanone Investigative 10854791 C18H18N2O3S 342.4 CCCC(C(=O)C1=CC(=C(C=C1)O)O)SC2=NC3=CC=CC=C3N2 Ki > 500000 nM Non binder