TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T62431	Tyrosine-protein kinase SYK	B06KZV	1,2,4-Oxadiazole Analogue 12b	Investigative	5329220	C22H23Cl2N4O8P	573.3	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC(=C(C=C3)Cl)Cl	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B0CWL3	(3S)-3-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid	Investigative	44353828	C26H40N5O11P	629.6	CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C	IC50 = 389000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B0NU2W	1,2,4-Oxadiazole Analogue 14d	Investigative	6326462	C30H30F3N4O8P	662.5	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)CC4=CC=C(C=C4)OC	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B0SOP5	1,2,4-Oxadiazole Analogue 5n	Investigative	5329197	C22H23BrIN4O7P	693.2	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)I)Br)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B1AK9I	N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,4]oxadiazol-5-yl]-ethyl}-3-(4-phosphonooxy-benzyl)-succinamic acid	Investigative	10347718	C22H22Cl2N3O8P	558.3	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)Cl)Cl)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)CC(=O)O	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B1D7YN	1,2,4-Oxadiazole Analogue 5b	Investigative	6326455	C22H24ClN4O7P	522.9	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)Cl)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B1DV8M	1,2,4-Oxadiazole Analogue 14f	Investigative	6326463	C31H29F3N5O7P	671.6	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)CC4=CNC5=CC=CC=C54	IC50 = 433000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B2BI5Q	1,2,4-Oxadiazole Analogue 4g	Investigative	5329183	C24H26Cl2N5O8P	614.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=C(C=C(C=C3)Cl)Cl	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B2D8OP	1,2,4-Oxadiazole Analogue 4j	Investigative	5329216	C28H30N5O8P	595.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=CC4=CC=CC=C4C=C3	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B2X1KJ	1,2,4-Oxadiazole Analogue 5e	Investigative	5329218	C26H27N4O7P	538.5	C[C@@H](C1=NC(=NO1)CC2=CC3=CC=CC=C3C=C2)NC(=O)[C@H](CC4=CC=C(C=C4)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B2XAR6	1,2,4-Oxadiazole Analogue 4i	Investigative	5329185	C28H30N5O8P	595.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=CC=CC4=CC=CC=C43	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B2XPV7	N-{1-[3-(3,4-Dichloro-benzyl)-[1,2,4]oxadiazol-5-yl]-2-hydroxy-ethyl}-3-(4-phosphonooxy-benzyl)-succinamic acid	Investigative	10031003	C22H22Cl2N3O9P	574.3	C1=CC(=CC=C1C[C@H](CC(=O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC(=C(C=C3)Cl)Cl)OP(=O)(O)O	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B2Y7EI	1,2,4-Oxadiazole Analogue 5m	Investigative	5329196	C22H23ClIN4O7P	648.8	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)I)Cl)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 = 464000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B35JFN	(4R)-4-[(1R)-1-(1,6-Naphthyridin-5-yloxy)ethyl]pyrrolidin-2-one	Investigative	58072094	C14H15N3O2	257.29	C[C@H]([C@@H]1CC(=O)NC1)OC2=NC=CC3=C2C=CC=N3	IC50 = 2156000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B3D0NL	(6Ar,10aS)-4-Methoxy-7,9-dimethyl-4,6,6a,7,8,10a-hexahydro-indolo[4,3-fg]quinoline	Investigative	10084407	C17H20N2O	268.35	CC1=C[C@@H]2[C@@H](CC3=CN(C4=CC=CC2=C34)OC)N(C1)C	IC50 = 285000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B3JBT1	1,2,4-Oxadiazole Analogue 5d	Investigative	5329217	C22H23Cl2N4O7P	557.3	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)Cl)Cl)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B3PL5E	1,2,4-Oxadiazole Analogue 11	Investigative	5329203	C24H26F3N4O7P	570.5	CC[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B4C3EF	1,2,4-Oxadiazole Analogue 5j	Investigative	6326459	C22H24IN4O7P	614.3	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)I)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 = 472000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B4F6AY	[4-[(2S)-2-Acetamido-3-[[(1S)-4-amino-4-oxo-1-[3-[(4,6,6-trimethylcyclohexa-2,4-dien-1-yl)methyl]-1,2,4-oxadiazol-5-yl]butyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	Investigative	44353827	C27H36N5O8P	589.6	CC1=CC(C(C=C1)CC2=NOC(=N2)[C@H](CCC(=O)N)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C)(C)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B4LW1S	Ac-pTyr-Glu-Thr-Leu-NH(2)	Investigative	56664830	C26H40N5O12P	645.6	C[C@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C)O	IC50 = 570000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B4R7YN	1,2,4-Oxadiazole Analogue 4c	Investigative	5329180	C27H34N5O8P	587.6	CC(C)C1=CC=C(C=C1)CC2=NOC(=N2)[C@H](CCC(=O)N)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B5A0FP	1,2,4-Oxadiazole Analogue 5a	Investigative	6326454	C23H27N4O7P	502.5	CC1=CC=C(C=C1)CC2=NOC(=N2)[C@H](C)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B5BMZ3	6-(2-Phenyl-ethenesulfonylamino)-hexanoic acid	Investigative	2063494	C14H19NO4S	297.37	C1=CC=C(C=C1)/C=C/S(=O)(=O)NCCCCCC(=O)O	IC50 = 8000000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B5UQ8E	1,2,4-Oxadiazole Analogue 15b	Investigative	5329227	C28H27Cl2N4O8P	649.4	C1=CC=C(C=C1)CC(=O)N[C@@H](CC2=CC=C(C=C2)OP(=O)(O)O)C(=O)N[C@@H](CO)C3=NC(=NO3)CC4=CC(=C(C=C4)Cl)Cl	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B62LBZ	1,2,4-Oxadiazole Analogue 5g	Investigative	5329189	C23H24F3N4O7P	556.4	C[C@@H](C1=NC(=NO1)CC2=CC(=CC=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B6RHC4	1,2,4-Oxadiazole Analogue 14c	Investigative	6326461	C29H26F5N4O7P	668.5	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)CC4=CC(=C(C=C4)F)F	IC50 = 397000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B6XD1U	1,2,4-Oxadiazole Analogue 4k	Investigative	5329186	C25H30N5O8P	559.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CCC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B7GT4L	N-[(S)-1-[3-(3,4-Dichlorobenzyl)-1,2,4-oxadiazole-5-yl]ethyl]-4-(phosphonooxy)benzenepropanamide	Investigative	12968819	C20H20Cl2N3O6P	500.3	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)Cl)Cl)NC(=O)CCC3=CC=C(C=C3)OP(=O)(O)O	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B7IFH6	[5-[[(1S)-1-[3-[(3,4-Dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]carbamoylamino]naphthalen-2-yl] dihydrogen phosphate	Investigative	44332978	C22H19Cl2N4O6P	537.3	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)Cl)Cl)NC(=O)NC3=CC=CC4=C3C=CC(=C4)OP(=O)(O)O	IC50 = 310000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B85KAN	1,2,4-Oxadiazole Analogue 15a	Investigative	5329226	C29H28F3N4O8P	648.5	C1=CC=C(C=C1)CC(=O)N[C@@H](CC2=CC=C(C=C2)OP(=O)(O)O)C(=O)N[C@@H](CO)C3=NC(=NO3)CC4=CC=C(C=C4)C(F)(F)F	IC50 = 318000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B8AS5O	1,2,4-Oxadiazole Analogue 14a	Investigative	6326460	C29H28F3N4O7P	632.5	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)CC4=CC=CC=C4	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B8QY4O	1,2,4-Oxadiazole Analogue 4b	Investigative	5329179	C25H30N5O8P	559.5	CC1=CC=C(C=C1)CC2=NOC(=N2)[C@H](CCC(=O)N)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B8SEN1	{4-Amino-2-[(4-ethoxyphenyl)amino]-1,3-thiazol-5-yl}(3-methoxyphenyl)methanone	Investigative	1301845	C19H19N3O3S	369.4	CCOC1=CC=C(C=C1)NC2=NC(=C(S2)C(=O)C3=CC(=CC=C3)OC)N	IC50 > 200000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B9V1MX	1,2,4-Oxadiazole Analogue 12f	Investigative	5329206	C22H24BrN4O8P	583.3	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC=C(C=C3)Br	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	B9VIC5	[2-[[(1S)-1-[3-[(3,4-Dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl]ethyl]carbamoyl]-1H-indol-5-yl] dihydrogen phosphate	Investigative	100942265	C20H17Cl2N4O6P	511.2	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)Cl)Cl)NC(=O)C3=CC4=C(N3)C=CC(=C4)OP(=O)(O)O	IC50 = 434000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BA3M0Y	1,2,4-Oxadiazole Analogue 14b	Investigative	5329209	C27H26F3N4O7PS	638.6	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)CC4=CC=CS4	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BAO8T5	1,2,4-Oxadiazole Analogue 5k	Investigative	5329194	C22H23Br2N4O7P	646.2	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)Br)Br)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BAR27X	3-(4-Phosphonooxy-benzyl)-N-{1-[3-(4-trifluoromethyl-benzyl)-[1,2,4]oxadiazol-5-yl]-ethyl}-succinamic acid	Investigative	9985193	C23H23F3N3O8P	557.4	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)CC(=O)O	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BAZK09	1,2,4-Oxadiazole Analogue 12d	Investigative	5329222	C23H24F3N4O8P	572.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC=C(C=C3)C(F)(F)F	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BB2PT6	1,2,4-Oxadiazole Analogue 7	Investigative	5329199	C22H22F3N4O7P	542.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)NCC2=NC(=NO2)CC3=CC=C(C=C3)C(F)(F)F	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BB72VM	1,2,4-Oxadiazole Analogue 13c	Investigative	5329225	C29H29Cl2N4O7P	647.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC2=CC=CC=C2)C3=NC(=NO3)CC4=CC(=C(C=C4)Cl)Cl	IC50 = 250000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BCU0E2	1,2,4-Oxadiazole Analogue 8	Investigative	5329200	C23H24F3N4O7P	556.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)NCCC2=NC(=NO2)CC3=CC=C(C=C3)C(F)(F)F	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BDA7S1	1,2,4-Oxadiazole Analogue 4e	Investigative	5329182	C24H27ClN5O8P	579.9	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=CC(=CC=C3)Cl	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BDE36L	1,2,4-Oxadiazole Analogue 10	Investigative	5329202	C31H29F3N5O7P	671.6	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C4=NC(=NO4)CC5=CC=C(C=C5)C(F)(F)F	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BDR18F	1,2,4-Oxadiazole Analogue 5i	Investigative	6326457	C22H24BrN4O7P	567.3	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)Br)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BE3V4O	1,2,4-Oxadiazole Analogue 4d	Investigative	5329181	C24H27ClN5O8P	579.9	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=CC=C(C=C3)Cl	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BE9I2P	1,2,4-Oxadiazole Analogue 5l	Investigative	5329195	C22H23BrClN4O7P	601.8	C[C@@H](C1=NC(=NO1)CC2=CC(=C(C=C2)Cl)Br)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BEYR24	1,2,4-Oxadiazole Analogue 12e	Investigative	5329205	C22H24FN4O8P	522.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC=C(C=C3)F	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BH8JE9	[4-[(2S)-2-(Tert-butylsulfonylmethyl)-3-oxo-3-[[(1S)-1-[3-[[4-(trifluoromethyl)phenyl]methyl]-1,2,4-oxadiazol-5-yl]ethyl]amino]propyl]phenyl] dihydrogen phosphate	Investigative	12968822	C26H31F3N3O8PS	633.6	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)CS(=O)(=O)C(C)(C)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BJ3X7A	1,2,4-Oxadiazole Analogue 5h	Investigative	6326456	C22H24FN4O7P	506.4	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BJH84B	1,2,4-Oxadiazole Analogue 12c	Investigative	5329221	C26H27N4O8P	554.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC4=CC=CC=C4C=C3	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BJQ64G	1,2,4-Oxadiazole Analogue 12a	Investigative	5329204	C22H24ClN4O8P	538.9	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC=C(C=C3)Cl	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BKLI45	1,2,4-Oxadiazole Analogue 12g	Investigative	5329207	C22H24IN4O8P	630.3	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CO)C2=NC(=NO2)CC3=CC=C(C=C3)I	IC50 = 452000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BMQ34D	2-(4-{4-[2-(5-Carboxy-pentylsulfamoyl)-vinyl]-phenylcarbamoyl}-cyclohexyl)-malonic acid	Investigative	11016822	C24H32N2O9S	524.6	C1CC(CCC1C(C(=O)O)C(=O)O)C(=O)NC2=CC=C(C=C2)/C=C/S(=O)(=O)NCCCCCC(=O)O	IC50 = 350000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BPCI51	1,2,4-Oxadiazole Analogue 13b	Investigative	5329224	C33H33N4O7P	628.6	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC2=CC=CC=C2)C3=NC(=NO3)CC4=CC5=CC=CC=C5C=C4	IC50 = 288000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BQJ5M6	1,2,4-Oxadiazole Analogue 5c	Investigative	6326458	C22H24ClN4O7P	522.9	C[C@@H](C1=NC(=NO1)CC2=CC(=CC=C2)Cl)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BR29LT	1,2,4-Oxadiazole Analogue 6	Investigative	5329198	C24H26F3N4O7P	570.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)NC(C)(C)C2=NC(=NO2)CC3=CC=C(C=C3)C(F)(F)F	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BS70HI	1,2,4-Oxadiazole Analogue 4f	Investigative	5329215	C24H26Cl2N5O8P	614.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=CC(=C(C=C3)Cl)Cl	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BS7H0M	1,2,4-Oxadiazole Analogue 14e	Investigative	5329212	C33H30F3N4O7P	682.6	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)CC4=CC5=CC=CC=C5C=C4	IC50 = 302000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BSE2B9	1,2,4-Oxadiazole Analogue 13a	Investigative	5329223	C30H30F3N4O7P	646.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC2=CC=CC=C2)C3=NC(=NO3)CC4=CC=C(C=C4)C(F)(F)F	IC50 = 323000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BU2BF3	Cyclohexanemalonic acid	Investigative	348911	C9H14O4	186.2	C1CCC(CC1)C(C(=O)O)C(=O)O	IC50 = 5900000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BV8O6Y	4-Cyclooctenylmalonic acid	Investigative	44362038	C11H16O4	212.24	C1C/C=C\\CCC(C1)C(C(=O)O)C(=O)O	IC50 = 7700000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BW24GD	1,2,4-Oxadiazole Analogue 9	Investigative	5329201	C24H25F3N5O8P	599.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CC(=O)N)C2=NC(=NO2)CC3=CC=C(C=C3)C(F)(F)F	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BW5Z8N	1,2,4-Oxadiazole Analogue 15c	Investigative	5329228	C32H31N4O8P	630.6	C1=CC=C(C=C1)CC(=O)N[C@@H](CC2=CC=C(C=C2)OP(=O)(O)O)C(=O)N[C@@H](CO)C3=NC(=NO3)CC4=CC5=CC=CC=C5C=C4	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BWVK17	(4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-amino-4-oxobutanoyl]amino]-5-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid	Investigative	44353815	C26H39N6O12P	658.6	CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C	IC50 = 420000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BX9V2P	1,2,4-Oxadiazole Analogue 5f	Investigative	6326464	C23H24F3N4O7P	556.4	C[C@@H](C1=NC(=NO1)CC2=CC=C(C=C2)C(F)(F)F)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	BY2EC5	1,2,4-Oxadiazole Analogue 4a	Investigative	5329214	C24H28N5O8P	545.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	D0NJ4H	MORIN	Investigative	5281670	C15H10O7	302.23	C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O	EC50 > 300000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	D0R7BX	RU78191	Investigative	75791	C9H8O4	180.16	C1=CC=C(C=C1)C(C(=O)O)C(=O)O	IC50 = 12000000 nM	Non binder
T62431	Tyrosine-protein kinase SYK	D0X7IM	1,3-DIPHENYLUREA	Investigative	7595	C13H12N2O	212.25	C1=CC=C(C=C1)NC(=O)NC2=CC=CC=C2	IC50 > 660000 nM	Non binder