TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T68698	Adenosylhomocysteinase	D0H1OL	Guanosine	Phase 1	135398635	C10H13N5O5	283.24	.	Ki = 1472000 nM	Non binder
T68698	Adenosylhomocysteinase	B16EXS	(2,2-Dichlorocyclopropyl) 2-[(2R,3S,4R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]acetate	Investigative	46877256	C14H15Cl2N5O5	404.2	C1C(C1(Cl)Cl)OC(=O)C[C@@H]2[C@H]([C@H](C(O2)N3C=NC4=C(N=CN=C43)N)O)O	Ki = 750000 nM	Non binder
T68698	Adenosylhomocysteinase	B20NKB	5-(6-Aminopurin-9-yl)-4-iodocyclopent-3-ene-1,2-diol	Investigative	51003096	C10H10IN5O2	359.12	C1=C([C@H]([C@@H]([C@@H]1O)O)N2C=NC3=C(N=CN=C32)N)I	IC50 > 1000000 nM	Non binder
T68698	Adenosylhomocysteinase	B24IBK	5-(6-Aminopurin-9-yl)-4-iodo-3-hydroxymethylcyclopent-3-ene-1,2-diol	Investigative	53318848	C11H12IN5O3	389.15	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H](C(=C3I)CO)O)O)N	IC50 > 1000000 nM	Non binder
T68698	Adenosylhomocysteinase	B5O0FR	Inosine	Investigative	135398641	C10H12N4O5	268.23	C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O	Ki = 925000 nM	Non binder
T68698	Adenosylhomocysteinase	B5PEV2	5-(6-Aminopurin-9-yl)-4-bromocyclopent-3-ene-1,2-diol	Investigative	51003095	C10H10BrN5O2	312.12	C1=C([C@H]([C@@H]([C@@H]1O)O)N2C=NC3=C(N=CN=C32)N)Br	IC50 > 1000000 nM	Non binder
T68698	Adenosylhomocysteinase	BHU1R0	(2R,4As,5R,6S,8aS)-5-((2-chloro-5-methoxy-3,6-dioxocyclohexa-1,4-dienyl)methyl)-5,6,8a-trimethyl-1-methylenedecahydronaphthalen-2-yl 6-(tert-butoxycarbonylamino)hexanoate	Investigative	46886640	C33H48ClNO7	606.2	C[C@H]1CC[C@]2([C@H]([C@]1(C)CC3=C(C(=O)C=C(C3=O)OC)Cl)CC[C@H](C2=C)OC(=O)CCCCCNC(=O)OC(C)(C)C)C	IC50 > 250000 nM	Non binder
T68698	Adenosylhomocysteinase	BK3PV2	2-Amino-4-[3-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazol-4-yl]-1H-pyrimidin-6-one	Investigative	135976391	C12H15N5O5	309.28	C1=C(N=C(NC1=O)N)C2=CN=CN2C3[C@@H]([C@@H]([C@H](O3)CO)O)O	Ki = 217000 nM	Non binder
T68698	Adenosylhomocysteinase	BLC12J	4-[3-[(3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazol-4-yl]-1H-pyrimidin-6-one	Investigative	135976393	C12H14N4O5	294.26	C1=C(N=CNC1=O)C2=CN=CN2C3[C@@H]([C@@H]([C@H](O3)CO)O)O	Ki = 422000 nM	Non binder
T68698	Adenosylhomocysteinase	BTE18A	3alpha-(6-Amino-9H-purine-9-yl)-5beta-aminocyclopentane-1beta,2beta-diol	Investigative	44450579	C10H14N6O2	250.26	C1[C@H]([C@H]([C@H]([C@@H]1N2C=NC3=C(N=CN=C32)N)O)O)N	IC50 > 500000 nM	Non binder
T68698	Adenosylhomocysteinase	BX6R0G	5-(6-Aminopurin-9-yl)-4-chlorocyclopent-3-ene-1,2-diol	Investigative	51003094	C10H10ClN5O2	267.67	C1=C([C@H]([C@@H]([C@@H]1O)O)N2C=NC3=C(N=CN=C32)N)Cl	IC50 > 1000000 nM	Non binder