TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T77365	Adenosine A2a receptor	D04OSE	Nifedipine	Approved	4485	C17H18N2O6	346.3	CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC	Ki = 244000 nM	Non binder
T77365	Adenosine A2a receptor	B15PSV	(4S)-1-Benzyl-4-[(4-methoxyphenyl)methyl]-4,5-dihydroimidazol-2-amine;hydrochloride	Investigative	127039488	C18H22ClN3O	331.8	COC1=CC=C(C=C1)C[C@H]2CN(C(=N2)N)CC3=CC=CC=C3.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	B21SNW	(8As)-2-benzyl-1,5,6,7,8,8a-hexahydroimidazo[1,5-a]pyridin-3-imine;hydrochloride	Investigative	127040399	C14H20ClN3	265.78	C1CCN2[C@@H](C1)CN(C2=N)CC3=CC=CC=C3.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	B3Z1QH	1-Cyclopentyl-4,6-dimethyl-1,4-dihydro-[1,2,3]triazolo[4,5-d]pyrimidine-5,7-dione	Investigative	10444746	C11H15N5O2	249.27	CN1C2=C(C(=O)N(C1=O)C)N(N=N2)C3CCCC3	Ki = 292000 nM	Non binder
T77365	Adenosine A2a receptor	B59WLO	(10As)-2-(2-pyridin-2-ylethyl)-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinolin-3-imine;dihydrochloride	Investigative	127038104	C18H22Cl2N4	365.3	C1[C@H]2CN(C(=N)N2CC3=CC=CC=C31)CCC4=CC=CC=N4.Cl.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	B8LEK3	4-[[(4S)-2-Amino-1-benzyl-4,5-dihydroimidazol-4-yl]methyl]phenol;hydrochloride	Investigative	127039486	C17H20ClN3O	317.8	C1[C@@H](N=C(N1CC2=CC=CC=C2)N)CC3=CC=C(C=C3)O.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	BCON06	(10As)-2-(2-morpholin-4-ylethyl)-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinolin-3-imine;dihydrochloride	Investigative	127038106	C17H26Cl2N4O	373.3	C1COCCN1CCN2C[C@@H]3CC4=CC=CC=C4CN3C2=N.Cl.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	BFX6B1	(4S)-1-Benzyl-4-methyl-4,5-dihydroimidazol-2-amine;hydrochloride	Investigative	127040044	C11H16ClN3	225.72	C[C@H]1CN(C(=N1)N)CC2=CC=CC=C2.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	BH4DL9	(10As)-2-hexyl-1,5,10,10a-tetrahydroimidazo[1,5-b]isoquinolin-3-imine;hydrochloride	Investigative	127041683	C17H26ClN3	307.9	CCCCCCN1C[C@@H]2CC3=CC=CC=C3CN2C1=N.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	BJ2G5D	(4S)-1,4-Dibenzyl-4,5-dihydroimidazol-2-amine;hydrochloride	Investigative	127039480	C17H20ClN3	301.8	C1[C@@H](N=C(N1CC2=CC=CC=C2)N)CC3=CC=CC=C3.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	BOZB05	(2-Amino-4H-indeno[1,2-d][1,3]thiazol-5-yl) acetate;hydroiodide	Investigative	9976651	C12H11IN2O2S	374.2	CC(=O)OC1=CC=CC2=C1CC3=C2N=C(S3)N.I	EC50 = 15848931.92 nM	Non binder
T77365	Adenosine A2a receptor	BT7YV8	(4S)-1-Benzyl-4-[(4-fluorophenyl)methyl]-4,5-dihydroimidazol-2-amine;hydrochloride	Investigative	127039484	C17H19ClFN3	319.8	C1[C@@H](N=C(N1CC2=CC=CC=C2)N)CC3=CC=C(C=C3)F.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	BXHM12	1,4-Dibenzyl-3-methylimidazolidin-2-imine;hydrochloride	Investigative	127039482	C18H22ClN3	315.8	CN1C(CN(C1=N)CC2=CC=CC=C2)CC3=CC=CC=C3.Cl	Ki > 200000 nM	Non binder
T77365	Adenosine A2a receptor	BY8WZ3	2-Cyclohexyl-4,6-dimethyl-2,4-dihydro-[1,2,3]triazolo[4,5-d]pyrimidine-5,7-dione	Investigative	10106813	C12H17N5O2	263.3	CN1C2=NN(N=C2C(=O)N(C1=O)C)C3CCCCC3	Ki = 250000 nM	Non binder