TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T71398 Guanylate cyclase B26CFM 1-[[2-(2-(4-Chlorophenyl)ethyl)-1,3-dioxolan-2-yl]methyl]imidazole hydrochloride Investigative 11659928 C15H18Cl2N2O2 329.2 C1COC(O1)(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3.Cl IC50 > 1000000 nM Non binder T71398 Guanylate cyclase B6FD5Q 1-[[(2S,4R)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride Investigative 11580958 C16H20Cl2N2O2 343.2 C[C@@H]1CO[C@](O1)(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3.Cl IC50 > 500000 nM Non binder T71398 Guanylate cyclase BRCS25 1-[[2-(2-(4-Chlorophenyl)ethyl)-1,3-dithiolan-2-yl]methyl]imidazole hydrochloride Investigative 11610203 C15H18Cl2N2S2 361.4 C1CSC(S1)(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3.Cl IC50 > 500000 nM Non binder T71398 Guanylate cyclase BV35GK 1-[[(2R,4R)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride Investigative 11624320 C16H20Cl2N2O2 343.2 C[C@@H]1CO[C@@](O1)(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3.Cl IC50 > 1000000 nM Non binder T71398 Guanylate cyclase BV3C7M 1-[[(2S,4S)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride Investigative 11595347 C16H20Cl2N2O2 343.2 C[C@H]1CO[C@](O1)(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3.Cl IC50 > 500000 nM Non binder T71398 Guanylate cyclase BWJY46 1-[[(2R,4S)-2-[2-(4-Chlorophenyl)ethyl]-4-methyl-1,3-dioxolan-2-yl]methyl]imidazole;hydrochloride Investigative 11681690 C16H20Cl2N2O2 343.2 C[C@H]1CO[C@@](O1)(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3.Cl IC50 > 500000 nM Non binder