TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T84173	Glucosylceramidase	D0HR8Z	Miglustat	Approved	51634	C10H21NO4	219.28	CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O	IC50 = 259000 nM	Non binder
T84173	Glucosylceramidase	D0RE9C	Lucerastat	Phase 1/2	501391	C10H21NO4	219.28	CCCCN1C[C@@H]([C@H]([C@H]([C@H]1CO)O)O)O	IC50 = 320000 nM	Non binder
T84173	Glucosylceramidase	B07DXW	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol	Investigative	118719900	C26H33NO5	439.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC2=CC3=CC=CC=C3C4=CC=CC=C42)CO)O)O)O	IC50 = 600000 nM	Non binder
T84173	Glucosylceramidase	B0F4GE	6-Hydroxymethyl-2-methoxy-5-(pyridin-2-ylsulfanyl)-tetrahydro-pyran-3,4-diol	Investigative	44377855	C12H17NO5S	287.33	COC1C(C(C(C(O1)CO)SC2=CC=CC=N2)O)O	Ki = 8000000 nM	Non binder
T84173	Glucosylceramidase	B0HKC3	Methyl 16-[[(3aS,5R,6S,7S,7aR)-6,7-dihydroxy-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[2,3-d][1,3]oxazol-2-yl]sulfanyl]hexadecanoate	Investigative	118725788	C24H43NO7S	489.7	COC(=O)CCCCCCCCCCCCCCCSC1=N[C@@H]2[C@H](O1)[C@H]([C@@H]([C@H](O2)CO)O)O	IC50 = 300000 nM	Non binder
T84173	Glucosylceramidase	B0URS2	1-Octylpiperidine-3beta,4beta,5alpha-triol	Investigative	44566056	C13H27NO3	245.36	CCCCCCCCN1C[C@H](C([C@@H](C1)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	B14XFD	(1S,2S,3S,6R)-6-(Cyclohexylmethylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034626	C13H24ClNO3	277.79	C1CCC(CC1)CN[C@@H]2C=C[C@@H]([C@@H]([C@H]2O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B1A4ZS	(3R,4R,5R)-3,4,5-Trihydroxy-1-(6-hydroxyhexyl)piperidin-2-one	Investigative	44566036	C11H21NO5	247.29	C1[C@H]([C@H]([C@H](C(=O)N1CCCCCCO)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	B1UVQ2	(3R,4R,5R)-1-Decyl-3,4,5-trihydroxypiperidin-2-one	Investigative	44566033	C15H29NO4	287.39	CCCCCCCCCCN1C[C@H]([C@H]([C@H](C1=O)O)O)O	IC50 = 463000 nM	Non binder
T84173	Glucosylceramidase	B1Z9VG	(1R,2R,3R)-3-(Hydroxymethyl)-4-pentylcyclohexane-1,2-diol	Investigative	118986927	C12H24O3	216.32	CCCCCC1CC[C@H]([C@@H]([C@H]1CO)O)O	EC50 = 266100 nM	Non binder
T84173	Glucosylceramidase	B2GCS5	4,5,6,7-Tetrachloro-2-(5-phenylpentyl)isoindoline-1,3-dione	Investigative	10788794	C19H15Cl4NO2	431.1	C1=CC=C(C=C1)CCCCCN2C(=O)C3=C(C2=O)C(=C(C(=C3Cl)Cl)Cl)Cl	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	B2H8XO	Rel-(1R,2S,4R,5S)-6-((1-(3-(3-methoxypropoxy)propyl)-1H-1,2,3-triazol-4-yl)methylamino)cyclohexane-1,2,3,4,5-pentaol	Investigative	52937715	C16H30N4O7	390.43	COCCCOCCCN1C=C(N=N1)CNC2[C@@H]([C@H](C([C@H]([C@@H]2O)O)O)O)O	IC50 = 466000 nM	Non binder
T84173	Glucosylceramidase	B2VQ4C	(3S,4R,5S)-1-Decyl-3,4,5-trihydroxypiperidin-2-one	Investigative	44140356	C15H29NO4	287.39	CCCCCCCCCCN1C[C@@H]([C@H]([C@@H](C1=O)O)O)O	IC50 = 295000 nM	Non binder
T84173	Glucosylceramidase	B32YZM	N-Phenylphthalimide	Investigative	68215	C14H9NO2	223.23	C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3C2=O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	B3J9XN	(1R,2S,3r,4R,5S,6s)-6-(3-(1-Hexyl-1H-1,2,3-triazol-4-yl)propylamino)cyclohexane-1,2,3,4,5-pentaol	Investigative	46867665	C17H32N4O5	372.5	CCCCCCN1C=C(N=N1)CCCNC2[C@@H]([C@H](C([C@H]([C@@H]2O)O)O)O)O	IC50 = 257000 nM	Non binder
T84173	Glucosylceramidase	B3MQU8	(1S,2S,3S,6R)-6-(Benzylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127036664	C13H18ClNO3	271.74	C1=CC=C(C=C1)CN[C@@H]2C=C[C@@H]([C@@H]([C@H]2O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B3R2DQ	N-Butyl-L-ido-1-deoxynojirimycin	Investigative	23622616	C10H21NO4	219.28	CCCCN1C[C@@H]([C@H]([C@@H]([C@@H]1CO)O)O)O	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B42AHD	(3S,4R,5S)-3,4,5-Trihydroxy-1-(6-hydroxyhexyl)piperidin-2-one	Investigative	44140485	C11H21NO5	247.29	C1[C@@H]([C@H]([C@@H](C(=O)N1CCCCCCO)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	B45ORD	5-Methylpiperidine-3,4-diol	Investigative	10011928	C6H13NO2	131.17	CC1CNCC(C1O)O	IC50 = 500000 nM	Non binder
T84173	Glucosylceramidase	B4DE0G	N-(Adamantan-1-yl)-4-[(2S,3R,4R,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]butanamide	Investigative	16100284	C20H34N2O5	382.5	C1C2CC3CC1CC(C2)(C3)NC(=O)CCCN4[C@@H]([C@H]([C@@H]([C@@H]4CO)O)O)CO	IC50 = 507000 nM	Non binder
T84173	Glucosylceramidase	B4J7EQ	(3S,4R,5R)-1-[2-(Dipropylamino)ethyl]-3,4,5-trihydroxypiperidin-2-one	Investigative	44566018	C13H26N2O4	274.36	CCCN(CCC)CCN1C[C@H]([C@H]([C@@H](C1=O)O)O)O	IC50 = 253000 nM	Non binder
T84173	Glucosylceramidase	B57EDN	(1S,2S,3S,6R)-6-(Butylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127035143	C10H20ClNO3	237.72	CCCCN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B57KUY	(1S,2S,3S,6R)-6-(2-Methylpropylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034622	C10H20ClNO3	237.72	CC(C)CN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B58ODL	(2R,3S,4R,5S,6S)-5-[2-[(2S,3S,4R,5S,6R)-4,5-Dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]sulfanylpyridin-3-yl]oxy-6-(hydroxymethyl)-2-methoxyoxane-3,4-diol	Investigative	71717833	C19H29NO11S	479.5	CO[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)CO)OC2=C(N=CC=C2)S[C@@H]3[C@@H](O[C@H]([C@H]([C@H]3O)O)OC)CO)O)O	Ki = 5500000 nM	Non binder
T84173	Glucosylceramidase	B5DJF2	(1S,2S,3S,6R)-6-(Cyclohexylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034628	C12H22ClNO3	263.76	C1CCC(CC1)N[C@@H]2C=C[C@@H]([C@@H]([C@H]2O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B5HRF7	(2S,3R,4R,5S,6S)-2-(Hydroxymethyl)-6-propylpiperidine-3,4,5-triol	Investigative	10352906	C9H19NO4	205.25	CCC[C@@H]1[C@@H]([C@H]([C@@H]([C@@H](N1)CO)O)O)O	IC50 = 487000 nM	Non binder
T84173	Glucosylceramidase	B5XES6	4,5,6,7-Tetrachloro-2-(6-phenyl-hexyl)-isoindole-1,3-dione	Investigative	44267363	C20H17Cl4NO2	445.2	C1=CC=C(C=C1)CCCCCCN2C(=O)C3=C(C2=O)C(=C(C(=C3Cl)Cl)Cl)Cl	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	B60HMV	(1S,2S,3S,6R)-6-(Pentan-3-ylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127035326	C11H22ClNO3	251.75	CCC(CC)N[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B6RN4L	(1S,2S,3S,6R)-4-Methyl-6-(octylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	71573724	C15H30ClNO3	307.85	CCCCCCCCN[C@@H]1C=C([C@@H]([C@@H]([C@H]1O)O)O)C.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B6ZUD3	(1S,2S,3S,6R)-6-(3-Methylbutylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034630	C11H22ClNO3	251.75	CC(C)CCN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B71MVP	6-Hydroxymethyl-5-(3-hydroxy-6-methyl-pyridin-2-ylsulfanyl)-2-methoxy-tetrahydro-pyran-3,4-diol	Investigative	44378065	C13H19NO6S	317.36	CC1=NC(=C(C=C1)O)SC2C(OC(C(C2O)O)OC)CO	Ki = 4500000 nM	Non binder
T84173	Glucosylceramidase	B71ZIU	(1S,2S,3S,6R)-4-(Hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	11359212	C15H30ClNO4	323.85	CCCCCCCCN[C@@H]1C=C([C@@H]([C@@H]([C@H]1O)O)O)CO.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B7NVQ0	(2R,3R,4R,5S)-2-Methyl-tetrahydro-pyran-3,4,5-triol	Investigative	11744779	C6H12O4	148.16	C[C@@H]1[C@@H]([C@@H]([C@H](CO1)O)O)O	Ki = 42000000 nM	Non binder
T84173	Glucosylceramidase	B7U3LJ	5-Methylene-piperidine-3,4-diol	Investigative	44367875	C6H11NO2	129.16	C=C1CNCC(C1O)O	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B83PDH	Rel-(1R,2S,4R,5S)-6-((1-(3-(3-(3-methoxypropoxy)propoxy)propyl)-1H-1,2,3-triazol-4-yl)methylamino)cyclohexane-1,2,3,4,5-pentaol	Investigative	52937814	C19H36N4O8	448.5	COCCCOCCCOCCCN1C=C(N=N1)CNC2[C@@H]([C@H](C([C@H]([C@@H]2O)O)O)O)O	IC50 = 453000 nM	Non binder
T84173	Glucosylceramidase	B95YLH	(1S,2S,3S,6R)-6-(Pentylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127035145	C11H22ClNO3	251.75	CCCCCN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B96ETW	2-Phenylamino-4,5,6,6a-tetrahydro-3aH-cyclopentaoxazole-4,5,6-triol	Investigative	44322665	C12H14N2O4	250.25	C1=CC=C(C=C1)NC2=NC3C(C(C(C3O2)O)O)O	IC50 > 300000 nM	Non binder
T84173	Glucosylceramidase	B9D3TE	(1S,2S,3S,6R)-6-(3-Hydroxypropylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034620	C9H18ClNO4	239.69	C1=C[C@@H]([C@@H]([C@H]([C@@H]1NCCCO)O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	B9T6OM	N-Heptyl-L-ido-1-deoxynojirimycin	Investigative	25010186	C13H27NO4	261.36	CCCCCCCN1C[C@@H]([C@H]([C@@H]([C@@H]1CO)O)O)O	IC50 = 700000 nM	Non binder
T84173	Glucosylceramidase	BA6CI1	16-[[(3As,5R,6S,7S,7aR)-6,7-dihydroxy-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[2,3-d][1,3]oxazol-2-yl]sulfanyl]hexadecanoic acid	Investigative	118725793	C23H41NO7S	475.6	C(CCCCCCCC(=O)O)CCCCCCCSC1=N[C@@H]2[C@H](O1)[C@H]([C@@H]([C@H](O2)CO)O)O	IC50 = 420000 nM	Non binder
T84173	Glucosylceramidase	BAF4R5	3beta,4alpha,5alpha-Trihydroxypiperidin-2-one	Investigative	11062529	C5H9NO4	147.13	C1[C@H]([C@H]([C@@H](C(=O)N1)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BB50VJ	(3S,4R,5R)-3,4,5-Trihydroxy-1-(2-hydroxyethyl)piperidin-2-one	Investigative	44566015	C7H13NO5	191.18	C1[C@H]([C@H]([C@@H](C(=O)N1CCO)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BB6LI7	2-(3-Phenylpropyl)isoindole-1,3-dione	Investigative	7663529	C17H15NO2	265.31	C1=CC=C(C=C1)CCCN2C(=O)C3=CC=CC=C3C2=O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BBHQ70	Rel-(1R,2S,4R,5S)-6-((1-(3-(3-tert-butoxypropoxy)propyl)-1H-1,2,3-triazol-4-yl)methylamino)cyclohexane-1,2,3,4,5-pentaol	Investigative	52937815	C19H36N4O7	432.5	CC(C)(C)OCCCOCCCN1C=C(N=N1)CNC2[C@@H]([C@H](C([C@H]([C@@H]2O)O)O)O)O	IC50 = 325000 nM	Non binder
T84173	Glucosylceramidase	BC02FG	4,5,6,7-Tetrachloro-2-(3-phenylpropyl)isoindoline-1,3-dione	Investigative	10739903	C17H11Cl4NO2	403.1	C1=CC=C(C=C1)CCCN2C(=O)C3=C(C2=O)C(=C(C(=C3Cl)Cl)Cl)Cl	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BCF6W4	5-(3-Hydroxy-6-hydroxymethyl-pyridin-2-ylsulfanyl)-6-hydroxymethyl-2-methoxy-tetrahydro-pyran-3,4-diol	Investigative	44378051	C13H19NO7S	333.36	COC1C(C(C(C(O1)CO)SC2=C(C=CC(=N2)CO)O)O)O	Ki = 4000000 nM	Non binder
T84173	Glucosylceramidase	BCV61X	(2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-triol	Investigative	11116404	C6H12FNO3	165.16	C1[C@@H]([C@H]([C@@H]([C@H](N1)CF)O)O)O	Ki = 380000 nM	Non binder
T84173	Glucosylceramidase	BDZ60T	(2S,3R,4R,5S)-1-[2,2-Difluoro-5-[(4-phenylphenyl)methoxy]pentyl]-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	118720307	C24H31F2NO5	451.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CC(CCCOCC2=CC=C(C=C2)C3=CC=CC=C3)(F)F)CO)O)O)O	IC50 = 500000 nM	Non binder
T84173	Glucosylceramidase	BE1U2X	2-Morpholinoethanol	Investigative	61163	C6H13NO2	131.17	C1COCCN1CCO	Ki = 620000 nM	Non binder
T84173	Glucosylceramidase	BE1U6M	N-Hexoxypentyl-1-deoxynojirimycin	Investigative	53321623	C17H35NO5	333.5	CCCCCCOCCCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O	IC50 = 205000 nM	Non binder
T84173	Glucosylceramidase	BFI2G6	2-Anilino-6a-(hydroxymethyl)-3a,4,5,6-tetrahydrocyclopenta[d][1,3]oxazole-4,5,6-triol	Investigative	21479008	C13H16N2O5	280.28	C1=CC=C(C=C1)NC2=NC3C(C(C(C3(O2)CO)O)O)O	IC50 > 300000 nM	Non binder
T84173	Glucosylceramidase	BG7WR8	2-Anilino-4-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazole-5,6-diol	Investigative	44322890	C13H16N2O4	264.28	C1=CC=C(C=C1)NC2=NC3C(C(C(C3O2)O)O)CO	IC50 > 300000 nM	Non binder
T84173	Glucosylceramidase	BHZ70X	N-Butoxypentyl-L-ido-1-deoxynojirimycin	Investigative	53320433	C15H31NO5	305.41	CCCCOCCCCCN1C[C@@H]([C@H]([C@@H]([C@@H]1CO)O)O)O	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BIX53M	alpha-1-C-Propyl-DNJ	Investigative	10932614	C9H19NO4	205.25	CCC[C@@H]1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O	IC50 = 400000 nM	Non binder
T84173	Glucosylceramidase	BJ0PV8	4-Amino-2-phenyl-1H-isoindole-1,3(2H)-dione	Investigative	3448473	C14H10N2O2	238.24	C1=CC=C(C=C1)N2C(=O)C3=C(C2=O)C(=CC=C3)N	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BJ3GL9	(3S,4R,5R)-3,4,5-Trihydroxy-1-(2-propoxyethyl)piperidin-2-one	Investigative	44566017	C10H19NO5	233.26	CCCOCCN1C[C@H]([C@H]([C@@H](C1=O)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BJI03W	1h-Isoindole-1,3(2h)-dione, 4-nitro-2-phenyl-	Investigative	272783	C14H8N2O4	268.22	C1=CC=C(C=C1)N2C(=O)C3=C(C2=O)C(=CC=C3)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BJU2P9	(1S,2S,3S,6R)-6-(Octylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127037636	C14H28ClNO3	293.83	CCCCCCCCN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BJZU75	(3As,5R,6S,7S,7aR)-5-(hydroxymethyl)-2-(16-iodohexadecylsulfanyl)-5,6,7,7a-tetrahydro-3aH-pyrano[2,3-d][1,3]oxazole-6,7-diol	Investigative	118725789	C23H42INO5S	571.6	C(CCCCCCCCI)CCCCCCCSC1=N[C@@H]2[C@H](O1)[C@H]([C@@H]([C@H](O2)CO)O)O	IC50 = 230000 nM	Non binder
T84173	Glucosylceramidase	BK7QO5	2-Anilino-6-(hydroxymethyl)-3a,4,5,6a-tetrahydrocyclopenta[d][1,3]oxazole-4,5,6-triol	Investigative	44322630	C13H16N2O5	280.28	C1=CC=C(C=C1)NC2=NC3C(C(C(C3O2)(CO)O)O)O	IC50 > 300000 nM	Non binder
T84173	Glucosylceramidase	BKB32N	(2R,3R,4R,5S)-2-(1-Hydroxy-propyl)-piperidine-3,4,5-triol	Investigative	44338547	C8H17NO4	191.22	CCC([C@@H]1[C@H]([C@@H]([C@H](CN1)O)O)O)O	Ki = 630000 nM	Non binder
T84173	Glucosylceramidase	BKGR50	5-Methoxy-piperidine-3,4-diol	Investigative	44368232	C6H13NO3	147.17	COC1CNCC(C1O)O	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BL3Q2W	(2R,3R,4R,5S)-2-Methylpiperidine-3,4,5-triol	Investigative	10351835	C6H13NO3	147.17	C[C@@H]1[C@H]([C@@H]([C@H](CN1)O)O)O	Ki = 780000 nM	Non binder
T84173	Glucosylceramidase	BLBV83	5-Amino-1-(hydroxymethyl)cyclopentane-1,2,3,4-tetrol	Investigative	9815399	C6H13NO5	179.17	C(C1(C(C(C(C1O)O)O)N)O)O	IC50 > 300000 nM	Non binder
T84173	Glucosylceramidase	BM80CV	(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)-N-octylpyrrolidine-1-carbothioamide	Investigative	134144115	C14H28N2O3S	304.45	CCCCCCCCNC(=S)N1C[C@H]([C@@H]([C@H]1CO)O)O	IC50 = 788000 nM	Non binder
T84173	Glucosylceramidase	BNHG17	(3S,4R,5R)-3,4,5-Trihydroxy-1-(6-hydroxyhexyl)piperidin-2-one	Investigative	44138545	C11H21NO5	247.29	C1[C@H]([C@H]([C@@H](C(=O)N1CCCCCCO)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BNU27B	alpha-1-C-(1,10,13-Trihydroxytridecyl)-1,4-dideoxy-1,4-imino-D-arabinitol	Investigative	11773821	C18H37NO8	395.5	C(CCC(CO)O)CC(CC(CCC[C@H]([C@@H]1[C@H]([C@@H]([C@H](N1)CO)O)O)O)O)O	IC50 = 970000 nM	Non binder
T84173	Glucosylceramidase	BO50MW	(1S,2S,3S,6R)-6-(Decylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034618	C16H32ClNO3	321.9	CCCCCCCCCCN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BP0NK4	(3S,4R,5R)-1-Benzyl-3,4,5-trihydroxypiperidin-2-one	Investigative	44566014	C12H15NO4	237.25	C1[C@H]([C@H]([C@@H](C(=O)N1CC2=CC=CC=C2)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BP5CV3	4-Hydroxy-2-phenyl-isoindole-1,3-dione	Investigative	10752481	C14H9NO3	239.23	C1=CC=C(C=C1)N2C(=O)C3=C(C2=O)C(=CC=C3)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BP8U4S	(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[5-[(1S)-1-(4-phenylphenyl)ethoxy]pentyl]piperidine-3,4,5-triol	Investigative	118720302	C25H35NO5	429.5	C[C@@H](C1=CC=C(C=C1)C2=CC=CC=C2)OCCCCCN3C[C@@H]([C@H]([C@@H]([C@H]3CO)O)O)O	IC50 = 400000 nM	Non binder
T84173	Glucosylceramidase	BPUR78	(1S,2S,3S,6R)-6-(2-Ethylbutylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034624	C12H24ClNO3	265.78	CCC(CC)CN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BPY6K2	(3S,4R,5R)-1-Butyl-3,4,5-trihydroxypiperidin-2-one	Investigative	44566013	C9H17NO4	203.24	CCCCN1C[C@H]([C@H]([C@@H](C1=O)O)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BQ3MX5	4,5,6,7-Tetrachloro-2-(4-phenylbutyl)isoindoline-1,3-dione	Investigative	10319782	C18H13Cl4NO2	417.1	C1=CC=C(C=C1)CCCCN2C(=O)C3=C(C2=O)C(=C(C(=C3Cl)Cl)Cl)Cl	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BQ65WH	(1S,2S,3S,6R)-6-(Hexylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127035677	C12H24ClNO3	265.78	CCCCCCN[C@@H]1C=C[C@@H]([C@@H]([C@H]1O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BQ7S9T	6-Hydroxymethyl-5-(3-hydroxy-pyridin-2-ylsulfanyl)-2-methoxy-tetrahydro-pyran-3,4-diol	Investigative	44377797	C12H17NO6S	303.33	COC1C(C(C(C(O1)CO)SC2=C(C=CC=N2)O)O)O	Ki = 800000 nM	Non binder
T84173	Glucosylceramidase	BQN3Z4	(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)-N-octylpiperidine-1-carbothioamide	Investigative	134138587	C15H30N2O3S	318.5	CCCCCCCCNC(=S)N1CC[C@H]([C@@H]([C@H]1CO)O)O	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BR50UY	(2S,3R,4R,5S)-2-(Hydroxymethyl)-1-pentylpiperidine-3,4,5-triol	Investigative	9859470	C11H23NO4	233.3	CCCCCN1C[C@@H]([C@H]([C@@H]([C@@H]1CO)O)O)O	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BRD3O1	(1R,2S,4R,5S)-6-[[1-[(2-Butyl-1H-imidazol-5-yl)methyl]triazol-4-yl]methylamino]cyclohexane-1,2,3,4,5-pentol	Investigative	52937505	C17H28N6O5	396.4	CCCCC1=NC=C(N1)CN2C=C(N=N2)CNC3[C@@H]([C@H](C([C@H]([C@@H]3O)O)O)O)O	IC50 = 237000 nM	Non binder
T84173	Glucosylceramidase	BS29XW	4,5,6,7-Tetrachloro-2-phenethyl-isoindole-1,3-dione	Investigative	10385642	C16H9Cl4NO2	389.1	C1=CC=C(C=C1)CCN2C(=O)C3=C(C2=O)C(=C(C(=C3Cl)Cl)Cl)Cl	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BS2NY0	4-Nitro-N-phenylphthalimide	Investigative	762600	C14H8N2O4	268.22	C1=CC=C(C=C1)N2C(=O)C3=C(C2=O)C=C(C=C3)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BT18HM	5-(6-Dimethylaminomethyl-3-hydroxy-pyridin-2-ylsulfanyl)-6-hydroxymethyl-2-methoxy-tetrahydro-pyran-3,4-diol	Investigative	44377856	C15H24N2O6S	360.4	CN(C)CC1=NC(=C(C=C1)O)SC2C(OC(C(C2O)O)OC)CO	Ki = 20000000 nM	Non binder
T84173	Glucosylceramidase	BTIQ02	N-Phenethyl phthalimide	Investigative	348641	C16H13NO2	251.28	C1=CC=C(C=C1)CCN2C(=O)C3=CC=CC=C3C2=O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BTJX92	Pentyldnm	Investigative	129374	C11H23NO4	233.3	CCCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O	IC50 = 500000 nM	Non binder
T84173	Glucosylceramidase	BU0Z1L	N-[(3S,4R,5R)-1-Decyl-4,5-dihydroxy-6-oxopiperidin-3-yl]acetamide	Investigative	44566034	C17H32N2O4	328.4	CCCCCCCCCCN1C[C@@H]([C@H]([C@H](C1=O)O)O)NC(=O)C	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BUF7M2	N-Pentoxypentyl-1-deoxynojirimycin	Investigative	53323067	C16H33NO5	319.44	CCCCCOCCCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O	IC50 = 705000 nM	Non binder
T84173	Glucosylceramidase	BUK2T4	1-Cyano-1-deoxy-5-O-aza-alpha-D-glucopyranose	Investigative	12852767	C7H12N2O4	188.18	C([C@@H]1[C@H]([C@@H]([C@H]([C@H](N1)C#N)O)O)O)O	Ki = 716000 nM	Non binder
T84173	Glucosylceramidase	BV1U7T	N-Hexyl-L-ido-1-deoxynojirimycin	Investigative	53323483	C12H25NO4	247.33	CCCCCCN1C[C@@H]([C@H]([C@@H]([C@@H]1CO)O)O)O	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BV24DP	4-Morpholin-4-ylbutane-1,3-diol	Investigative	56679802	C8H17NO3	175.23	C1COCCN1CC(CCO)O	Ki = 640000 nM	Non binder
T84173	Glucosylceramidase	BW9M0I	N-(Adamantan-1-yl)-5-[(2S,3R,4R,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]pentanamide	Investigative	16100287	C21H36N2O5	396.5	C1C2CC3CC1CC(C2)(C3)NC(=O)CCCCN4[C@@H]([C@H]([C@@H]([C@@H]4CO)O)O)CO	IC50 = 393000 nM	Non binder
T84173	Glucosylceramidase	BWA3K0	3-Anilino-5,7a-bis(hydroxymethyl)-2,4a,6,7-tetrahydrocyclopenta[b][1,4]oxazine-5,6,7-triol	Investigative	44322883	C15H20N2O6	324.33	C1C(=NC2C(C(C(C2(O1)CO)O)O)(CO)O)NC3=CC=CC=C3	IC50 = 211000 nM	Non binder
T84173	Glucosylceramidase	BWJC90	1-Butyl-piperidine-3,4,5-triol	Investigative	44368239	C9H19NO3	189.25	CCCCN1CC(C(C(C1)O)O)O	IC50 = 530000 nM	Non binder
T84173	Glucosylceramidase	BWN0B9	(3R,4R)-1-Decyl-3,4-dihydroxypyrrolidin-2-one	Investigative	44566035	C14H27NO3	257.37	CCCCCCCCCCN1C[C@H]([C@H](C1=O)O)O	IC50 = 285000 nM	Non binder
T84173	Glucosylceramidase	BWT1L8	(3R,4R,5R)-5-(Hydroxymethyl)-1-pentylpiperidine-3,4-diol	Investigative	67508445	C11H23NO3	217.31	CCCCCN1C[C@@H]([C@H]([C@@H](C1)O)O)CO	Ki = 406060 nM	Non binder
T84173	Glucosylceramidase	BWUL98	N-[(3S,4R,5R)-4,5-Dihydroxy-1-(6-hydroxyhexyl)-6-oxopiperidin-3-yl]acetamide	Investigative	44566037	C13H24N2O5	288.34	CC(=O)N[C@H]1CN(C(=O)[C@@H]([C@@H]1O)O)CCCCCCO	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BX9Q1U	(3R,4R)-3,4-Dihydroxy-1-(6-hydroxyhexyl)pyrrolidin-2-one	Investigative	44566055	C10H19NO4	217.26	C1[C@H]([C@H](C(=O)N1CCCCCCO)O)O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BXOB21	(1S,2S,3S,6R)-6-(2-Phenylethylamino)cyclohex-4-ene-1,2,3-triol;hydrochloride	Investigative	127034632	C14H20ClNO3	285.76	C1=CC=C(C=C1)CCN[C@@H]2C=C[C@@H]([C@@H]([C@H]2O)O)O.Cl	IC50 > 1000000 nM	Non binder
T84173	Glucosylceramidase	BY3P1C	N-Benzylphthalimide	Investigative	75059	C15H11NO2	237.25	C1=CC=C(C=C1)CN2C(=O)C3=CC=CC=C3C2=O	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	BY87AN	5-Amino-2-phenylisoindole-1,3-dione	Investigative	787204	C14H10N2O2	238.24	C1=CC=C(C=C1)N2C(=O)C3=C(C2=O)C=C(C=C3)N	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	D01HDD	2-benzyl-4,5,6,7-tetrachloroisoindoline-1,3-dione	Investigative	983732	C15H7Cl4NO2	375	C1=CC=C(C=C1)CN2C(=O)C3=C(C2=O)C(=C(C(=C3Cl)Cl)Cl)Cl	IC50 > 500000 nM	Non binder
T84173	Glucosylceramidase	D0X6LK	5-hydroxy-2-phenylisoindoline-1,3-dione	Investigative	10823890	C14H9NO3	239.23	C1=CC=C(C=C1)N2C(=O)C3=C(C2=O)C=C(C=C3)O	IC50 > 500000 nM	Non binder