TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T83391	Fructose-1,6-bisphosphatase 1	B12FIB	1-(3-Chlorophenylsulfonyl)-3-(2-(methylthio)ethyl)urea	Investigative	44587909	C10H13ClN2O3S2	308.8	CSCCNC(=O)NS(=O)(=O)C1=CC(=CC=C1)Cl	IC50 = 277143 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	B1SCF8	Urea, 1-propyl-3-(m-tolylsulfonyl)-	Investigative	211386	C11H16N2O3S	256.32	CCCNC(=O)NS(=O)(=O)C1=CC=CC(=C1)C	IC50 = 320180 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	B27AIR	2-Amino-4,5-dihydronaphtho[1,2-d]thiazol-9-yl dihydrogen phosphate	Investigative	45487808	C11H11N2O4PS	298.26	C1CC2=C(C3=C1C=CC=C3OP(=O)(O)O)N=C(S2)N	IC50 = 335000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	B2DGO8	{[(6-Amino-9-phenethyl-9H-purin-8-ylmethyl)-amino]-methyl}-phosphonic acid	Investigative	42637715	C15H19N6O3P	362.32	C1=CC=C(C=C1)CCN2C(=NC3=C(N=CN=C32)N)CNCP(=O)(O)O	IC50 > 500000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	B39XLS	[3-(6-Amino-9-phenethyl-9H-purin-8-yl)-propyl]-phosphinic Acid	Investigative	44591798	C16H19N5O2P+	344.33	C1=CC=C(C=C1)CCN2C(=NC3=C(N=CN=C32)N)CCC[P+](=O)O	IC50 > 1000000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	B6XE2V	[2-(6-Amino-9-phenethyl-9H-purin-8-yl)-1-methyl-ethyl]-phosphinic Acid	Investigative	44591799	C16H19N5O2P+	344.33	CC(CC1=NC2=C(N=CN=C2N1CCC3=CC=CC=C3)N)[P+](=O)O	IC50 > 1000000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BC4LJ2	2-Amino-4,5-dihydronaphtho[1,2-d]thiazol-9-ylphosphonic acid	Investigative	45487822	C11H11N2O3PS	282.26	C1CC2=C(C3=C1C=CC=C3P(=O)(O)O)N=C(S2)N	IC50 = 354000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BCVN80	[5-(6-Dimethylamino-9-phenethyl-9H-purin-8-yl)-furan-2-yl]-phosphonic Acid	Investigative	42637785	C19H20N5O4P	413.4	CN(C)C1=NC=NC2=C1N=C(N2CCC3=CC=CC=C3)C4=CC=C(O4)P(=O)(O)O	IC50 = 250000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BEO5H8	2-Amino-8H-indeno[1,2-d]thiazol-5-yl dihydrogen phosphate	Investigative	45487827	C10H9N2O4PS	284.23	C1C2=C(C=C(C=C2)OP(=O)(O)O)C3=C1SC(=N3)N	IC50 = 307000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BMJ83Z	(+)-Usnic acid	Investigative	24211; 478125	C18H16O7	344.3	CC1=C(C(=C2C(=C1O)C3(C(=CC(=C(C3=O)C(=O)C)O)O2)C)C(=O)C)O	IC50 = 371000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BP9O7W	[2-(6-Amino-9-phenethyl-9H-purin-8-yl)-ethoxy]-phosphinic Acid	Investigative	44591800	C15H17N5O3P+	346.3	C1=CC=C(C=C1)CCN2C(=NC3=C(N=CN=C32)N)CCO[P+](=O)O	IC50 > 1000000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BTJ31P	2-Amino-4,5-dihydronaphtho[1,2-d]thiazol-7-ylphosphonic acid	Investigative	45487819	C11H11N2O3PS	282.26	C1CC2=C(C3=C1C=C(C=C3)P(=O)(O)O)N=C(S2)N	IC50 = 354000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BTVH78	[2-(6-Amino-9-phenethyl-9H-purine-8-sulfonyl)-ethyl]-phosphonic Acid	Investigative	42637925	C15H18N5O5PS	411.4	C1=CC=C(C=C1)CCN2C3=NC=NC(=C3N=C2S(=O)(=O)CCP(=O)(O)O)N	IC50 > 1000000 nM	Non binder
T83391	Fructose-1,6-bisphosphatase 1	BUO1H9	1-(3-Chlorophenylsulfonyl)-3-propylurea	Investigative	44587904	C10H13ClN2O3S	276.74	CCCNC(=O)NS(=O)(=O)C1=CC(=CC=C1)Cl	IC50 = 234231 nM	Non binder