TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T64553	Tyrosine-protein kinase ZAP-70	D06CIJ	ISIS-CRP	Phase 1	4878	C15H16ClN5	301.77	CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)Cl)N	IC50 > 100000000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B0CWL3	(3S)-3-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid	Investigative	44353828	C26H40N5O11P	629.6	CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C	IC50 = 328000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B1F0LD	(4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid	Investigative	44314380	C28H37N2O9P	576.6	CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)OCC(=O)O)P(=O)(O)O	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B4F6AY	[4-[(2S)-2-Acetamido-3-[[(1S)-4-amino-4-oxo-1-[3-[(4,6,6-trimethylcyclohexa-2,4-dien-1-yl)methyl]-1,2,4-oxadiazol-5-yl]butyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	Investigative	44353827	C27H36N5O8P	589.6	CC1=CC(C(C=C1)CC2=NOC(=N2)[C@H](CCC(=O)N)NC(=O)[C@H](CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C)(C)C	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B53GDR	[4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-(ethoxy-hydroxy-phosphoryl)-phenoxy]-acetic acid	Investigative	10100735	C31H42N3O10P	647.7	CCOP(=O)(C1=C(C=CC(=C1)CC(C(=O)N[C@@H](C)C2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N)NC(=O)C)OCC(=O)O)O	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B5FD4Y	(5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-hydroxy-phenyl)-phosphonic acid	Investigative	44314402	C26H35N2O7P	518.5	CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)O)P(=O)(O)O	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B5WQR4	(S)-4-{(S)-2-[(S)-2-Acetylamino-3-(4-phosphonooxy-phenyl)-propionylamino]-4-carboxy-butyrylamino}-4-((1S,2S)-1-carbamoyl-2-methyl-butylcarbamoyl)-butyric acid	Investigative	44315963	C27H40N5O13P	673.6	CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C	IC50 = 530000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B6SO8N	1-[(3-Methyl-1-{2-[(1,2,3-Trimethyl-1h-Indol-5-Yl)amino]pyrimidin-4-Yl}-1h-Pyrazol-4-Yl)methyl]azetidin-3-Ol	Investigative	71698379	C23H27N7O	417.5	CC1=C(N(C2=C1C=C(C=C2)NC3=NC=CC(=N3)N4C=C(C(=N4)C)CN5CC(C5)O)C)C	IC50 = 995800 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	B6XD1U	1,2,4-Oxadiazole Analogue 4k	Investigative	5329186	C25H30N5O8P	559.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CCC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BCU0E2	1,2,4-Oxadiazole Analogue 8	Investigative	5329200	C23H24F3N4O7P	556.4	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)NCCC2=NC(=NO2)CC3=CC=C(C=C3)C(F)(F)F	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BEYC70	[5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-(tetrazol-1-ylmethoxy)-phenyl]-phosphonic acid	Investigative	44313990	C28H37N6O7P	600.6	CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)OCN4C=NN=N4)P(=O)(O)O	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BI51XO	(4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid	Investigative	44313931	C30H40N3O10P	633.6	CC(=O)NC(CC1=CC(=C(C=C1)OCC(=O)O)P(=O)(O)O)C(=O)NC(C)(C)C2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BN14WA	{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-benzylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid	Investigative	44313930	C28H36N3O10P	605.6	CC(=O)NC(CC1=CC(=C(C=C1)OCC(=O)O)P(=O)(O)O)C(=O)NCC2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BR0A8S	Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenyl ester	Investigative	44313929	C27H34F3N2O9PS	650.6	CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)OS(=O)(=O)C(F)(F)F)P(=O)(O)O	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BR29LT	1,2,4-Oxadiazole Analogue 6	Investigative	5329198	C24H26F3N4O7P	570.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)NC(C)(C)C2=NC(=NO2)CC3=CC=C(C=C3)C(F)(F)F	IC50 = 228000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BWAR36	{4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-phenylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid	Investigative	44314373	C27H34N3O10P	591.5	CC(=O)NC(CC1=CC(=C(C=C1)OCC(=O)O)P(=O)(O)O)C(=O)NC2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BWVK17	(4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-amino-4-oxobutanoyl]amino]-5-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid	Investigative	44353815	C26H39N6O12P	658.6	CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C	IC50 = 422000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BX48FI	(4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid	Investigative	10461517	C29H38N3O10P	619.6	C[C@@H](C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)C(CC3=CC(=C(C=C3)OCC(=O)O)P(=O)(O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BY2EC5	1,2,4-Oxadiazole Analogue 4a	Investigative	5329214	C24H28N5O8P	545.5	CC(=O)N[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)C(=O)N[C@@H](CCC(=O)N)C2=NC(=NO2)CC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T64553	Tyrosine-protein kinase ZAP-70	BYLI28	[4-[2-Acetamido-3-[[(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl]amino]-3-oxopropyl]phenyl] dihydrogen phosphate	Investigative	44313997	C27H36N3O8P	561.6	C[C@@H](C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)OP(=O)(O)O)NC(=O)C	IC50 = 441000 nM	Non binder