TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T63505	Tyrosine-protein kinase ABL1	B6H8GM	6-Methyl-3-methylsulfanyl-1-(2,4,6-trichlorophenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-one	Investigative	135402910	C13H9Cl3N4OS	375.7	CC1=NC2=C(C(=O)N1)C(=NN2C3=C(C=C(C=C3Cl)Cl)Cl)SC	IC50 > 500000 nM	Non binder
T63505	Tyrosine-protein kinase ABL1	B7E5RS	8-(Trifluoromethyl)-7H-purin-6-amine	Investigative	3635406	C6H4F3N5	203.12	C1=NC(=C2C(=N1)N=C(N2)C(F)(F)F)N	IC50 = 380000 nM	Non binder
T63505	Tyrosine-protein kinase ABL1	B7JYB4	N-(5-Tert-butyl-1,3-thiazol-2-yl)-3-[(E)-2-[6-(cyclopropylamino)purin-9-yl]ethenyl]-4-methylbenzamide	Investigative	44222458	C25H27N7OS	473.6	CC1=C(C=C(C=C1)C(=O)NC2=NC=C(S2)C(C)(C)C)/C=C/N3C=NC4=C(N=CN=C43)NC5CC5	IC50 = 267000 nM	Non binder
T63505	Tyrosine-protein kinase ABL1	B7P4ZG	1-[2-(Furan-2-yl)pyrrolidin-1-yl]prop-2-en-1-one	Investigative	51346068	C11H13NO2	191.23	C=CC(=O)N1CCCC1C2=CC=CO2	Ki > 1250000 nM	Non binder
T63505	Tyrosine-protein kinase ABL1	B8PU2Q	(E)-N-(4-Methyl-3-(2-(6-(pyridine-2-yl-amino)-9H-purin-9-yl)vinyl)phenyl)-3-(trifluoromethyl)-benzamide	Investigative	44222109	C27H20F3N7O	515.5	CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)/C=C/N3C=NC4=C(N=CN=C43)NC5=CC=CC=N5	IC50 = 243000 nM	Non binder
T63505	Tyrosine-protein kinase ABL1	BGOV48	(E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(2-fluoro-5-(trifluoromethyl)phenyl)benzamide	Investigative	44221730	C25H20F4N6O	496.5	CC1=C(C=C(C=C1)C(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)/C=C/N3C=NC4=C(N=CN=C43)NC5CC5	IC50 = 236000 nM	Non binder
T63505	Tyrosine-protein kinase ABL1	BJ57YZ	N-(4-Methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine	Investigative	50908681	C19H16N2O2	304.3	COC1=CC=C(C=C1)CNC2=C3C4=CC=CC=C4OC3=NC=C2	IC50 = 392000 nM	Non binder
T63505	Tyrosine-protein kinase ABL1	BM5Y0Q	3-(4-Methoxyphenyl)-1H-indeno[1,2-c]pyrazol-4-one	Investigative	5092865	C17H12N2O2	276.29	COC1=CC=C(C=C1)C2=NNC3=C2C(=O)C4=CC=CC=C43	IC50 > 725000 nM	Non binder