TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T75440	Translocator protein	D0CP4E	Clonazepam	Approved	2802	C15H10ClN3O3	315.71	C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3Cl	IC50 = 555904257.3 nM	Non binder
T75440	Translocator protein	D0T5WK	Nitrazepam	Approved	4506	C15H11N3O3	281.27	C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3	IC50 = 100000000 nM	Non binder
T75440	Translocator protein	D0Z5OV	Delorazepam	Approved	17925	C15H10Cl2N2O	305.2	C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3Cl	IC50 = 555904257.3 nM	Non binder
T75440	Translocator protein	B0KY2Q	2H-1,4-Benzodiazepin-2-one, 5-(2-fluorophenyl)-1,3-dihydro-1,3-dimethyl-7-nitro-, (R)-	Investigative	128744	C17H14FN3O3	327.31	C[C@@H]1C(=O)N(C2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3F)C	IC50 = 142889395.9 nM	Non binder
T75440	Translocator protein	B1YK2X	7-Aminoflunitrazepam	Investigative	92294	C16H14FN3O	283.3	CN1C(=O)CN=C(C2=C1C=CC(=C2)N)C3=CC=CC=C3F	IC50 = 15381546.4 nM	Non binder
T75440	Translocator protein	B20ITA	7-Chloro-5-(2,6-difluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one	Investigative	23275763	C15H9ClF2N2O	306.69	C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=C(C=CC=C3F)F	IC50 = 625172692.8 nM	Non binder
T75440	Translocator protein	B29DJV	7-Fluoro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one	Investigative	44366179	C16H13FN2O	268.28	CN1C(=O)CN=C(C2=C1C=CC(=C2)F)C3=CC=CC=C3	IC50 = 58884365.54 nM	Non binder
T75440	Translocator protein	B2AUI1	7-Acetyl-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one	Investigative	23275854	C17H13FN2O2	296.29	CC(=O)C1=CC2=C(C=C1)NC(=O)CN=C2C3=CC=CC=C3F	IC50 = 55590425.73 nM	Non binder
T75440	Translocator protein	B2H0RU	2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-5-phenyl-7-(trifluoromethyl)-	Investigative	16795	C16H11F3N2O	304.27	C1C(=O)NC2=C(C=C(C=C2)C(F)(F)F)C(=N1)C3=CC=CC=C3	IC50 = 76913044.03 nM	Non binder
T75440	Translocator protein	B2QA6D	7-Chloro-5-(2,6-dichloro-phenyl)-1,3-dihydro-benzo[e][1,4]diazepin-2-one	Investigative	12790028	C15H9Cl3N2O	339.6	C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=C(C=CC=C3Cl)Cl	IC50 = 142889395.9 nM	Non binder
T75440	Translocator protein	B34QIB	Nordazepam	Investigative	2997	C15H11ClN2O	270.71	C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3	IC50 = 106414301.8 nM	Non binder
T75440	Translocator protein	B4BT9A	7-Chloro-5-(2,6-dichlorophenyl)-1-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one	Investigative	9975396	C16H11Cl3N2O	353.6	CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=C(C=CC=C3Cl)Cl	IC50 = 181970085.9 nM	Non binder
T75440	Translocator protein	B4FRB9	5-(2-Fluorophenyl)-8-methyl-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	44366169	C16H13FN2O	268.28	CC1=CC2=C(C=C1)C(=NCC(=O)N2)C3=CC=CC=C3F	IC50 = 52601726.64 nM	Non binder
T75440	Translocator protein	B51AQD	7-Chloro-5-(2,6-difluorophenyl)-1-methyl-1H-benzo[e][1,4]diazepin-2(3H)-one	Investigative	44366236	C16H11ClF2N2O	320.72	CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=C(C=CC=C3F)F	IC50 = 243781081.8 nM	Non binder
T75440	Translocator protein	B5E1BR	1-Tert-butyl-5-(2-fluorophenyl)-7-nitro-3H-1,4-benzodiazepin-2-one	Investigative	44366175	C19H18FN3O3	355.4	CC(C)(C)N1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F	IC50 = 3334264.13 nM	Non binder
T75440	Translocator protein	B5HKJ9	Norfludiazepam	Investigative	4540	C15H10ClFN2O	288.7	C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F	IC50 = 500034535 nM	Non binder
T75440	Translocator protein	B7JDZ5	2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-, (R)-	Investigative	44366192	C16H12ClN3O3	329.74	C[C@@H]1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3Cl	IC50 = 833681184.6 nM	Non binder
T75440	Translocator protein	B8MI5J	1-Methyl-5-(2-fluorophenyl)-7-fluoro-1,3-dihydro-2h-1,4-benzodiazepine-2-one	Investigative	23275675	C16H12F2N2O	286.28	CN1C(=O)CN=C(C2=C1C=CC(=C2)F)C3=CC=CC=C3F	IC50 = 195884467.4 nM	Non binder
T75440	Translocator protein	B8QZD3	7-Aminoclonazepam	Investigative	188298	C15H12ClN3O	285.73	C1C(=O)NC2=C(C=C(C=C2)N)C(=N1)C3=CC=CC=C3Cl	IC50 = 13335214.32 nM	Non binder
T75440	Translocator protein	B9MZJ2	2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-7-chloro-5-(2-fluorophenyl)-1-(2-hydroxyethyl)-	Investigative	30401	C17H14ClFN2O2	332.8	C1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CCO	IC50 = 40831938.63 nM	Non binder
T75440	Translocator protein	B9QVS2	Motrazepam	Investigative	65764	C17H15N3O4	325.32	COCN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3	IC50 = 2328091.26 nM	Non binder
T75440	Translocator protein	BA87WI	1H-1,4-Benzodiazepine-7-carbonitrile, 2,3-dihydro-1-methyl-2-oxo-5-phenyl-	Investigative	19011	C17H13N3O	275.3	CN1C(=O)CN=C(C2=C1C=CC(=C2)C#N)C3=CC=CC=C3	IC50 = 2630267.99 nM	Non binder
T75440	Translocator protein	BB6QI0	2H-1,4-Benzodiazepin-2-one, 7-chloro-1-(1,1-dimethylethyl)-1,3-dihydro-5-phenyl-	Investigative	622885	C19H19ClN2O	326.8	CC(C)(C)N1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3	IC50 = 1614358.56 nM	Non binder
T75440	Translocator protein	BBF06L	5-(2-Fluorophenyl)-7-iodo-1-methyl-1,3-dihydro-2h-1,4-benzodiazepin-2-one	Investigative	118749	C16H12FIN2O	394.18	CN1C(=O)CN=C(C2=C1C=CC(=C2)I)C3=CC=CC=C3F	IC50 = 345143739.3 nM	Non binder
T75440	Translocator protein	BC0QU6	2-Oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-7-carbaldehyde	Investigative	44366034	C16H12N2O2	264.28	C1C(=O)NC2=C(C=C(C=C2)C=O)C(=N1)C3=CC=CC=C3	IC50 = 23280912.58 nM	Non binder
T75440	Translocator protein	BCHZ10	7-Bromo-5-(2,6-difluorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one	Investigative	13485706	C16H11BrF2N2O	365.17	CN1C(=O)CN=C(C2=C1C=CC(=C2)Br)C3=C(C=CC=C3F)F	IC50 = 416869383.5 nM	Non binder
T75440	Translocator protein	BEI14D	5-(2-Fluorophenyl)-8-chloro-7-methyl-1H-1,4-benzodiazepin-2(3H)-one	Investigative	44366138	C16H12ClFN2O	302.73	CC1=CC2=C(C=C1Cl)NC(=O)CN=C2C3=CC=CC=C3F	IC50 = 71449632.61 nM	Non binder
T75440	Translocator protein	BFC1L3	2H-1,4-Benzodiazepin-2-one, 5-(2-fluorophenyl)-1,3-dihydro-7-(hydroxyamino)-1-methyl-	Investigative	148760	C16H14FN3O2	299.3	CN1C(=O)CN=C(C2=C1C=CC(=C2)NO)C3=CC=CC=C3F	IC50 = 10423174.29 nM	Non binder
T75440	Translocator protein	BH87IX	7-Ethyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	10264786	C17H16N2O	264.32	CCC1=CC2=C(C=C1)NC(=O)CN=C2C3=CC=CC=C3	IC50 = 27797132.68 nM	Non binder
T75440	Translocator protein	BHKS18	5-(2-Chlorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one	Investigative	528222	C16H12ClN3O3	329.74	CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3Cl	IC50 = 454988060.2 nM	Non binder
T75440	Translocator protein	BI2TE4	5-Phenyl-7-ethenyl-1H-1,4-benzodiazepin-2(3H)-one	Investigative	44366036	C17H14N2O	262.3	C=CC1=CC2=C(C=C1)NC(=O)CN=C2C3=CC=CC=C3	IC50 = 41686938.35 nM	Non binder
T75440	Translocator protein	BLIE59	5-(2-Fluorophenyl)-1-methyl-2-oxo-3H-1,4-benzodiazepine-7-carbonitrile	Investigative	20542073	C17H12FN3O	293.29	CN1C(=O)CN=C(C2=C1C=CC(=C2)C#N)C3=CC=CC=C3F	IC50 = 33342641.28 nM	Non binder
T75440	Translocator protein	BLKV59	8-Chloro-5-(2,6-difluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepine-2-one	Investigative	23275762	C15H9ClF2N2O	306.69	C1C(=O)NC2=C(C=CC(=C2)Cl)C(=N1)C3=C(C=CC=C3F)F	IC50 = 35727283.82 nM	Non binder
T75440	Translocator protein	BMV1G5	7-Azido-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	44366228	C15H10FN5O	295.27	C1C(=O)NC2=C(C=C(C=C2)N=[N+]=[N-])C(=N1)C3=CC=CC=C3F	IC50 = 188799134.9 nM	Non binder
T75440	Translocator protein	BO5G1V	(3R)-7-Chloro-5-(2-fluorophenyl)-3-methyl-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	44366206	C16H12ClFN2O	302.73	C[C@@H]1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F	IC50 = 285759054.3 nM	Non binder
T75440	Translocator protein	BPJC45	7-Fluoro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	75849	C15H11FN2O	254.26	C1C(=O)NC2=C(C=C(C=C2)F)C(=N1)C3=CC=CC=C3	IC50 = 25003453.62 nM	Non binder
T75440	Translocator protein	BR4BL8	5-Phenyl-7,8-dichloro-1-methyl-1H-1,4-benzodiazepin-2(3H)-one	Investigative	44366089	C16H12Cl2N2O	319.2	CN1C(=O)CN=C(C2=CC(=C(C=C21)Cl)Cl)C3=CC=CC=C3	IC50 = 25003453.62 nM	Non binder
T75440	Translocator protein	BRK89P	5-(2,6-Difluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	44366255	C15H10F2N2O	272.25	C1C(=O)NC2=CC=CC=C2C(=N1)C3=C(C=CC=C3F)F	IC50 = 52601726.64 nM	Non binder
T75440	Translocator protein	BS7EO4	7-Fluoro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	44366116	C15H10F2N2O	272.25	C1C(=O)NC2=C(C=C(C=C2)F)C(=N1)C3=CC=CC=C3F	IC50 = 135207256.3 nM	Non binder
T75440	Translocator protein	BSQ57Y	3,7-Dichloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	44366161	C15H9Cl2FN2O	323.1	C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)Cl)F	IC50 = 188799134.9 nM	Non binder
T75440	Translocator protein	BT13FH	5-(2-Fluorophenyl)-7,8-dichloro-1H-1,4-benzodiazepin-2(3H)-one	Investigative	10358803	C15H9Cl2FN2O	323.1	C1C(=O)NC2=CC(=C(C=C2C(=N1)C3=CC=CC=C3F)Cl)Cl	IC50 = 277971326.8 nM	Non binder
T75440	Translocator protein	BU2T3F	1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one	Investigative	76175	C15H12N2O	236.27	C1C(=O)NC2=CC=CC=C2C(=N1)C3=CC=CC=C3	IC50 = 2857590.54 nM	Non binder
T75440	Translocator protein	BU3IQ4	5-(2-Chlorophenyl)-1-methyl-3H-1,4-benzodiazepin-2-one	Investigative	10469149	C16H13ClN2O	284.74	CN1C(=O)CN=C(C2=CC=CC=C21)C3=CC=CC=C3Cl	IC50 = 263026799.2 nM	Non binder
T75440	Translocator protein	BUF05T	7-Amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one	Investigative	23275339	C16H15N3O	265.31	CN1C(=O)CN=C(C2=C1C=CC(=C2)N)C3=CC=CC=C3	IC50 = 2172701.18 nM	Non binder
T75440	Translocator protein	BVE5T7	7-Aminonitrazepam	Investigative	78641	C15H13N3O	251.28	C1C(=O)NC2=C(C=C(C=C2)N)C(=N1)C3=CC=CC=C3	IC50 = 2588212.92 nM	Non binder
T75440	Translocator protein	BW32ZQ	Norflunitrazepam	Investigative	520217	C15H10FN3O3	299.26	C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3F	IC50 = 666806769.2 nM	Non binder
T75440	Translocator protein	BX35CW	7-Chloro-5-(2-chloro-6-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	44366219	C15H9Cl2FN2O	323.1	C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=C(C=CC=C3Cl)F	IC50 = 333426412.8 nM	Non binder
T75440	Translocator protein	BYM73T	7-Nitro-5-[2-(trifluoromethyl)phenyl]-1,3-dihydro-1,4-benzodiazepin-2-one	Investigative	15024	C16H10F3N3O3	349.26	C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3C(F)(F)F	IC50 = 285759054.3 nM	Non binder
T75440	Translocator protein	BZ0DB6	1,7-Dichloro-3-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one	Investigative	44366162	C16H12Cl2N2O	319.2	CC1C(=O)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3)Cl	IC50 = 20417379.45 nM	Non binder
T75440	Translocator protein	BZF09D	1,3-Dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one	Investigative	13292074	C15H11FN2O	254.26	C1C(=O)NC2=CC=CC=C2C(=N1)C3=CC=CC=C3F	IC50 = 47643098.68 nM	Non binder
T75440	Translocator protein	D06DTT	RO-054520	Investigative	193319	C16H13FN2O	268.28	CN1C(=O)CN=C(C2=CC=CC=C21)C3=CC=CC=C3F	IC50 = 71449632.61 nM	Non binder