TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T77913	Histamine H1 receptor	D01JUF	Phentolamine	Approved	5775	C17H19N3O	281.35	CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O	IC50 = 316227.77 nM	Non binder
T77913	Histamine H1 receptor	B06RGY	2-[3-Phenyl-3-(4-methylphenyl)propyl]-1H-imidazole-4-(ethanamine)	Investigative	10615605	C21H25N3	319.4	CC1=CC=C(C=C1)C(CCC2=NC=C(N2)CCN)C3=CC=CC=C3	Ki = 316000000000000 nM	Non binder
T77913	Histamine H1 receptor	B0WTH9	2-(12-Aminododecyl)pyridine	Investigative	11300006	C17H30N2	262.4	C1=CC=NC(=C1)CCCCCCCCCCCCN	Ki = 1000000000000000 nM	Non binder
T77913	Histamine H1 receptor	B1DBY6	12-(1H-Imidazol-5-yl)dodecan-1-amine	Investigative	11459394	C15H29N3	251.41	C1=C(NC=N1)CCCCCCCCCCCCN	Ki = 1000000000000000 nM	Non binder
T77913	Histamine H1 receptor	B2UH3W	10-Pyridin-2-yldecan-1-amine	Investigative	11172377	C15H26N2	234.38	C1=CC=NC(=C1)CCCCCCCCCCN	Ki = 79400000000000 nM	Non binder
T77913	Histamine H1 receptor	B30ZQL	2-(2,2-Diphenylethyl)-1H-imidazole-4-ethanamine	Investigative	10685002	C19H21N3	291.4	C1=CC=C(C=C1)C(CC2=NC=C(N2)CCN)C3=CC=CC=C3	Ki = 126000000000000 nM	Non binder
T77913	Histamine H1 receptor	B3KVQ8	2-[3-(Trifluoromethyl)phenyl]thiazole-4-ethanamine	Investigative	10812715	C12H11F3N2S	272.29	C1=CC(=CC(=C1)C(F)(F)F)C2=NC(=CS2)CCN	Ki = 79400000000000 nM	Non binder
T77913	Histamine H1 receptor	B4T3RA	2-Benzylthiazole-4-ethanamine	Investigative	44369859	C12H14N2S	218.32	C1=CC=C(C=C1)CC2=NC(=CS2)CCN	Ki = 15800000000000 nM	Non binder
T77913	Histamine H1 receptor	B6IR1G	2-[2-(3-Cyclohexyl-3-phenylpropyl)-1H-imidazol-5-yl]ethanamine	Investigative	44369867	C20H29N3	311.5	C1CCC(CC1)C(CCC2=NC=C(N2)CCN)C3=CC=CC=C3	Ki = 100000000000000 nM	Non binder
T77913	Histamine H1 receptor	B7YAT3	2-(3,3-Diphenylpropyl)-4-(2-pyrrolizinoethyl)-1H-imidazole	Investigative	10689833	C24H29N3	359.5	C1CCN(C1)CCC2=CN=C(N2)CCC(C3=CC=CC=C3)C4=CC=CC=C4	Ki = 398000000000000 nM	Non binder
T77913	Histamine H1 receptor	BA64TQ	2-(2-Phenyl-thiazol-4-yl)-ethylamine	Investigative	22690260	C11H12N2S	204.29	C1=CC=C(C=C1)C2=NC(=CS2)CCN	Ki = 31600000000000 nM	Non binder
T77913	Histamine H1 receptor	BBJM89	14-(1H-Imidazol-5-yl)tetradecan-1-amine	Investigative	11346501	C17H33N3	279.5	C1=C(NC=N1)CCCCCCCCCCCCCCN	Ki = 3980000000000000 nM	Non binder
T77913	Histamine H1 receptor	BBQ1K0	10-Pyridin-4-yldecan-1-amine	Investigative	11253315	C15H26N2	234.38	C1=CN=CC=C1CCCCCCCCCCN	Ki = 200000000000000 nM	Non binder
T77913	Histamine H1 receptor	BCH05I	1H-Imidazole-5-decanamine	Investigative	10263017	C13H25N3	223.36	C1=C(NC=N1)CCCCCCCCCCN	Ki = 200000000000000 nM	Non binder
T77913	Histamine H1 receptor	BCVT08	10-Pyridin-3-yldecan-1-amine	Investigative	11241807	C15H26N2	234.38	C1=CC(=CN=C1)CCCCCCCCCCN	Ki = 126000000000000 nM	Non binder
T77913	Histamine H1 receptor	BGV6Z8	11-(1H-Imidazol-5-yl)undecan-1-amine	Investigative	11333854	C14H27N3	237.38	C1=C(NC=N1)CCCCCCCCCCCN	Ki = 398000000000000 nM	Non binder
T77913	Histamine H1 receptor	BI7Y0X	5-(10-Pyrrolidin-1-yldecyl)-1H-imidazole	Investigative	11231249	C17H31N3	277.4	C1CCN(C1)CCCCCCCCCCC2=CN=CN2	Ki = 251000000000000 nM	Non binder
T77913	Histamine H1 receptor	BJ18UY	5-(12-Pyrrolidin-1-yldodecyl)-1H-imidazole	Investigative	11358657	C19H35N3	305.5	C1CCN(C1)CCCCCCCCCCCCC2=CN=CN2	Ki = 501000000000000 nM	Non binder
T77913	Histamine H1 receptor	BK8L0R	13-(1H-Imidazol-5-yl)tridecan-1-amine	Investigative	11288570	C16H31N3	265.44	C1=C(NC=N1)CCCCCCCCCCCCCN	Ki = 2510000000000000 nM	Non binder
T77913	Histamine H1 receptor	BK9ZE1	2-(4,4-Diphenylbutyl)-1H-imidazole-4-ethanamine	Investigative	10471211	C21H25N3	319.4	C1=CC=C(C=C1)C(CCCC2=NC=C(N2)CCN)C3=CC=CC=C3	Ki = 631000000000000 nM	Non binder
T77913	Histamine H1 receptor	BNHX18	2-[3-Phenyl-3-(4-bromophenyl)propyl]-1H-imidazole-4-(ethanamine)	Investigative	10596163	C20H22BrN3	384.3	C1=CC=C(C=C1)C(CCC2=NC=C(N2)CCN)C3=CC=C(C=C3)Br	Ki = 398000000000000 nM	Non binder
T77913	Histamine H1 receptor	BO1BS6	6-(1H-Imidazol-5-yl)hexan-1-amine	Investigative	10261471	C9H17N3	167.25	C1=C(NC=N1)CCCCCCN	Ki = 2000000000000 nM	Non binder
T77913	Histamine H1 receptor	BO2R8Q	5-(8-Pyrrolidin-1-yloctyl)-1H-imidazole	Investigative	11230427	C15H27N3	249.39	C1CCN(C1)CCCCCCCCC2=CN=CN2	Ki = 251000000000000 nM	Non binder
T77913	Histamine H1 receptor	BOE68K	12-Pyridin-4-yldodecan-1-amine	Investigative	10264715	C17H30N2	262.4	C1=CN=CC=C1CCCCCCCCCCCCN	Ki = 251000000000000 nM	Non binder
T77913	Histamine H1 receptor	BQY52G	12-(3-Pyridyl)-1-dodecanamine	Investigative	10890691	C17H30N2	262.4	C1=CC(=CN=C1)CCCCCCCCCCCCN	Ki = 251000000000000 nM	Non binder
T77913	Histamine H1 receptor	BS01CJ	2-[2-[3-(Trifluoromethyl)phenyl]-1H-imidazol-5-yl]ethanamine	Investigative	5310982	C12H12F3N3	255.24	C1=CC(=CC(=C1)C(F)(F)F)C2=NC=C(N2)CCN	Ki = 251000000000000 nM	Non binder
T77913	Histamine H1 receptor	BS0V5D	9-Pyridin-2-ylnonan-1-amine	Investigative	11816882	C14H24N2	220.35	C1=CC=NC(=C1)CCCCCCCCCN	Ki = 31600000000000 nM	Non binder
T77913	Histamine H1 receptor	BX6AO5	2-(5,5-Diphenylpentyl)-1H-imidazole-4-ethanamine	Investigative	10246247	C22H27N3	333.5	C1=CC=C(C=C1)C(CCCCC2=NC=C(N2)CCN)C3=CC=CC=C3	Ki = 794000000000000 nM	Non binder
T77913	Histamine H1 receptor	BX6YB5	2-(3-Chlorobenzyl)thiazole-4-ethanamine	Investigative	10669501	C12H13ClN2S	252.76	C1=CC(=CC(=C1)Cl)CC2=NC(=CS2)CCN	Ki = 31600000000000 nM	Non binder
T77913	Histamine H1 receptor	BY8P4D	8-(1H-Imidazol-5-yl)octan-1-amine	Investigative	10420190	C11H21N3	195.3	C1=C(NC=N1)CCCCCCCCN	Ki = 25100000000000 nM	Non binder
T77913	Histamine H1 receptor	BYQ39O	1H-Imidazole-5-nonanamine	Investigative	11264275	C12H23N3	209.33	C1=C(NC=N1)CCCCCCCCCN	Ki = 50100000000000 nM	Non binder
T77913	Histamine H1 receptor	BYZ0A7	(+)-(S)-N,N-Dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)benzo[b]thiophen-2-yl)ethanamine	Investigative	11551351	C19H22N2S	310.5	C[C@H](C1=CC=CC=N1)C2=C(SC3=CC=CC=C32)CCN(C)C	IC50 = 256000 nM	Non binder