TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T76910	Glycogen synthase kinase-3 alpha	B0O1LA	4-Arylmaleimide deriv. 6t	Investigative	6539470	C17H14N2O4	310.3	COC1=CC=CC(=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O	IC50 = 472000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B0RUN3	4-Arylmaleimide deriv. 7a	Investigative	6539512	C17H14N2O2	278.3	CN(C1=CC=CC=C1)C2=C(C(=O)NC2=O)C3=CC=CC=C3	IC50 = 2613000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B17JHY	4-Arylmaleimide deriv. 6dd	Investigative	6539503	C17H14N2O2S	310.4	CSC1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC=CC=C3	IC50 = 404000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B1S0FG	4-Arylmaleimide deriv. 6-p	Investigative	6539491	C17H12N2O4	308.29	C1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC=CC(=C3)C(=O)O	IC50 = 291000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B5RE2P	4-Arylmaleimide deriv. 6ll	Investigative	6539511	C17H13N3O4S	355.4	CSC1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 = 392000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B6LC8Q	3-(3-Chloroanilino)-4-phenylpyrrole-2,5-dione	Investigative	6539457	C16H11ClN2O2	298.72	C1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)Cl	IC50 = 301000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B6Q1BN	4-Arylmaleimide deriv. 6b	Investigative	6539452	C16H11ClN2O2	298.72	C1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC=CC=C3Cl	IC50 = 216000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B7IN8W	4-Arylmaleimide deriv. 6gg	Investigative	6539506	C17H13ClN2O2S	344.8	CSC1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC(=CC=C3)Cl	IC50 = 532000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B7K1MT	4-Arylmaleimide deriv. 6y	Investigative	6539475	C16H11ClN2O3	314.72	C1=CC(=CC=C1C2=C(C(=O)NC2=O)NC3=CC=C(C=C3)O)Cl	IC50 = 317000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B7R5FX	4-Arylmaleimide deriv. 7d	Investigative	6539515	C17H13ClN2O2	312.7	CN(C1=CC=CC=C1)C2=C(C(=O)NC2=O)C3=CC=C(C=C3)Cl	IC50 = 2285000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B83KZP	4-Arylmaleimide deriv. 8d	Investigative	6539519	C18H13ClN2O2	324.8	C1CN(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC(=CC=C4)Cl	IC50 = 460000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B8J9IP	4-Arylmaleimide deriv. 8g	Investigative	6539522	C19H16N2O3	320.3	COC1=CC=C(C=C1)C2=C(C(=O)NC2=O)N3CCC4=CC=CC=C43	IC50 = 694000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B8XF4M	4-Arylmaleimide deriv. 6w	Investigative	6539473	C17H14N2O4	310.3	COC1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O	IC50 = 481000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B95DGN	4-Arylmaleimide deriv. 6o	Investigative	6539465	C16H12N2O3	280.28	C1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O	IC50 = 704000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	B9WA8P	1H-Pyrrole-2,5-dione, 3-(4-methoxyphenyl)-4-(phenylamino)-	Investigative	6539456	C17H14N2O3	294.3	COC1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC=CC=C3	IC50 = 390000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BBO23D	4-Arylmaleimide deriv. 6p	Investigative	6539466	C16H11ClN2O3	314.72	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O)Cl	IC50 = 374000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BEP1H3	1-[(4-Methoxyphenyl)methyl]-3-[4-(2H-tetrazol-5-yl)pyridin-2-yl]urea	Investigative	53388146	C15H15N7O2	325.33	COC1=CC=C(C=C1)CNC(=O)NC2=NC=CC(=C2)C3=NNN=N3	IC50 = 370000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BFQO63	4-Arylmaleimide deriv. 8a	Investigative	6539516	C18H13ClN2O2	324.8	C1CN(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC=CC=C4Cl	IC50 = 337000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BG5JE4	4-Arylmaleimide deriv. 6r	Investigative	6539468	C16H11N3O5	325.27	C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O)[N+](=O)[O-]	IC50 = 251000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BHY07R	4-Arylmaleimide deriv. 6e	Investigative	6539455	C16H11ClN2O2	298.72	C1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC=C(C=C3)Cl	IC50 = 514000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BMFC14	4-Arylmaleimide deriv. 6kk	Investigative	6539510	C18H16N2O3S	340.4	COC1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC=C(C=C3)SC	IC50 = 243000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BN71UI	4-Arylmaleimide deriv. 6k	Investigative	6539461	C17H13ClN2O3	328.7	COC1=CC=CC(=C1)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)Cl	IC50 = 257000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BOB58G	4-Arylmaleimide deriv. 6m	Investigative	6539463	C16H10Cl2N2O2	333.2	C1=CC(=CC(=C1)Cl)NC2=C(C(=O)NC2=O)C3=CC=C(C=C3)Cl	IC50 = 447000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BOEF89	4-Arylmaleimide deriv. 6c	Investigative	6539453	C17H14N2O3	294.3	COC1=CC=CC=C1C2=C(C(=O)NC2=O)NC3=CC=CC=C3	IC50 = 216000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BP15RB	4-Arylmaleimide deriv. 7c	Investigative	6539514	C17H13N3O4	323.3	CN(C1=CC=CC=C1)C2=C(C(=O)NC2=O)C3=CC(=CC=C3)[N+](=O)[O-]	IC50 = 1398000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BQ8V2I	4-Arylmaleimide deriv. 6jj	Investigative	6539509	C17H13ClN2O2S	344.8	CSC1=CC=C(C=C1)NC2=C(C(=O)NC2=O)C3=CC=C(C=C3)Cl	IC50 = 529000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BQL98K	1-(4-Cyanopyridin-2-yl)-3-[(4-methoxyphenyl)methyl]urea	Investigative	56675716	C15H14N4O2	282.3	COC1=CC=C(C=C1)CNC(=O)NC2=NC=CC(=C2)C#N	IC50 = 1120000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BRJ86A	4-Arylmaleimide deriv. 8f	Investigative	6539521	C18H13ClN2O2	324.8	C1CN(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC=C(C=C4)Cl	IC50 = 1412000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BS6C2J	4-Arylmaleimide deriv. 6-v	Investigative	6539497	C18H14N2O5	338.3	COC1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC=CC(=C3)C(=O)O	IC50 = 214000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BSZ98H	1-[(4-Methoxyphenyl)methyl]-3-(6-nitro-1,3-benzothiazol-2-yl)urea	Investigative	56668847	C16H14N4O4S	358.4	COC1=CC=C(C=C1)CNC(=O)NC2=NC3=C(S2)C=C(C=C3)[N+](=O)[O-]	IC50 = 220000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BTC34Z	4-Arylmaleimide deriv. 6q	Investigative	6539467	C17H14N2O4	310.3	COC1=CC=CC=C1C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O	IC50 = 259000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BU50GW	4-Arylmaleimide deriv. 7b	Investigative	6539513	C18H16N2O3	308.3	CN(C1=CC=CC=C1)C2=C(C(=O)NC2=O)C3=CC(=CC=C3)OC	IC50 > 4500000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BUX7Y4	4-Arylmaleimide deriv. 6v	Investigative	6539472	C16H11ClN2O3	314.72	C1=CC(=CC(=C1)O)NC2=C(C(=O)NC2=O)C3=CC=C(C=C3)Cl	IC50 = 407000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BVR8Y0	4-Arylmaleimide deriv. 6u	Investigative	6539471	C16H11N3O5	325.27	C1=CC(=CC(=C1)[N+](=O)[O-])C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O	IC50 = 236000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BVXE92	4-Arylmaleimide deriv. 6hh	Investigative	6539507	C18H16N2O3S	340.4	COC1=CC=CC(=C1)C2=C(C(=O)NC2=O)NC3=CC=C(C=C3)SC	IC50 = 203000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	BWD35A	4-Arylmaleimide deriv. 6s	Investigative	6539469	C16H11ClN2O3	314.72	C1=CC(=CC(=C1)Cl)C2=C(C(=O)NC2=O)NC3=CC(=CC=C3)O	IC50 = 1478000 nM	Non binder
T76910	Glycogen synthase kinase-3 alpha	D01OJG	3-phenyl-4-(phenylamino)-1H-pyrrole-2,5-dione	Investigative	6539451	C16H12N2O2	264.28	C1=CC=C(C=C1)C2=C(C(=O)NC2=O)NC3=CC=CC=C3	IC50 = 529000 nM	Non binder