TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T67619	RAC-alpha serine/threonine-protein kinase	B1QIP0	(2S)-2-[(2R)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-sulfanylpropanamido]-3-phenylpropanoic acid	Investigative	44440071	C41H66N14O12S	979.1	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)O	IC50 = 241000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B21CKL	4-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(2S)-1-[[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-3-phenylbenzamide	Investigative	44590349	C42H50N8O5	746.9	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC(=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)C)C4=CC=CC=C4	IC50 = 288000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B2UOH3	(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}-N-(4-{[(1S)-1-{[(1S)-1-{[3-(3-acetamidophenoxy)propyl]carbamoyl}-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}phenyl)pentanamide	Investigative	44440125	C53H75N15O10	1082.3	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCCOC2=CC=CC(=C2)NC(=O)C)NC(=O)C3=CC=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 322000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B30RTX	3-[6-Bromo-3-(4-tert-butylphenyl)imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine	Investigative	58345162	C21H20BrN5	422.3	CC(C)(C)C1=CC=C(C=C1)N2C3=C(C=C(C=N3)Br)N=C2C4=C(N=CC=C4)N	IC50 > 300000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B37BMG	Phenylaminoethyl guanidine deriv., 21bb	Investigative	44590353	C38H40N6O	596.8	CC1=CC=C(C=C1)CN(CC2=CC=C(C=C2)C)C3=CC=C(C=C3)NC(=O)C4=CC(=C(C=C4)NCCN=C(N)N)C5=CC=CC=C5	IC50 = 215000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B3X0ZT	7-Azaindole	Investigative	9222	C7H6N2	118.14	C1=CC2=C(NC=C2)N=C1	IC50 > 398107.17 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B49FVL	(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}-N-(4-{[(1S)-2-methyl-1-{[(1S)-2-phenyl-1-{[2-(piperidin-1-yl)ethyl]carbamoyl}ethyl]carbamoyl}propyl]carbamoyl}phenyl)pentanamide	Investigative	44440127	C49H75N15O8	1002.2	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCCN2CCCCC2)NC(=O)C3=CC=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 > 500000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B4I3RY	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]propanamido]-3-phenylpropanoic acid	Investigative	44440069	C41H66N14O12	947	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)O	IC50 = 409000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B6CR2N	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-(1H-imidazol-5-yl)propanamido]-3-phenylpropanoic acid	Investigative	44440056	C44H68N16O12	1013.1	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)O	IC50 > 500000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B7Z0NO	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-[2-(carboxyamino)acetamido]pentanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-carbamoylpropanamido]-3-phenylpropanoic acid	Investigative	44440091	C41H65N15O14	992	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)O)O	IC50 = 229000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	B9DNX1	Quinazolin-6-yl, 15b	Investigative	44590408	C37H38N8O5	674.7	CC(=O)N[C@@H](CCCN=C(N)N)C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC3=C(C=C2)N(C(=O)N(C3=O)CC4=CC=CC=C4)CC5=CC=CC=C5	IC50 = 232000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BA6EK0	3-(4-Tert-butylphenyl)-2-pyridin-4-ylimidazo[4,5-b]pyridine	Investigative	60155007	C21H20N4	328.4	CC(C)(C)C1=CC=C(C=C1)N2C3=C(C=CC=N3)N=C2C4=CC=NC=C4	IC50 > 300000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BE1LS0	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-methylbutanamido]-3-phenylpropanoic acid	Investigative	44440064	C43H70N14O12	975.1	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)O	IC50 = 445000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BE3Q6S	(2S)-N-[(1S,2R)-1-{[(1S,2R)-1-{[(1S)-1-{[(1S)-1-(Benzylcarbamoyl)-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-2-hydroxypropyl]-5-carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamide	Investigative	44440096	C50H77N15O11	1064.2	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)O	IC50 = 239000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BHVR75	6-Bromo-3-[(2-methoxyphenyl)methyl]-2-pyridin-4-ylimidazo[4,5-b]pyridine	Investigative	60155093	C19H15BrN4O	395.3	COC1=CC=CC=C1CN2C3=C(C=C(C=N3)Br)N=C2C4=CC=NC=C4	IC50 > 300000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BJ23ZR	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-phenylpropanamido]-3-phenylpropanoic acid	Investigative	44440046	C47H70N14O12	1023.1	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)O	IC50 > 500000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BJ5A7U	3-[3-(3-Tert-butylphenyl)imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine	Investigative	60155095	C21H21N5	343.4	CC(C)(C)C1=CC(=CC=C1)N2C3=C(C=CC=N3)N=C2C4=C(N=CC=C4)N	IC50 > 300000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BL3S9F	(2S)-N-[(1S)-1-(Benzylcarbamoyl)-2-phenylethyl]-2-({4-[(2S)-2-{[(2S)-1-[(2S)-2-(2-acetamidoacetamido)propanoyl]pyrrolidin-2-yl]formamido}propanamido]phenyl}formamido)-3-methylbutanamide	Investigative	44440139	C43H54N8O8	810.9	C[C@@H](C(=O)NC1=CC=C(C=C1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NCC3=CC=CC=C3)NC(=O)[C@@H]4CCCN4C(=O)[C@H](C)NC(=O)CNC(=O)C	IC50 > 500000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BN2Z1I	N-((S)-1-((S)-1-(Benzylamino)-1-oxo-3-phenylpropan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-4-(guanidinomethyl)benzamide	Investigative	44440158	C30H36N6O3	528.6	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)CN=C(N)N	IC50 > 500000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BP70CT	(2S)-1-[(2S)-2-[(2-Acetamidoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1-[4-[[(2S)-1-[[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamoyl]-2-phenylanilino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide	Investigative	44590346	C55H72N14O8	1057.2	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC(=C(C=C3)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)C5=CC=CC=C5	IC50 > 500000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BQD9Z7	3-[6-Bromo-3-[(2-methoxyphenyl)methyl]imidazo[4,5-b]pyridin-2-yl]pyridin-2-amine	Investigative	60155092	C19H16BrN5O	410.3	COC1=CC=CC=C1CN2C3=C(C=C(C=N3)Br)N=C2C4=C(N=CC=C4)N	IC50 > 300000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BT7JF9	1H-Indazole	Investigative	9221	C7H6N2	118.14	C1=CC=C2C(=C1)C=NN2	IC50 > 398107.17 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BTVA78	(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-5-Carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-(1H-indol-3-yl)propanamido]-3-phenylpropanoic acid	Investigative	44440036	C49H71N15O12	1062.2	C[C@H]([C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C)O	IC50 > 500000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BU6CP7	N-[(S)-1-((S)-1-Benzylcarbamoyl-2-phenyl-ethylcarbamoyl)-2-methyl-propyl]-4-(2-guanidino-ethylamino)-benzamide	Investigative	44440154	C31H39N7O3	557.7	CC(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=C(C=C3)NCCN=C(N)N	IC50 = 390000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BUB19L	(2S)-N-[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-(Benzylcarbamoyl)-2-phenylethyl]carbamoyl}-2-methylpropyl]carbamoyl}ethyl]carbamoyl}ethyl]-5-carbamimidamido-2-{[(2S)-1-[(2S)-5-carbamimidamido-2-(2-acetamidoacetamido)pentanoyl]pyrrolidin-2-yl]formamido}pentanamide	Investigative	44440098	C48H73N15O9	1004.2	C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC2=CC=CC=C2)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCN=C(N)N)NC(=O)CNC(=O)C	IC50 = 438000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BW4ME5	Phenylaminoethyl guanidine deriv., 22aa	Investigative	44590362	C38H39N7O2	625.8	CC(=O)NC1=CC=C(C=C1)C2=C(C=CC(=C2)C(=O)NC3=CC=C(C=C3)N(CC4=CC=CC=C4)CC5=CC=CC=C5)NCCN=C(N)N	IC50 = 253000 nM	Non binder
T67619	RAC-alpha serine/threonine-protein kinase	BYHV64	2-[4-(3-Phenylquinoxalin-2-yl)phenyl]propan-2-amine	Investigative	9819282	C23H21N3	339.4	CC(C)(C1=CC=C(C=C1)C2=NC3=CC=CC=C3N=C2C4=CC=CC=C4)N	IC50 > 250000 nM	Non binder