TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T61484	Chymotrypsin C	B08IVX	3-(4-Hydroxy-benzyl)-5-trifluoromethyl-pyran-2-one	Investigative	13660350	C13H9F3O3	270.2	C1=CC(=CC=C1CC2=CC(=COC2=O)C(F)(F)F)O	Ki = 1610000 nM	Non binder
T61484	Chymotrypsin C	B0IK7T	2-Chloro-benzenesulfonic acid 3-(3-guanidino-propoxy)-5-methyl-phenyl ester	Investigative	44287937	C17H20ClN3O4S	397.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCCCN=C(N)N	Ki > 200000 nM	Non binder
T61484	Chymotrypsin C	B19XPJ	4-Hydroxy-6-methyl-2-pyrone	Investigative	54675757	C6H6O3	126.11	CC1=CC(=CC(=O)O1)O	Ki = 6309573.44 nM	Non binder
T61484	Chymotrypsin C	B1UMR9	{2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,2-dihydro-pyridin-3-yl}-carbamic acid benzyl ester	Investigative	10004044	C21H22F3N3O5	453.4	CC(C)C(C(=O)C(F)(F)F)NC(=O)CN1C=CC=C(C1=O)NC(=O)OCC2=CC=CC=C2	Ki = 330000 nM	Non binder
T61484	Chymotrypsinogen B	B20PRC	(S)-3-Acetylamino-2-fluoro-4-phenyl-butyric acid methyl ester	Investigative	44298715	C13H16FNO3	253.27	CC(=O)N[C@@H](CC1=CC=CC=C1)C(C(=O)OC)F	Ki = 6440000 nM	Non binder
T61484	Chymotrypsin C	B2FL3D	2-Chlorobenzenesulfonic acid 3-methyl-5-(1-amidinopiperidine-4-ylmethoxy)phenyl ester	Investigative	9910982	C20H24ClN3O4S	437.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCC3CCN(CC3)C(=N)N	Ki > 200000 nM	Non binder
T61484	Chymotrypsin C	B3KSE4	4-Hydroxy-3,6-dimethyl-2H-pyran-2-one	Investigative	54690337	C7H8O3	140.14	CC1=CC(=C(C(=O)O1)C)O	Ki = 3467368.5 nM	Non binder
T61484	Chymotrypsin C	B46AZD	3-Naphthalen-1-ylmethyl-pyran-2-one	Investigative	13615458	C16H12O2	236.26	C1=CC=C2C(=C1)C=CC=C2CC3=CC=COC3=O	Ki = 324000 nM	Non binder
T61484	Chymotrypsin C	B4GKT8	3-Ethyl-6-chloro-2-pyranone	Investigative	13615444	C7H7ClO2	158.58	CCC1=CC=C(OC1=O)Cl	Ki = 785000 nM	Non binder
T61484	Chymotrypsinogen B	B4ZFI3	N-((S)-1-Mercaptomethyl-2-phenyl-ethyl)-acetamide	Investigative	16723297	C11H15NOS	209.31	CC(=O)N[C@@H](CC1=CC=CC=C1)CS	IC50 > 800000 nM	Non binder
T61484	Chymotrypsin C	B5HEC6	3-n-Butyl-6-chloro-2-pyranone	Investigative	13615449	C9H11ClO2	186.63	CCCCC1=CC=C(OC1=O)Cl	Ki = 1980000 nM	Non binder
T61484	Chymotrypsin C	B64JTF	[3,5-Dibutyl-2-(3-methyloxiran-2-yl)-6-oxopyran-4-yl] acetate	Investigative	23276169	C18H26O5	322.4	CCCCC1=C(OC(=O)C(=C1OC(=O)C)CCCC)C2C(O2)C	Ki = 501187.23 nM	Non binder
T61484	Chymotrypsin C	B6EYW8	N-{2-[(2-Acetylamino-propionyl)-hydrazono]-ethyl}-benzamide	Investigative	14542109	C14H18N4O3	290.32	C[C@@H](C(=O)N/N=C/CNC(=O)C1=CC=CC=C1)NC(=O)C	Ki > 8000000 nM	Non binder
T61484	Chymotrypsin C	B6JAR4	3,5-Dibutyl-4-hydroxy-6-[(E)-1-phenylprop-1-enyl]pyran-2-one	Investigative	54733674	C22H28O3	340.5	CCCCC1=C(C(=C(OC1=O)/C(=C/C)/C2=CC=CC=C2)CCCC)O	Ki = 323593.66 nM	Non binder
T61484	Chymotrypsin C	B7R3JX	3,5-Dibutyl-4-hydroxy-6-(2-oxopropyl)pyran-2-one	Investigative	54694053	C16H24O4	280.36	CCCCC1=C(OC(=O)C(=C1O)CCCC)CC(=O)C	Ki = 8128305.16 nM	Non binder
T61484	Chymotrypsin C	B7VOI8	2-Thioxo-4-oxo-5-[(Z)-2-fluoro-5-nitrobenzylidene]thiazolidine-3-acetic acid	Investigative	6475892	C12H7FN2O5S2	342.3	C1=CC(=C(C=C1[N+](=O)[O-])/C=C\\2/C(=O)N(C(=S)S2)CC(=O)O)F	IC50 > 200000 nM	Non binder
T61484	Chymotrypsin C	B8A5NH	[3,5-Dibutyl-2-oxo-6-(2-oxopropyl)pyran-4-yl] acetate	Investigative	23276168	C18H26O5	322.4	CCCCC1=C(OC(=O)C(=C1OC(=O)C)CCCC)CC(=O)C	Ki = 660693.45 nM	Non binder
T61484	Chymotrypsinogen B	B8ENF0	Cbz-D-phenylalaninol	Investigative	736170	C17H19NO3	285.34	C1=CC=C(C=C1)C[C@H](CO)NC(=O)OCC2=CC=CC=C2	IC50 > 3000000 nM	Non binder
T61484	Chymotrypsin C	B8TOS5	N-[(2R)-3-(3-Aminopropylsulfanyl)-1-[4-(2-hydroxyethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3,3-dimethyl-2,4-dihydro-1H-quinoline-8-sulfonamide	Investigative	12047384	C24H40N4O4S2	512.7	CC1(CC2=C(C(=CC=C2)S(=O)(=O)N[C@@H](CSCCCN)C(=O)N3CCC(CC3)CCO)NC1)C	Ki = 384000 nM	Non binder
T61484	Chymotrypsin C	BA7HD9	4-Hydroxy-3-methyl-6-phenacylpyran-2-one	Investigative	54733673	C14H12O4	244.24	CC1=C(C=C(OC1=O)CC(=O)C2=CC=CC=C2)O	Ki = 512861.38 nM	Non binder
T61484	Chymotrypsinogen B	BB12OY	Methyl 2-(3-benzamido-3-benzyl-2-oxoazetidin-1-yl)acetate	Investigative	10383359	C20H20N2O4	352.4	COC(=O)CN1CC(C1=O)(CC2=CC=CC=C2)NC(=O)C3=CC=CC=C3	Ki = 300000 nM	Non binder
T61484	Chymotrypsinogen B	BBZV19	N-((S)-1-Benzyl-2,2-difluoro-but-3-enyl)-acetamide	Investigative	44298765	C13H15F2NO	239.26	CC(=O)N[C@@H](CC1=CC=CC=C1)C(C=C)(F)F	Ki = 460000 nM	Non binder
T61484	Chymotrypsin C	BC3YZ5	Phenol, 4-[2-(3-bromophenyl)diazenyl]-	Investigative	135843141	C12H9BrN2O	277.12	C1=CC(=CC(=C1)Br)N=NC2=CC=C(C=C2)O	IC50 = 220000 nM	Non binder
T61484	Chymotrypsin C	BCN3P5	2H-Pyran-2-one, 6-chloro-4-phenyl-	Investigative	13615450	C11H7ClO2	206.62	C1=CC=C(C=C1)C2=CC(=O)OC(=C2)Cl	Ki = 382000 nM	Non binder
T61484	Chymotrypsin C	BET3R4	2H-Pyran-2-one, 5-(phenylmethyl)-	Investigative	44270798	C12H10O2	186.21	C1=CC=C(C=C1)CC2=COC(=O)C=C2	Ki = 295000 nM	Non binder
T61484	Chymotrypsin C	BF31UI	3-Benzyl-5-bromo-2-pyranone	Investigative	13660353	C12H9BrO2	265.1	C1=CC=C(C=C1)CC2=CC(=COC2=O)Br	Ki = 687000 nM	Non binder
T61484	Chymotrypsin C	BGMP70	3-Fluoren-9-ylidenemethyl-piperidine	Investigative	20778639	C19H19N	261.399	C1CC(CNC1)C=C2C3=CC=CC=C3C4=CC=CC=C42	IC50 = 700000 nM	Non binder
T61484	Chymotrypsin C	BGQS24	3-Benzyl-5-chloromethyl-pyran-2-one	Investigative	13660339	C13H11ClO2	234.68	C1=CC=C(C=C1)CC2=CC(=COC2=O)CCl	Ki = 412000 nM	Non binder
T61484	Chymotrypsinogen B	BH8L9O	1-Benzoyl-pyrrolidine-2-carboxylic acid ((S)-1-(R)-oxiranyl-2-phenyl-ethyl)-amide	Investigative	44328511	C22H24N2O3	364.4	C1CC(N(C1)C(=O)C2=CC=CC=C2)C(=O)N[C@@H](CC3=CC=CC=C3)[C@@H]4CO4	Ki = 820000 nM	Non binder
T61484	Chymotrypsin C	BI6SW3	3,5-Dibutyl-4-hydroxy-6-methylpyran-2-one	Investigative	54694049	C14H22O3	238.32	CCCCC1=C(OC(=O)C(=C1O)CCCC)C	Ki = 1348962.88 nM	Non binder
T61484	Chymotrypsinogen B	BJL3Q4	Z-L-Phenylalaninol	Investigative	853481	C17H19NO3	285.34	C1=CC=C(C=C1)C[C@@H](CO)NC(=O)OCC2=CC=CC=C2	IC50 > 3000000 nM	Non binder
T61484	Chymotrypsin C	BKV5P9	4-Hydroxy-3,5-dimethyl-6-phenacylpyran-2-one	Investigative	54694052	C15H14O4	258.269	CC1=C(OC(=O)C(=C1O)C)CC(=O)C2=CC=CC=C2	Ki = 691830.97 nM	Non binder
T61484	Chymotrypsin C	BL5MH9	4-Hydroxy-3,5,6-trimethyl-2H-pyran-2-one	Investigative	54694046	C8H10O3	154.16	CC1=C(OC(=O)C(=C1O)C)C	Ki = 1819700.86 nM	Non binder
T61484	Chymotrypsin C	BL6P4C	3-Benzyl-6-trifluoromethyl-pyran-2-one	Investigative	13615457	C13H9F3O2	254.2	C1=CC=C(C=C1)CC2=CC=C(OC2=O)C(F)(F)F	Ki = 927000 nM	Non binder
T61484	Chymotrypsin C	BLX42T	2H-Pyran-2-one, 4-phenyl-	Investigative	12207594	C11H8O2	172.18	C1=CC=C(C=C1)C2=CC(=O)OC=C2	Ki = 495000 nM	Non binder
T61484	Chymotrypsinogen B	BMU43W	Tert-butyl 2,3-dioxoindole-1-carboxylate	Investigative	10060517	C13H13NO4	247.25	CC(C)(C)OC(=O)N1C2=CC=CC=C2C(=O)C1=O	Ki > 2000000 nM	Non binder
T61484	Chymotrypsin C	BP1C5O	3-Naphthalen-2-ylmethyl-pyran-2-one	Investigative	13615451	C16H12O2	236.26	C1=CC=C2C=C(C=CC2=C1)CC3=CC=COC3=O	Ki = 267000 nM	Non binder
T61484	Chymotrypsin C	BQ2U9E	4-Hydroxy-6-(2-oxo-2-phenylethyl)-2H-pyran-2-one	Investigative	54694048	C13H10O4	230.22	C1=CC=C(C=C1)C(=O)CC2=CC(=CC(=O)O2)O	Ki = 549540.87 nM	Non binder
T61484	Chymotrypsinogen B	BQ9L6R	(S)-2-{[(2S,4R)-1-((S)-2-{(S)-2-[(R)-2-((S)-2-Acetylamino-3-carboxy-propionylamino)-4-carboxy-butyrylamino]-2-cyclohexyl-acetylamino}-3-methyl-butyryl)-4-(naphthalen-2-ylmethoxy)-pyrrolidine-2-carbonyl]-amino}-pentanoic acid	Investigative	481437	C45H62N6O13	895	CCC[C@@H](C(=O)O)NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@H](C(C)C)NC(=O)[C@H](C2CCCCC2)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)C)OCC3=CC4=CC=CC=C4C=C3	IC50 > 300000 nM	Non binder
T61484	Chymotrypsin C	BT9OX7	[3,5-Dibutyl-2-(2-hydroxypropyl)-6-oxopyran-4-yl] acetate	Investigative	23276182	C18H28O5	324.4	CCCCC1=C(OC(=O)C(=C1OC(=O)C)CCCC)CC(C)O	Ki = 707945.78 nM	Non binder
T61484	Chymotrypsin C	BV9O7Y	3-(4-Methoxy-benzyl)-5-trifluoromethyl-pyran-2-one	Investigative	13660349	C14H11F3O3	284.23	COC1=CC=C(C=C1)CC2=CC(=COC2=O)C(F)(F)F	Ki = 893000 nM	Non binder
T61484	Chymotrypsin C	BWA3N8	Elasnin	Investigative	54685126	C24H40O4	392.6	CCCCCC(=O)C(CCCC)C1=C(C(=C(C(=O)O1)CCCC)O)CCCC	Ki = 223872.11 nM	Non binder
T61484	Chymotrypsin C	BZ1E6L	6-Chloro-3-naphthalen-2-ylmethyl-pyran-2-one	Investigative	13615446	C16H11ClO2	270.71	C1=CC=C2C=C(C=CC2=C1)CC3=CC=C(OC3=O)Cl	Ki = 625000 nM	Non binder
T61484	Chymotrypsin C	BZ2RS8	3-Benzyl-5-trifluoromethyl-pyran-2-one	Investigative	13660348	C13H9F3O2	254.2	C1=CC=C(C=C1)CC2=CC(=COC2=O)C(F)(F)F	Ki = 470000 nM	Non binder